PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27123120-5	2016	It was demonstrated that simvastatin inhibited the EMT as assessed by reduced expression of N-cadherin and vimentin, and increased E-cadherin in TGF-beta1 treated DU145 PCa cells.	Simvastatin	25-36	vimentin	Homo sapiens	107-115	
33939900-7	2021	In the presence of simvastatin migratory abilities and vimentin expression is diminished while E-cadherin expression is increased.	Simvastatin	19-30	vimentin	Homo sapiens	55-63	
35601076-7	2022	The protein expression levels of E-cadherin were increased but those of N-cadherin, Vimentin and alpha-SMA decreased after HG and simvastatin treatment, and this was reversed by U46619.	Simvastatin	130-141	vimentin	Homo sapiens	84-92	
29401610-0	2018	An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells.	Simvastatin	99-110	vimentin	Homo sapiens	48-56	
29401610-5	2018	Simvastatin induced vimentin reorganization within 15-30 min and significant perinuclear bundling within 60 min (IC50 = 6.7 nM).	Simvastatin	0-11	vimentin	Homo sapiens	20-28	
29401610-9	2018	In SW13-vim+ cells, simvastatin, but not pravastatin, reduced total cell numbers (IC50 = 48.1 nM) and promoted apoptosis after 24 h. In contrast, SW13-vim- cell viability was unaffected by simvastatin, unless vimentin was ectopically expressed.	Simvastatin	20-31	vimentin	Homo sapiens	209-217	
29401610-10	2018	Simvastatin similarly targeted vimentin filaments and induced cell death in MDA-MB-231 (vim+), but lacked effect in MCF7 (vim-) breast cancer cells.	Simvastatin	0-11	vimentin	Homo sapiens	31-39	
29401610-11	2018	In conclusion, this study identified vimentin as a direct molecular target that mediates simvastatin-induced cell death in 2 different cancer cell lines.-Trogden, K. P., Battaglia, R. A., Kabiraj, P., Madden, V. J., Herrmann, H., Snider, N. T. An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells.	Simvastatin	89-100	vimentin	Homo sapiens	37-45	
29401610-11	2018	In conclusion, this study identified vimentin as a direct molecular target that mediates simvastatin-induced cell death in 2 different cancer cell lines.-Trogden, K. P., Battaglia, R. A., Kabiraj, P., Madden, V. J., Herrmann, H., Snider, N. T. An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells.	Simvastatin	89-100	vimentin	Homo sapiens	292-300	
29401610-11	2018	In conclusion, this study identified vimentin as a direct molecular target that mediates simvastatin-induced cell death in 2 different cancer cell lines.-Trogden, K. P., Battaglia, R. A., Kabiraj, P., Madden, V. J., Herrmann, H., Snider, N. T. An image-based small-molecule screen identifies vimentin as a pharmacologically relevant target of simvastatin in cancer cells.	Simvastatin	343-354	vimentin	Homo sapiens	37-45