PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19595129-8 2009 RESULTS: The mPAP of the simvastatin intervention group was (23 +/- 7) mm Hg, significantly lower than that of the PH group [(34 +/- 9) mm Hg, P < 0.05], but not significantly different from that of the normal control group [(20 +/- 4) mm Hg, P > 0.05]. Simvastatin 25-36 phospholipid phosphatase 1 Mus musculus 13-17 22971207-5 2012 RESULTS: The combination of tadalafil and simvastatin showed significantly more improvement in the mean pulmonary hypertension pressure (mPAP) and right ventricular hypertrophy compared with each monotherapy (p < 0.05). Simvastatin 42-53 phospholipid phosphatase 1 Mus musculus 137-141 12963647-5 2003 When rats with severe PAH received simvastatin (2 mg x kg(-1) x d(-1) by gavage) from week 11, there was 100% survival and reversal of PAH after 2 weeks (mPAP=36 mm Hg) and 6 weeks (mPAP=24 mm Hg) of therapy. Simvastatin 35-46 phospholipid phosphatase 1 Mus musculus 154-158 12963647-5 2003 When rats with severe PAH received simvastatin (2 mg x kg(-1) x d(-1) by gavage) from week 11, there was 100% survival and reversal of PAH after 2 weeks (mPAP=36 mm Hg) and 6 weeks (mPAP=24 mm Hg) of therapy. Simvastatin 35-46 phospholipid phosphatase 1 Mus musculus 182-186 25674219-7 2014 Treatment with simvastatin resulted in a significant decrease not only in mPAP and RVHI but also in a 5-HTT level in serum and BALF (P < 0.01 or 0.05) with a good correlation between the 5-HTT level and mPAP or RVHI (r = 0.693 and 0.479; 0.675 and 0.508). Simvastatin 15-26 phospholipid phosphatase 1 Mus musculus 74-78 25674219-7 2014 Treatment with simvastatin resulted in a significant decrease not only in mPAP and RVHI but also in a 5-HTT level in serum and BALF (P < 0.01 or 0.05) with a good correlation between the 5-HTT level and mPAP or RVHI (r = 0.693 and 0.479; 0.675 and 0.508). Simvastatin 15-26 phospholipid phosphatase 1 Mus musculus 206-210 24124673-10 2013 CONCLUSIONS: The combined use of beraprost and simvastatin may delay the increase of mPAP and remodeling of pulmonary vessels and inhibit right ventricular hypertrophy in pulmonary arterial hypertension rats. Simvastatin 47-58 phospholipid phosphatase 1 Mus musculus 85-89