PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19189649-11 2008 These data suggest treatment with xanthorrhizol modulates MDA-MB-231 cell apoptosis through the mitochondria-mediated pathway subsequent to the disruption of mitochondrial transmembrane potential, release of cytochrome c, activation of caspase-3 and caspase-9, and the modulation of PARP-1 protein. xanthorrhizol 34-47 caspase 3 Homo sapiens 236-245 34664399-6 2022 In addition, XNT treatment alters the DeltaPsim, thereby induces apoptosis was closely coordinated with the induction of pro-apoptotic markers Bax, Bad, caspase- 3, 9 and cytochrome c, and suppression of anti-apoptotic (Bcl-2, Bcl-XL) protein expression. xanthorrhizol 13-16 caspase 3 Homo sapiens 153-163