PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31971101-8	2021	Considering that the statins-induced modulation of OPG is central to the statins-driven osteoprotective signalling, statins could be suggested as illustration of the role of OPG in the bone/vessels crosstalk, if further studies consolidate the contribution of OPG to the cardioprotective role of statins.	Simvastatin	21-28	TNF receptor superfamily member 11b	Homo sapiens	51-54	
17804683-0	2007	Simvastatin reduces plasma osteoprotegerin in type 2 diabetic patients with microalbuminuria.	Simvastatin	0-11	TNF receptor superfamily member 11b	Homo sapiens	27-42	
31971101-8	2021	Considering that the statins-induced modulation of OPG is central to the statins-driven osteoprotective signalling, statins could be suggested as illustration of the role of OPG in the bone/vessels crosstalk, if further studies consolidate the contribution of OPG to the cardioprotective role of statins.	Simvastatin	21-28	TNF receptor superfamily member 11b	Homo sapiens	174-177	
31971101-8	2021	Considering that the statins-induced modulation of OPG is central to the statins-driven osteoprotective signalling, statins could be suggested as illustration of the role of OPG in the bone/vessels crosstalk, if further studies consolidate the contribution of OPG to the cardioprotective role of statins.	Simvastatin	21-28	TNF receptor superfamily member 11b	Homo sapiens	174-177	
31971101-8	2021	Considering that the statins-induced modulation of OPG is central to the statins-driven osteoprotective signalling, statins could be suggested as illustration of the role of OPG in the bone/vessels crosstalk, if further studies consolidate the contribution of OPG to the cardioprotective role of statins.	Simvastatin	73-80	TNF receptor superfamily member 11b	Homo sapiens	51-54	
31971101-8	2021	Considering that the statins-induced modulation of OPG is central to the statins-driven osteoprotective signalling, statins could be suggested as illustration of the role of OPG in the bone/vessels crosstalk, if further studies consolidate the contribution of OPG to the cardioprotective role of statins.	Simvastatin	73-80	TNF receptor superfamily member 11b	Homo sapiens	51-54	
31971101-8	2021	Considering that the statins-induced modulation of OPG is central to the statins-driven osteoprotective signalling, statins could be suggested as illustration of the role of OPG in the bone/vessels crosstalk, if further studies consolidate the contribution of OPG to the cardioprotective role of statins.	Simvastatin	73-80	TNF receptor superfamily member 11b	Homo sapiens	51-54	
22399266-11	2012	Finally, the expression of OPG in AOBs and PDLs was stimulated by 1-10 and 100 nM simvastatin, respectively.	Simvastatin	82-93	TNF receptor superfamily member 11b	Homo sapiens	27-30	
21431270-4	2010	RESULTS: 10-9mol/L and 10-8mol/L concentrations of simvastatin slightly promoted MG63 cell proliferation; 10-7mol/L and 10-6mol/L concentrations of simvastatin greatly enhanced the OPG and OC mRNA expression; All concentrations of simvastatin had an inhibitory effect on MG63 cell migration.	Simvastatin	51-62	TNF receptor superfamily member 11b	Homo sapiens	181-184	
21431270-4	2010	RESULTS: 10-9mol/L and 10-8mol/L concentrations of simvastatin slightly promoted MG63 cell proliferation; 10-7mol/L and 10-6mol/L concentrations of simvastatin greatly enhanced the OPG and OC mRNA expression; All concentrations of simvastatin had an inhibitory effect on MG63 cell migration.	Simvastatin	148-159	TNF receptor superfamily member 11b	Homo sapiens	181-184	
21431270-4	2010	RESULTS: 10-9mol/L and 10-8mol/L concentrations of simvastatin slightly promoted MG63 cell proliferation; 10-7mol/L and 10-6mol/L concentrations of simvastatin greatly enhanced the OPG and OC mRNA expression; All concentrations of simvastatin had an inhibitory effect on MG63 cell migration.	Simvastatin	148-159	TNF receptor superfamily member 11b	Homo sapiens	181-184	
24555750-5	2014	Serum OPG concentrations were significantly higher in the simvastatin-treated patients with hyperlipidemia than in the diet-treated patients with hyperlipidemia (P = 0.05).	Simvastatin	58-69	TNF receptor superfamily member 11b	Homo sapiens	6-9	
24555750-7	2014	CONCLUSIONS: Within the limits of this study, the findings suggest that the intake of simvastatin is associated with increasing serum OPG concentrations, and this could have a protective effect against bone breakdown and periodontal attachment loss.	Simvastatin	86-97	TNF receptor superfamily member 11b	Homo sapiens	134-137	
24307429-7	2014	Apart from significantly reducing plasma total cholesterol and LDL, simvastatin also reduced serum levels of fetuin-A (by ~62.6 %), OPG (by ~47.2 %), OPN (by ~44.6 %) and hsCRP (by ~45.3 %) (p < 0.05) in SG patients.	Simvastatin	68-79	TNF receptor superfamily member 11b	Homo sapiens	132-135	
24307429-10	2014	Simvastatin treatment for 6 months significantly decreased serum fetuin-A, OPG and OPN levels, but the clinical relevance of this requires further investigation.	Simvastatin	0-11	TNF receptor superfamily member 11b	Homo sapiens	75-78