PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29577900-6 2018 Moreover, kenpaullone pretreatment significantly reduced ROS fluorescence intensity and significantly down-regulated the level of apoptosis-activating genes (cleaved caspase-3, cleaved caspase-9 and cytochrome C), autophagy markers (LC3A/B), and the Cx43-interacting partner SGSM3. kenpaullone 10-21 small G protein signaling modulator 3 Rattus norvegicus 275-280 29577900-7 2018 These results suggest that kenpaullone plays a role in protecting cardiomyocytes from oxidative stress and that the turnover of Cx43 through SGSM3-induced lysosomal degradation underlies the anti-apoptotic effect of kenpaullone. kenpaullone 216-227 small G protein signaling modulator 3 Rattus norvegicus 141-146 29577900-0 2018 Protective effects of kenpaullone on cardiomyocytes following H2O2-induced oxidative stress are attributed to inhibition of connexin 43 degradation by SGSM3. kenpaullone 22-33 small G protein signaling modulator 3 Rattus norvegicus 151-156 29577900-2 2018 Here, we investigated the protective effects of kenpaullone on cardiomyocytes following H2O2-induced oxidative stress mediated by the interaction of SGSM3 with Cx43. kenpaullone 48-59 small G protein signaling modulator 3 Rattus norvegicus 149-154