PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32016638-10	2020	Simvastatin reversed the NMDAR2B increase, restored Nur77 downward, and reduced the expression of COX-2 and TNF-alpha in MPTP-treated mice.	Simvastatin	0-11	nuclear receptor subfamily 4, group A, member 1	Mus musculus	52-57	
32016638-11	2020	This role of simvastatin was consistent with MK801 in increasing the expression of Nur77 and inhibiting NMDAR2B and cytokines in MPTP-lesioned PD mice.	Simvastatin	13-24	nuclear receptor subfamily 4, group A, member 1	Mus musculus	83-88	
32016638-12	2020	These findings suggest that reversed the NMDAR2B increase, restored Nur77 downward, and reduced the expression of COX-2 and TNF-alpha in MPTP-treated mice may be one of the mechanisms that simvastatin improves cognitive functions, depression, and anxiety in MPTP-lesioned mice.	Simvastatin	189-200	nuclear receptor subfamily 4, group A, member 1	Mus musculus	68-73	
24851101-0	2014	The Nuclear Orphan Receptor NR4A1 is Involved in the Apoptotic Pathway Induced by LPS and Simvastatin in RAW 264.7 Macrophages.	Simvastatin	90-101	nuclear receptor subfamily 4, group A, member 1	Mus musculus	28-33	
24851101-3	2014	Here, we show that the nuclear orphan receptor NR4A1 is involved in a caspase-independent apoptotic process induced by LPS and simvastatin.	Simvastatin	127-138	nuclear receptor subfamily 4, group A, member 1	Mus musculus	47-52	
24851101-4	2014	Simvastatin-induced NR4A1 expression in RAW 264.7 macrophages and ectopic expression of a dominant-negative mutant form of NR4A1 effectively suppressed both DNA fragmentation and the disruption of mitochondrial membrane potential (MMP) during LPS- and simvastatin-induced apoptosis.	Simvastatin	0-11	nuclear receptor subfamily 4, group A, member 1	Mus musculus	20-25	
24851101-4	2014	Simvastatin-induced NR4A1 expression in RAW 264.7 macrophages and ectopic expression of a dominant-negative mutant form of NR4A1 effectively suppressed both DNA fragmentation and the disruption of mitochondrial membrane potential (MMP) during LPS- and simvastatin-induced apoptosis.	Simvastatin	0-11	nuclear receptor subfamily 4, group A, member 1	Mus musculus	123-128	
24851101-4	2014	Simvastatin-induced NR4A1 expression in RAW 264.7 macrophages and ectopic expression of a dominant-negative mutant form of NR4A1 effectively suppressed both DNA fragmentation and the disruption of mitochondrial membrane potential (MMP) during LPS- and simvastatin-induced apoptosis.	Simvastatin	252-263	nuclear receptor subfamily 4, group A, member 1	Mus musculus	123-128	
24851101-6	2014	Our findings suggest that NR4A1 expression and mitochondrial translocation of Bax are related to simvastatin-induced apoptosis in LPS-activated RAW 264.7 macrophages.	Simvastatin	97-108	nuclear receptor subfamily 4, group A, member 1	Mus musculus	26-31