PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34061162-0	2021	Remimazolam alleviates neuropathic pain via regulating bradykinin receptor B1 and autophagy.	remimazolam	0-11	bradykinin receptor B1	Rattus norvegicus	55-77	
34061162-3	2021	Considering the Bradykinin receptor"s vital role and the potentials of Bradykinin receptor B1 (BDKRB1) in the neuropathic pain-signalling pathway, we nominated them as a primary target for remimazolam.	remimazolam	189-200	bradykinin receptor B1	Rattus norvegicus	71-93	
34061162-3	2021	Considering the Bradykinin receptor"s vital role and the potentials of Bradykinin receptor B1 (BDKRB1) in the neuropathic pain-signalling pathway, we nominated them as a primary target for remimazolam.	remimazolam	189-200	bradykinin receptor B1	Rattus norvegicus	95-101	
34061162-8	2021	Moreover, remimazolam inactivated BDKRB1 signalling via suppressing NF-kappaB translocation and decreased the release of pro-inflammatory cytokines.	remimazolam	10-21	bradykinin receptor B1	Rattus norvegicus	34-40	
34061162-10	2021	However, R838 (an agonist of BDKRB1) reversed the effects of remimazolam.	remimazolam	61-72	bradykinin receptor B1	Rattus norvegicus	29-35	
34061162-11	2021	CONCLUSIONS: Remimazolam downregulated BDKRB1, inhibited BDKRB1/RAS/MEK signalling pathway and regulated the autophagic lysosome induction, exhibiting a better outcome in the NP.	remimazolam	13-24	bradykinin receptor B1	Rattus norvegicus	39-45	
34061162-11	2021	CONCLUSIONS: Remimazolam downregulated BDKRB1, inhibited BDKRB1/RAS/MEK signalling pathway and regulated the autophagic lysosome induction, exhibiting a better outcome in the NP.	remimazolam	13-24	bradykinin receptor B1	Rattus norvegicus	57-63