PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19151033-7 2009 RESULTS: Treatment with simvastatin or atorvastatin decreased CRP-induced release of CCL2, CCL3 and CCL4. Simvastatin 24-35 C-C motif chemokine ligand 3 Homo sapiens 91-95 17184493-9 2006 Macrophage inflammatory protein-1alpha protein in THP-1 monocytes was reduced from 377 to 299 and 305 pg/mL by 0.1 micro mol/L simvastatin and 0.01 micro mol/L cerivastatin, respectively. Simvastatin 127-138 C-C motif chemokine ligand 3 Homo sapiens 0-38 16321392-7 2006 Messenger RNA analysis revealed that expression of the chemokines MCP-1, MIP-1alpha and MIP-1beta, as well as the chemokine receptors CCR1, CCR2, CCR4 and CCR5, was decreased by simvastatin, both in ECs and macrophages. Simvastatin 178-189 C-C motif chemokine ligand 3 Homo sapiens 73-83 32418888-5 2020 We discovered that PCCs secrete CCL3 and stimulate IL-6, CCL2, ICAM-1 and VCAM-1 expression in MSCs and that the MSC-PCC crosstalk can be disrupted by the lipid-lowering drug simvastatin, which displays pleiotropic effects on cell metabolism and suppresses IL-6 and CCL2 production by MSCs and CCL3 secretion by PCCs. Simvastatin 175-186 C-C motif chemokine ligand 3 Homo sapiens 32-36 32418888-5 2020 We discovered that PCCs secrete CCL3 and stimulate IL-6, CCL2, ICAM-1 and VCAM-1 expression in MSCs and that the MSC-PCC crosstalk can be disrupted by the lipid-lowering drug simvastatin, which displays pleiotropic effects on cell metabolism and suppresses IL-6 and CCL2 production by MSCs and CCL3 secretion by PCCs. Simvastatin 175-186 C-C motif chemokine ligand 3 Homo sapiens 294-298