PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22805089-7 2012 After the treatment, GXK decoction and simvastatin decreased the expressions of PPARgamma, LXRalpha and ABCA1 (P<0.05). Simvastatin 39-50 ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus 104-109 25749868-5 2015 In J774A.1 mouse macrophage, labelled with 3H-cholesterol, ABCA1 mRNA and ABCA1-mediated cholesterol efflux were decreased by 1 muM statin: simvastatin > pitavastatin > atorvastatin > rosuvastatin > pravastatin. Simvastatin 140-151 ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus 59-64 25749868-5 2015 In J774A.1 mouse macrophage, labelled with 3H-cholesterol, ABCA1 mRNA and ABCA1-mediated cholesterol efflux were decreased by 1 muM statin: simvastatin > pitavastatin > atorvastatin > rosuvastatin > pravastatin. Simvastatin 140-151 ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus 74-79 21762915-3 2011 Phagocytosis was found to be enhanced by pravastatin, rosuvastatin and simvastatin and cyclodextrin in J774 macrophages, as cellular cholesterol was reduced and expressions of the cholesterol-related genes were modulated, including an increase of ABCA7 mRNA and decrease of ABCA1 mRNA. Simvastatin 71-82 ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus 274-279 21241519-7 2011 Real-time PCR detection disclosed that the expression of several transporters involved in reverse cholesterol transport, including macrophage scavenger receptor class B type I, hepatic ATP-binding cassette (ABC) transporters ABCG5, and ABCB4 were induced by simvastatin treatment, the expression of hepatic ABCA1 and apoA-I, which play roles in the maturation of HDL-C, were also elevated in simvastatin treated groups. Simvastatin 258-269 ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus 307-312 21241519-9 2011 We confirmed here for the first time simvastatin increased the expression of hepatic ABCB4 and ABCG5, which involved in secretion of cholesterol and bile acids into the bile, besides upregulated ABCA1 and apoA-I. Simvastatin 37-48 ATP-binding cassette, sub-family A (ABC1), member 1 Mus musculus 195-200