PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22358108-3 2011 The effect of simvastatin on P-glycoprotein (P-gp) and cytochrome P450 (CYP) 3A4 activity was evaluated. Simvastatin 14-25 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 29-43 10464145-12 1999 mdr1b mRNA levels were moderately increased in both simvastatin-fed groups. Simvastatin 52-63 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 0-5 22358108-3 2011 The effect of simvastatin on P-glycoprotein (P-gp) and cytochrome P450 (CYP) 3A4 activity was evaluated. Simvastatin 14-25 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 45-49 20166433-10 2009 These results implied that simvastatin significantly enhanced the oral bioavailability of verapamil by inhibiting the CYP3A-mediated metabolism in small intestine or in the liver and P-glycoprotein (P-gp) efflux pump in small intestine. Simvastatin 27-38 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 183-197 20166433-10 2009 These results implied that simvastatin significantly enhanced the oral bioavailability of verapamil by inhibiting the CYP3A-mediated metabolism in small intestine or in the liver and P-glycoprotein (P-gp) efflux pump in small intestine. Simvastatin 27-38 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 199-203