PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12036910-6 2002 Although the S-nitrosylcysteine adduct in hAGT is readily reversible by reaction with other cellular thiols, the formation of S-nitrosocysteine at Cys-145 was found to lead to the rapid degradation of the hAGT protein in vivo. Sulfhydryl Compounds 101-107 angiotensinogen Homo sapiens 42-46 1531616-0 1992 Neocarzinostatin-mediated DNA damage in a model AGT.ACT site: mechanistic studies of thiol-sensitive partitioning of C4" DNA damage products. Sulfhydryl Compounds 85-90 angiotensinogen Homo sapiens 48-51 9030406-4 1997 A Glu-thiol inhibitor of aminopeptidase A also reduced angiotensin II-induced drinking. Sulfhydryl Compounds 6-11 angiotensinogen Homo sapiens 55-69 1531616-7 1992 Production of 3"-phosphoglycolate residues, restricted mainly to the T of AGT in bistranded lesions, correlated with the incidence of direct DS breaks in the AGT.ACT model and in plasmid DNA and appeared to be influenced by the reducing power of the thiol activator. Sulfhydryl Compounds 250-255 angiotensinogen Homo sapiens 158-161 1531616-3 1992 Structure-function studies revealed that a variety of different thiols produced bistranded lesions in this model by predominantly C4"-hydrogen atom abstraction (84-93%) at the T of AGT and C5"-hydrogen atom abstraction (87-91%) at the T of ACT. Sulfhydryl Compounds 64-70 angiotensinogen Homo sapiens 181-184 17941088-8 2008 The thiol antioxidant, N-acetyl cysteine (NAC), completely inhibited stretch- and Ang II-induced apoptosis. Sulfhydryl Compounds 4-9 angiotensinogen Homo sapiens 82-88 2548550-9 1989 The intention was to replace the thiol side chain with a homophenylalanine unit to bind to the zinc ion and also to occupy the S1 site which fits the Phe8 side chain of angiotensin I. Sulfhydryl Compounds 33-38 angiotensinogen Homo sapiens 169-182 31069778-2 2019 Angiotensinogen is found in two distinct posttranslational forms in the plasma, an oxidized and a reduced (free thiol) form. Sulfhydryl Compounds 112-117 angiotensinogen Homo sapiens 0-15 31069778-4 2019 We have developed novel ELISA assays to quantitate the levels of total and free thiol angiotensinogen allowing for calculation of the amount of oxidized angiotensinogen species. Sulfhydryl Compounds 80-85 angiotensinogen Homo sapiens 86-101 26312482-1 2015 OBJECTIVE: Angiotensinogen exists in two distinct redox forms in plasma, the oxidized sulfhydryl-bridge form and the reduced, unbridged, free thiol form. Sulfhydryl Compounds 142-147 angiotensinogen Homo sapiens 11-26 26312482-2 2015 The oxidized form of angiotensinogen compared to the free thiol form preferentially interacts with renin resulting in increased generation of angiotensin. Sulfhydryl Compounds 58-63 angiotensinogen Homo sapiens 21-36 26312482-7 2015 The oxidized angiotensinogen plasma level is derived by subtracting the level of free thiol, reduced angiotensinogen from the total angiotensinogen levels in the plasma. Sulfhydryl Compounds 86-91 angiotensinogen Homo sapiens 13-28 26312482-10 2015 CONCLUSION: Patients with pre-eclampsia had substantially lower levels of free thiol angiotensinogen compared to healthy pregnant controls, whilst maintaining similar total angiotensinogen levels in the plasma. Sulfhydryl Compounds 79-84 angiotensinogen Homo sapiens 85-100 20927107-5 2010 Here we show that the reduced unbridged form of angiotensinogen is present in the circulation in a near 40:60 ratio with the oxidized sulphydryl-bridged form, which preferentially interacts with receptor-bound renin. Sulfhydryl Compounds 134-144 angiotensinogen Homo sapiens 48-63 20927107-7 2010 Specifically, we demonstrate the oxidative switch of angiotensinogen to its more active sulphydryl-bridged form in the maternal circulation in pre-eclampsia-the hypertensive crisis of pregnancy that threatens the health and survival of both mother and child. Sulfhydryl Compounds 88-98 angiotensinogen Homo sapiens 53-68