PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17234720-9	2007	Taken together, the present study demonstrates that xanthorrhizol not only delays or inhibits tumor formation, but also reverses the carcinogenic process at pre-malignant stages by reducing the protein levels of ODC, iNOS and COX-2 regulated by the NF-kappaB, mitogen-activated protein kinases and/or Akt.	xanthorrhizol	52-65	thymoma viral proto-oncogene 1	Mus musculus	301-304	
17234720-8	2007	Furthermore, western blot analysis showed that xanthorrhizol suppressed the activation of extracellular signal-regulated protein kinase, p38, c-Jun-N-terminal kinase and Akt in mice after topical application for 6 weeks following the induction of papillomas.	xanthorrhizol	47-60	thymoma viral proto-oncogene 1	Mus musculus	170-173	
33683188-0	2021	Xanthorrhizol Suppresses Vascular Endothelial Growth Factor-Induced Angiogenesis by Modulating Akt/eNOS Signaling and the NF-[Formula: see text]B-Dependent Expression of Cell Adhesion Molecules.	xanthorrhizol	0-13	thymoma viral proto-oncogene 1	Mus musculus	95-98	
33683188-5	2021	Xanthorrhizol inhibited the phosphorylation of Akt and endothelial nitric oxide synthase (eNOS) and the expression of vascular cell adhesion molecule (VCAM)-1 and E-selectin in VEGF-treated HUVECs.	xanthorrhizol	0-13	thymoma viral proto-oncogene 1	Mus musculus	47-50	
33683188-10	2021	Taken together, xanthorrhizol inhibits VEGF-induced angiogenesis of endothelial cells by blocking the activation of the PI3K/Akt/eNOS axis and subsequent upregulation of adhesion molecules induced by the transcriptional activation of NF-[Formula: see text]B.	xanthorrhizol	16-29	thymoma viral proto-oncogene 1	Mus musculus	125-128