PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16020749-5	2005	Simvastatin increased ratios of stearic to palmitic, gamma-linolenic to linoleic, and arachidonic to dihomo-gamma-linolenic acid by 7.6%, 17.0%, and 10.0% (P<0.001 for all), respectively, suggesting increased fatty acid elongase and Delta6- and Delta5-desaturase enzyme activities.	Simvastatin	0-11	fatty acid desaturase 2	Homo sapiens	254-265	
22748975-0	2012	Insertion-deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin.	Simvastatin	145-156	fatty acid desaturase 2	Homo sapiens	25-30	
22748975-8	2012	Simvastatin and the LXR agonist GW3965 both upregulated expression of FADS1 and FADS2; no response was found for PPARgamma agonist rosiglitazone.	Simvastatin	0-11	fatty acid desaturase 2	Homo sapiens	80-85	
22748975-9	2012	The minor haplotype homozygotes had 20-40% higher induction of FADS1 and FADS2 after simvastatin or GW3965 treatment.	Simvastatin	85-96	fatty acid desaturase 2	Homo sapiens	73-78