PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32057901-10	2020	Finally, we found that chemotherapy drug hydroxycamptothecin (HCPT) could decrease Arl4c expression levels by inhibiting the activation of the AKT pathway in A549 and 95-D cells.	10-hydroxycamptothecin	41-60	ADP ribosylation factor like GTPase 4C	Homo sapiens	83-88	
32057901-10	2020	Finally, we found that chemotherapy drug hydroxycamptothecin (HCPT) could decrease Arl4c expression levels by inhibiting the activation of the AKT pathway in A549 and 95-D cells.	10-hydroxycamptothecin	62-66	ADP ribosylation factor like GTPase 4C	Homo sapiens	83-88	
32057901-11	2020	Moreover, accumulation of ubiquitinated Arl4c protein was increased by HCPT and LY294002 (an AKT inhibitor) treatment whereas the proteasome inhibitor MG-132 attenuated the inhibitory effect of HCPT and LY294002 on Arl4c expression.	10-hydroxycamptothecin	71-75	ADP ribosylation factor like GTPase 4C	Homo sapiens	40-45	
32057901-12	2020	CONCLUSION: Here, we highlighted the AKT pathway as an important regulatory pathway for Arl4c expression in lung cancer cells and identified HCPT as a promising drug for lung adenocarcinoma treatment that functioned by targeting Arl4c expression.	10-hydroxycamptothecin	141-145	ADP ribosylation factor like GTPase 4C	Homo sapiens	88-93	
32057901-12	2020	CONCLUSION: Here, we highlighted the AKT pathway as an important regulatory pathway for Arl4c expression in lung cancer cells and identified HCPT as a promising drug for lung adenocarcinoma treatment that functioned by targeting Arl4c expression.	10-hydroxycamptothecin	141-145	ADP ribosylation factor like GTPase 4C	Homo sapiens	229-234