PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17038636-0 2006 Suppression of RAGE as a basis of simvastatin-dependent plaque stabilization in type 2 diabetes. Simvastatin 34-45 long intergenic non-protein coding RNA 914 Homo sapiens 15-19 17038636-4 2006 Thus, the aim of this study was to characterize the effect of simvastatin on the expression of RAGE and RAGE-dependent plaque-destabilizing genes in human atherosclerotic plaques. Simvastatin 62-73 long intergenic non-protein coding RNA 914 Homo sapiens 95-99 17038636-4 2006 Thus, the aim of this study was to characterize the effect of simvastatin on the expression of RAGE and RAGE-dependent plaque-destabilizing genes in human atherosclerotic plaques. Simvastatin 62-73 long intergenic non-protein coding RNA 914 Homo sapiens 104-108 17038636-8 2006 Of interest, RAGE inhibition by simvastatin, observed not only in plaque sections but also in plaque-derived macrophages, was reverted by addition of AGEs in vitro. Simvastatin 32-43 long intergenic non-protein coding RNA 914 Homo sapiens 13-17 17038636-9 2006 CONCLUSIONS: This study supports the hypothesis that simvastatin inhibits plaque RAGE expression by decreasing MPO-dependent AGE generation. Simvastatin 53-64 long intergenic non-protein coding RNA 914 Homo sapiens 81-85