PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19189649-11	2008	These data suggest treatment with xanthorrhizol modulates MDA-MB-231 cell apoptosis through the mitochondria-mediated pathway subsequent to the disruption of mitochondrial transmembrane potential, release of cytochrome c, activation of caspase-3 and caspase-9, and the modulation of PARP-1 protein.	xanthorrhizol	34-47	poly(ADP-ribose) polymerase 1	Homo sapiens	283-289	
22627996-2	2013	In this study, xanthorrhizol decreased cell viability, induced apoptosis and decreased the level of full-length PARP in SCC-15 oral squamous cell carcinoma (OSCC) cells.	xanthorrhizol	15-28	poly(ADP-ribose) polymerase 1	Homo sapiens	112-116	
19926935-8	2009	The apoptosis by xanthorrhizol was markedly evidenced by induction of DNA fragmentation, release of cytochrome c, activation of caspases, and cleavage of poly-(ADP-ribose) polymerase.	xanthorrhizol	17-30	poly(ADP-ribose) polymerase 1	Homo sapiens	154-182	
17201174-7	2006	The level of p53 was greatly increased, whilst PARP-1 was cleaved to 85 kDa subunits, following the treatment with xanthorrhizol at a dose-dependent manner.	xanthorrhizol	115-128	poly(ADP-ribose) polymerase 1	Homo sapiens	47-53	
17201174-8	2006	These results, thereby, suggest that xanthorrhizol has antiproliferative effects on MCF-7 cells by inducing apoptosis through the modulation of bcl-2, p53 and PARP-1 protein levels.	xanthorrhizol	37-50	poly(ADP-ribose) polymerase 1	Homo sapiens	159-165