PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30312114-5	2019	In human myometrial cells, simvastatin reduced proinflammatory mediator mRNA and protein expression (IL-6 and IL-8) and increased anti-inflammatory cytokine mRNA expression (IL-10 and IL-13).	Simvastatin	27-38	interleukin 13	Homo sapiens	184-189	
16682645-6	2006	The Th2-biased transcription factor profile induced by simvastatin-treated DCs also was accompanied by increased Th2 (IL-4, IL-5, and IL-13) and decreased Th1 (IFN-gamma) cytokine secretion from the T cells.	Simvastatin	55-66	interleukin 13	Homo sapiens	134-139	
27343379-8	2016	beta-hydroxy-simvastatin acid (activated simvastatin) suppressed IL-5 and IL-13 in pure Th2- and Tc2-cells.	Simvastatin	13-24	interleukin 13	Homo sapiens	74-79	
27343379-9	2016	Simvastatin suppressed IL-5 and IL-13 in Th2-cells co-cultivated with monocytes or AM, which was partially reversed by the carboxylesterase inhibitor benzil.	Simvastatin	0-11	interleukin 13	Homo sapiens	32-37	
27343379-12	2016	Simvastatin requires activation in accessory cells likely by carboxylesterase to suppress IL-5 and IL-13 in Th2/Tc2-cells.	Simvastatin	0-11	interleukin 13	Homo sapiens	99-104	
27557561-0	2016	Simvastatin up-regulates adenosine deaminase and suppresses osteopontin expression in COPD patients through an IL-13-dependent mechanism.	Simvastatin	0-11	interleukin 13	Homo sapiens	111-116	
27557561-5	2016	RESULTS: Simvastatin decreased sputum IL-13, OPN and CD73, while increasing ADA expression, irrespective of inhaled corticosteroid treatment and smoking status in parallel to increased inosine levels.	Simvastatin	9-20	interleukin 13	Homo sapiens	38-43	
27557561-8	2016	Simvastatin treatment inhibited IL-13 transcription in a dose-dependent manner, and therefore diminished the IL-13-induced increase in OPN and restored IL-13-suppressed ADA.	Simvastatin	0-11	interleukin 13	Homo sapiens	32-37	
27557561-8	2016	Simvastatin treatment inhibited IL-13 transcription in a dose-dependent manner, and therefore diminished the IL-13-induced increase in OPN and restored IL-13-suppressed ADA.	Simvastatin	0-11	interleukin 13	Homo sapiens	109-114	
27557561-8	2016	Simvastatin treatment inhibited IL-13 transcription in a dose-dependent manner, and therefore diminished the IL-13-induced increase in OPN and restored IL-13-suppressed ADA.	Simvastatin	0-11	interleukin 13	Homo sapiens	109-114	
27557561-10	2016	CONCLUSION: Simvastatin reversed IL-13-suppressed ADA activity that leads to the down-regulation of adenosine signaling and therefore inhibits OPN expression through the direct inhibition of IL-13-activated STAT6 pathway.	Simvastatin	12-23	interleukin 13	Homo sapiens	33-38	
27557561-10	2016	CONCLUSION: Simvastatin reversed IL-13-suppressed ADA activity that leads to the down-regulation of adenosine signaling and therefore inhibits OPN expression through the direct inhibition of IL-13-activated STAT6 pathway.	Simvastatin	12-23	interleukin 13	Homo sapiens	191-196