PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26989199-4	2016	We show that ABHD2 is highly expressed in spermatozoa, binds progesterone, and acts as a progesterone-dependent lipid hydrolase by depleting the endocannabinoid 2-arachidonoylglycerol (2AG) from plasma membrane.	Progesterone	61-73	abhydrolase domain containing 2, acylglycerol lipase	Homo sapiens	13-18	
26989199-6	2016	This study reveals that progesterone-activated endocannabinoid depletion by ABHD2 is a general mechanism by which progesterone exerts its genome-independent action and primes sperm for fertilization.	Progesterone	24-36	abhydrolase domain containing 2, acylglycerol lipase	Homo sapiens	76-81	
33752482-0	2021	Progesterone activates the cyclic AMP-protein kinase A signalling pathway by upregulating ABHD2 in fertile men.	Progesterone	0-12	abhydrolase domain containing 2, acylglycerol lipase	Homo sapiens	90-95	
33752482-1	2021	OBJECTIVE: This was a prospective study to investigate whether progesterone affects sperm activity by regulating the cyclic AMP-protein kinase A (cAMP-PKA) signalling pathway via alpha/beta hydrolase domain-containing protein 2 (ABHD2).	Progesterone	63-75	abhydrolase domain containing 2, acylglycerol lipase	Homo sapiens	179-227	
33752482-1	2021	OBJECTIVE: This was a prospective study to investigate whether progesterone affects sperm activity by regulating the cyclic AMP-protein kinase A (cAMP-PKA) signalling pathway via alpha/beta hydrolase domain-containing protein 2 (ABHD2).	Progesterone	63-75	abhydrolase domain containing 2, acylglycerol lipase	Homo sapiens	229-234	
33752482-4	2021	The expression of ABHD2 in the presence of progesterone was detected in all groups, and cAMP and PKA levels were detected by ELISA in fertile men after treatment with ABHD2 antibody and PKA inhibitor H-89, respectively.	Progesterone	43-55	abhydrolase domain containing 2, acylglycerol lipase	Homo sapiens	18-23	
33752482-7	2021	Progesterone increased mRNA and protein levels of ABHD2 in healthy spermatozoa but not in spermatozoa from infertile men.	Progesterone	0-12	abhydrolase domain containing 2, acylglycerol lipase	Homo sapiens	50-55	
33752482-8	2021	The levels of cAMP and PKA were increased by progesterone in healthy spermatozoa, and the progesterone-increased cAMP and PKA were decreased by ABHD2 antibody and H-89, respectively.	Progesterone	90-102	abhydrolase domain containing 2, acylglycerol lipase	Homo sapiens	144-149