PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21435100-3 2011 In the present study we investigate the hypothesis that the unique water dispersible oleic acid-Triton X-100-coated Fe3O4 nanoparticles loaded with HCPT disrupt epithelial cell-cell junctions and induce human lung cancer cell apoptosis through the caspase-8 pathway. 10-hydroxycamptothecin 148-152 caspase 8 Homo sapiens 248-257 21435100-9 2011 Compared with void Fe3O4 nanoparticles or HCPT drug alone, HCPT drug-loaded nanoparticles evoked synergistic effects by increasing cell apoptosis with enhanced activation of the caspase-8 pathway. 10-hydroxycamptothecin 59-63 caspase 8 Homo sapiens 178-187