PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19109527-7	2009	In addition, the intracellular cleavage of Notch (NICD) was markedly enhanced by simvastatin in BMSCs.	Simvastatin	81-92	notch receptor 1	Rattus norvegicus	43-48	
25445996-6	2015	Western blot was applied to detect the expression level of Notch-1 protein in TBI rats with simvastatin.	Simvastatin	92-103	notch receptor 1	Rattus norvegicus	59-66	
25445996-8	2015	In in vitro experiment, simvastatin induced enhanced proliferation and neurogenesis of cultured NSCs and elevated Notch-1 protein expression.	Simvastatin	24-35	notch receptor 1	Rattus norvegicus	114-121	
25445996-9	2015	Co-incubation of gamma-secretase inhibitor, an inhibitor of Notch-1 pathway, with simvastatin abolished its neurorestoration effect.	Simvastatin	82-93	notch receptor 1	Rattus norvegicus	60-67	
25445996-11	2015	CONCLUSION: Simvastatin treatment enhanced neurological functional recovery after TBI possibly via activation of Notch signaling and increasing neurogenesis in the injured area.	Simvastatin	12-23	notch receptor 1	Rattus norvegicus	113-118	
19109527-0	2009	Simvastatin enhances bone marrow stromal cell differentiation into endothelial cells via notch signaling pathway.	Simvastatin	0-11	notch receptor 1	Rattus norvegicus	89-94	
19109527-3	2009	The Notch signaling pathway, which plays a key role in multiple cell functions such as differentiation, proliferation, and apoptosis, can be regulated by simvastatin.	Simvastatin	154-165	notch receptor 1	Rattus norvegicus	4-9	
19109527-9	2009	These data suggest that simvastatin induces rat BMSCs differentiation into endothelial cells via a Notch signaling pathway.	Simvastatin	24-35	notch receptor 1	Rattus norvegicus	99-104	
18927449-6	2009	RESULTS: Simvastatin significantly increased arterial diameter, density, and vascular smooth muscle cell proliferation, and upregulated PS1, Notch1, and NICD expression in the ischemic border tissue and in the cerebral arteries compared with MCAo control rats, respectively.	Simvastatin	9-20	notch receptor 1	Rattus norvegicus	141-147	
18927449-0	2009	Simvastatin increases notch signaling activity and promotes arteriogenesis after stroke.	Simvastatin	0-11	notch receptor 1	Rattus norvegicus	22-27	
18927449-3	2009	We tested the hypothesis that simvastatin enhances arteriogenesis after stroke by increasing PS1 activation of the Notch signaling pathway.	Simvastatin	30-41	notch receptor 1	Rattus norvegicus	115-120	
18927449-12	2009	simvastatin treatment significantly increased arterial cell migration compared to control MCAo artery, whereas inhibition of Notch signaling activity by the gamma40-secretase inhibitor II significantly attenuated simvastatin-induced arterial cell migration.	Simvastatin	213-224	notch receptor 1	Rattus norvegicus	125-130