PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29361314-0	2018	Simvastatin alters M1/M2 polarization of murine BV2 microglia via Notch signaling.	Simvastatin	0-11	notch 1	Mus musculus	66-71	
32393497-0	2020	Simvastatin improves cardiac function through Notch1 activation in BALB/c mice with chronic Chagas cardiomyopathy.	Simvastatin	0-11	notch 1	Mus musculus	46-52	
32393497-5	2020	Furthermore, several reports suggest that simvastatin activates the Notch pathway after stroke in cerebral endothelial cells, enhancing blood flow by promoting angiogenesis.	Simvastatin	42-53	notch 1	Mus musculus	68-73	
32393497-8	2020	At 80 days postinfection, the heart tissues were assessed for Notch1 activity.Key Results: T. cruzi infection activated the Notch1 pathway, and simvastatin (but not 15-epi-lipoxin A4) produced a further increase in that activity, correlating with improvement in the ejection fraction and histopathologic findings typical of T. cruzi infection, including improvements in inflammation and fibrosis.	Simvastatin	144-155	notch 1	Mus musculus	62-68	
32393497-9	2020	Moreover, simvastatin increased isolectin B4+ cells suggesting active angiogenesis in the chronically infected hearts without altering the parasitic load.Conclusions and Implications: Simvastatin, probably acting through the Notch1 pathway, decreases inflammation, improving cardiac function in chronically T. cruzi-infected mice.	Simvastatin	10-21	notch 1	Mus musculus	225-231	
32393497-9	2020	Moreover, simvastatin increased isolectin B4+ cells suggesting active angiogenesis in the chronically infected hearts without altering the parasitic load.Conclusions and Implications: Simvastatin, probably acting through the Notch1 pathway, decreases inflammation, improving cardiac function in chronically T. cruzi-infected mice.	Simvastatin	184-195	notch 1	Mus musculus	225-231	
29361314-4	2018	Moreover, simvastatin enhance the expression of Notch signaling molecules, and its regulatory effects were blocked in Notch1 knocked down cells.	Simvastatin	10-21	notch 1	Mus musculus	48-53	
29361314-4	2018	Moreover, simvastatin enhance the expression of Notch signaling molecules, and its regulatory effects were blocked in Notch1 knocked down cells.	Simvastatin	10-21	notch 1	Mus musculus	118-124	
29361314-5	2018	In conclusion, these findings indicated that simvastatin alters M1/M2 polarization of murine BV2 microglia via Notch signaling.	Simvastatin	45-56	notch 1	Mus musculus	111-116