PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12168772-1 2001 In rat islets, progesterone caused a prompt concentration-dependent inhibition of glucose-stimulated insulin release with an IC50 of 10 microM at 8.4mM glucose. Progesterone 15-27 insulin Mesocricetus auratus 101-108 12168772-10 2001 Thus blockade of Ca2+ entry appears to be the sole mechanism by which progesterone inhibits insulin release. Progesterone 70-82 insulin Mesocricetus auratus 92-99