PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21332028-9 2011 ACTH increased PER1 mRNA, BMAL1, StAR, and 3beta-HSD protein levels, and cortisol and progesterone production. Progesterone 86-98 proopiomelanocortin Homo sapiens 0-4 24952092-7 2014 Contrary to our initial prediction of an inverse relationship, progesterone and allopregnanolone were positively associated with ACTH. Progesterone 63-75 proopiomelanocortin Homo sapiens 129-133 24952092-8 2014 Progesterone and allopregnanolone partially mediated the relationship between PTSD and ACTH. Progesterone 0-12 proopiomelanocortin Homo sapiens 87-91 24952092-10 2014 Progesterone and allopregnanolone partially mediated the ACTH response in PTSD. Progesterone 0-12 proopiomelanocortin Homo sapiens 57-61 15834733-8 2005 CONCLUSIONS: The results suggest that CRH and ACTH directly modulate the endocrine function of trophoblasts in culture by downregulating progesterone production. Progesterone 137-149 proopiomelanocortin Homo sapiens 46-50 17348967-9 2007 However, the ACTH group had significantly (p < 0.05) fewer ova/embryos retrieved (51%) than the C group (81%), and there was a tendency towards faster transportation to the uterus in the ACTH group, possibly because of high progesterone concentrations during treatment. Progesterone 227-239 proopiomelanocortin Homo sapiens 13-17 17348967-9 2007 However, the ACTH group had significantly (p < 0.05) fewer ova/embryos retrieved (51%) than the C group (81%), and there was a tendency towards faster transportation to the uterus in the ACTH group, possibly because of high progesterone concentrations during treatment. Progesterone 227-239 proopiomelanocortin Homo sapiens 190-194 18697912-8 2008 In adrenalectomized ewes chronically replaced to 0.35 mg x kg(-1) x day(-1) cortisol, plasma ACTH concentrations were decreased significantly in the nonpregnant progesterone-treated ewes compared with the ovariectomized nonpregnant ewes. Progesterone 161-173 proopiomelanocortin Homo sapiens 93-97 18697912-9 2008 With 0.5 mg x kg(-1) x day(-1) cortisol, plasma ACTH levels were greater in pregnant ewes than in nonpregnant ewes with or without progesterone. Progesterone 131-143 proopiomelanocortin Homo sapiens 48-52 18697912-12 2008 We conclude that increased progesterone does not alter the feedback relation of cortisol to ACTH, but may modulate ACTH indirectly through plasma volume. Progesterone 27-39 proopiomelanocortin Homo sapiens 115-119 17825902-10 2007 ACTH administration increased both cortisol (P<0.001) and progesterone concentrations (P<0.01) compared to CTR group. Progesterone 61-73 proopiomelanocortin Homo sapiens 0-4 16870362-7 2007 ACTH treatment caused a significant increase in plasma levels of cortisol, progesterone, androstenedione and testosterone in all mares (P<0.05). Progesterone 75-87 proopiomelanocortin Homo sapiens 0-4 16580171-10 2007 In conclusion, injections of synthetic ACTH during estrus in the sow apparently disturb the duration of signs of standing estrus and the hormonal pattern of progesterone, and possibly of inhibin alpha, estradiol and LH. Progesterone 157-169 proopiomelanocortin Homo sapiens 39-43 15572653-4 2005 CRH and ACTH also enhanced production of cortisol and corticosterone, and cortisol production was also stimulated by progesterone. Progesterone 117-129 proopiomelanocortin Homo sapiens 8-12 11925385-7 2002 RESULTS: During the suppression of endogenous gonadotrophin secretion progesterone levels rose after the administration of ACTH, but not of GnRH. Progesterone 70-82 proopiomelanocortin Homo sapiens 123-127 11925385-9 2002 The ACTH-stimulated concentration of progesterone and of 17alpha-hydroxyprogesterone were significantly reduced during intake of ethinyl estradiol. Progesterone 37-49 proopiomelanocortin Homo sapiens 4-8 10967241-0 2000 Effect of ACTH-challenge on progesterone and cortisol levels in ovariectomised repeat breeder heifers. Progesterone 28-40 proopiomelanocortin Homo sapiens 10-14 12018035-3 2002 In general, estradiol and testosterone exert a stimulatory, progesterone an inhibitory effect on neuronal activities which are mediated by excitatory (e.g. glutamate, aspartate), and inhibitory amino acids (e.g. GABA) and neuropeptides (e.g. beta-endorphin), respectively. Progesterone 60-72 proopiomelanocortin Homo sapiens 242-256 12018035-5 2002 The discharges of GnRH neurons triggered by excitatory amino acids are modulated by estradiol, while the inhibitory effect of progesterone is mediated by GABA and beta-endorphin which cause hyperpolarization of the GnRH neurons and consequently a reduced pulse frequency. Progesterone 126-138 proopiomelanocortin Homo sapiens 163-177 11192189-7 2000 Progesterone and PGF2alpha metabolite levels were significantly (P<0.05) elevated only after the first ACTH administration. Progesterone 0-12 proopiomelanocortin Homo sapiens 106-110 9592947-1 1998 The effect of adrenocorticotropic hormone (ACTH) administration on progesterone and cortisol concentrations was determined in lactating primiparous sows. Progesterone 67-79 proopiomelanocortin Homo sapiens 14-41 10887750-1 2000 In order to elucidate the effect of stress on reproductive hormones, the present study was designed to investigate the effect of adrenocorticotropic hormone (ACTH) on the plasma levels of cortisol, progesterone, oestradiol-17 beta and prostaglandin F2 alpha metabolite in ovariectomized gilts. Progesterone 198-210 proopiomelanocortin Homo sapiens 129-156 10887750-1 2000 In order to elucidate the effect of stress on reproductive hormones, the present study was designed to investigate the effect of adrenocorticotropic hormone (ACTH) on the plasma levels of cortisol, progesterone, oestradiol-17 beta and prostaglandin F2 alpha metabolite in ovariectomized gilts. Progesterone 198-210 proopiomelanocortin Homo sapiens 158-162 10887750-5 2000 The administration of ACTH was followed by a concomitant elevation of cortisol, progesterone and prostaglandin F2 alpha metabolite but not of oestradiol-17 beta. Progesterone 80-92 proopiomelanocortin Homo sapiens 22-26 10887750-7 2000 The total area under the curve for cortisol, progesterone and prostaglandin F2 alpha metabolite was significantly higher in the ACTH than in the control group. Progesterone 45-57 proopiomelanocortin Homo sapiens 128-132 10887750-9 2000 It can be concluded that the administration of ACTH to ovariectomized gilts, results in the elevation of cortisol, progesterone and prostaglandin F2 alpha metabolite but not of oestradiol-17 beta. Progesterone 115-127 proopiomelanocortin Homo sapiens 47-51 9592947-1 1998 The effect of adrenocorticotropic hormone (ACTH) administration on progesterone and cortisol concentrations was determined in lactating primiparous sows. Progesterone 67-79 proopiomelanocortin Homo sapiens 43-47 9174847-7 1997 The beta-endorphin level has a negative correlation with the LH level (r = -0.50, p < 0.001) on the preovulatory days, and during the luteal phase a positive linear correlation (r = 0.47, p < 0.001) is found with the progesterone level. Progesterone 223-235 proopiomelanocortin Homo sapiens 4-18 8232772-6 1993 ME in vivo release of LHRH and beta-END increase from the luteal (low LH/high progesterone, P4) to the follicular phase (high LH/low P4). Progesterone 78-90 proopiomelanocortin Homo sapiens 31-39 9002999-1 1997 Reported studies using the conventional pituitary cell culture technique suggest that beta-endorphin (B-EP) produced locally in the pituitary or reaching it from the hypothalamus acts in conjunction with estradiol (E2) to initiate and in conjunction with progesterone (P4) to terminate the midcycle surge of LH. Progesterone 255-267 proopiomelanocortin Homo sapiens 86-100 9002999-1 1997 Reported studies using the conventional pituitary cell culture technique suggest that beta-endorphin (B-EP) produced locally in the pituitary or reaching it from the hypothalamus acts in conjunction with estradiol (E2) to initiate and in conjunction with progesterone (P4) to terminate the midcycle surge of LH. Progesterone 255-267 proopiomelanocortin Homo sapiens 102-106 9363986-6 1997 ACTH and cortisol were robustly elevated and these elevations related significantly to changes in progesterone but not testosterone. Progesterone 98-110 proopiomelanocortin Homo sapiens 0-4 2848944-4 1988 In ovariectomized ewes, ACTH significantly elevated the response of both cortisol and progesterone (r = 0.75, P less than 0.001) within 10-15 min of injection. Progesterone 86-98 proopiomelanocortin Homo sapiens 24-28 1369589-16 1992 Levels of POMC mRNA in the MBH were increased (p < 0.01) by both estradiol and progesterone as compared with the no steroid group. Progesterone 82-94 proopiomelanocortin Homo sapiens 10-14 1334002-19 1992 One group of cells that store ACTH with gonadotropins may function in the proestrous female to stimulate adrenal progesterone. Progesterone 113-125 proopiomelanocortin Homo sapiens 30-34 1756018-6 1991 Oestradiol and progesterone increase beta-endorphin concentrations in the luteal phase of the menstrual cycle, and this is followed by a rapid fall at menstruation. Progesterone 15-27 proopiomelanocortin Homo sapiens 37-51 2172272-7 1990 Second, the negative correlation between time-integrated plasma ACTH and cortisol responses to oCRH and basal luteal progesterone concentrations present in normal control women was not seen in the PMS patients. Progesterone 117-129 proopiomelanocortin Homo sapiens 64-68 2848944-5 1988 In the ovariectomized ewes and during heat stress, the responses of progesterone and cortisol to ACTH were characterized by an initial acute rise, a transient drop, a steep elevation and a gradual but prolonged decline. Progesterone 68-80 proopiomelanocortin Homo sapiens 97-101 6323871-4 1984 Indeed, extremely high levels of pregnenolone, pregnenolone sulfate, progesterone were found in association with low plasma levels of delta 4-androstenedione, testosterone, dehydroepiandrosterone and its sulfate, while cortisol 17OH-progesterone and ACTH levels and plasma renin activity were normal. Progesterone 69-81 proopiomelanocortin Homo sapiens 250-254 2932351-4 1985 The highest concentrations of IR beta-EP in FF were found in the largest follicles, whereas in the PF they correlated with the luteal period of the menstrual cycle and with progesterone concentrations. Progesterone 173-185 proopiomelanocortin Homo sapiens 33-40 6098492-3 1984 The release of beta-endorphin from these hypothalamic neurons is influenced by gonadal steroids, maximal release being observed when both estradiol and progesterone are present. Progesterone 152-164 proopiomelanocortin Homo sapiens 15-29 3139743-7 1988 ACTH stimulation induced a subnormal rise of cortisol and 11 beta-hydroxyandrostenedione, a low or absent rise of dehydroepiandrosterone, 17 alpha-hydroxypregnenolone, androstenedione and 17 alpha-hydroxyprogesterone contrasting with a marked rise of pregnenolone and progesterone. Progesterone 204-216 proopiomelanocortin Homo sapiens 0-4 3017465-0 1986 Stimulation of progesterone production by adrenocorticotropic hormone and prostaglandin E2 in rat luteal cells. Progesterone 15-27 proopiomelanocortin Homo sapiens 42-69 3017465-6 1986 ACTH, PGE2 and hCG increased synthesis of progesterone, and the combination of hCG with ACTH or PGE2 further increased production of the hormone. Progesterone 42-54 proopiomelanocortin Homo sapiens 0-4 3018717-1 1986 We have studied the possible function of the placental adrenocorticotrophic hormone-(ACTH-) like substance (PALS) in placental steroidogenesis by measuring oestradiol (E2) and progesterone (P4) in term human placental explants incubated with commercially available porcine ACTH I-39. Progesterone 176-188 proopiomelanocortin Homo sapiens 85-89 6320915-0 1984 Ability of cortisol and progesterone to mediate the stimulatory effect of adrenocorticotropic hormone upon testosterone production by the porcine testis. Progesterone 24-36 proopiomelanocortin Homo sapiens 74-101 570445-5 1978 Exposure to an environmental temperature of 32 degrees C for three hours or injection of 1 IU/kg bodyweight of ACTH for each of two ovariectomized sows resulted in an elevation in progesterone values to 5-7 ng/ml plasma from basal levels of 1-2 ng/ml and a rise in total glucocorticosteroids from basal levels of 1 or 2 microgram/100 ml plasma to 4-10 microgram/100 ml. Progesterone 180-192 proopiomelanocortin Homo sapiens 111-115 6300159-1 1983 We have studied the response of blood levels of progesterone, 17-hydroxyprogesterone, 11-deoxycortisol, and cortisol to acute ACTH stimulation in children with isolated GH deficiency. Progesterone 48-60 proopiomelanocortin Homo sapiens 126-130 6119250-11 1981 This work may show that ACTH infusion induced uterine contractions by increased corticosteroids via placenta in lower ratio of progesterone to estrogen but it does not provide any precise information on the mechanism of initiation of human labor. Progesterone 127-139 proopiomelanocortin Homo sapiens 24-28 6319907-1 1983 The purpose of this study was to investigate the effect of oral administration of progesterone (15 micrograms norethindrone, NE) in presence and absence of estradiol (1 microgram ethinyl estradiol, EE2) on the CNS levels of beta-endorphin like immunoreactivity (beta-EI) in female rats. Progesterone 82-94 proopiomelanocortin Homo sapiens 224-238 7435115-7 1980 Correlation between circadian variations of progesterone and cortisol suggests, that progesterone levels are modified by ACTH secretion. Progesterone 44-56 proopiomelanocortin Homo sapiens 121-125 4324509-0 1969 [Effect of testosterone, estradiol, progesterone, and their derivatives on the release of ACTH]. Progesterone 36-48 proopiomelanocortin Homo sapiens 90-94 192874-1 1977 The response of plasma progesterone, 17 alpha-hydroxyprogesterone (17-OHP), and cortisol to intravenous ACTH was determined in 16 control subjects and seven sets of parents of children with congenital virilizing adrenal hyperplasia. Progesterone 23-35 proopiomelanocortin Homo sapiens 104-108 191557-4 1977 The increase in ACTH release induced by hypothalamic extract of vasopressin was reduced by corticossterone, cortisol or progesterone but not by testosterone or oestradiol, but the increase in pituitary ACTH content was not affected by any of these steroids. Progesterone 120-132 proopiomelanocortin Homo sapiens 16-20 190605-0 1976 [Effect of ACTH on the transformation of progesterone by the adrenal glands of human fetuses in vitro]. Progesterone 41-53 proopiomelanocortin Homo sapiens 11-15 190605-1 1976 It was shown in vitro that ACTH influenced the progesterone transformation increasing corticosterone production only in those fetuses whose adrenal glands, in the absence of ACTH, transformed progesterone chiefly into hydrocortisone (8--12-week fetuses). Progesterone 47-59 proopiomelanocortin Homo sapiens 27-31 190605-3 1976 The results obtained and also the data on ACTH content in the hypophysis and the blood of human fetuses at various periods of prenatal development indicated that the changes in progesterone transformation occurring with the advance of fetal age was caused by endogenous ACTH. Progesterone 177-189 proopiomelanocortin Homo sapiens 42-46 190605-3 1976 The results obtained and also the data on ACTH content in the hypophysis and the blood of human fetuses at various periods of prenatal development indicated that the changes in progesterone transformation occurring with the advance of fetal age was caused by endogenous ACTH. Progesterone 177-189 proopiomelanocortin Homo sapiens 270-274 176855-3 1976 ACTH stimulated corticoidogenesis, particularly cortisol secretion, and markedly enhanced the incorporation of progesterone and pregnenolone into cortisol. Progesterone 112-124 proopiomelanocortin Homo sapiens 0-4 946146-1 1976 In healthy women (21-28 years) the influence of synthetic alpha-MSH upon the peripheral plasms levels of LH, FSH, progesterone and cortisol was determined during the corpus luteum phase of the menstrual cycle. Progesterone 114-126 proopiomelanocortin Homo sapiens 58-67 4305376-6 1969 The adrenal cortex has the capacity to synthesize and secrete 17-OHP and progesterone since adrenocorticotrophic hormone (ACTH) caused a fourfold increase in these plasma steroids. Progesterone 73-85 proopiomelanocortin Homo sapiens 122-126 13067408-0 1953 [Relations of the anterior pituitary corticotropic hormone (ACTH) and progesterone]. Progesterone 70-82 proopiomelanocortin Homo sapiens 60-64