PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24900456-4	2012	In this letter, we describe the discovery of a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist (SAR 1118) and its development as an ophthalmic solution for treating dry eye.	1,2,3,4-tetrahydroisoquinoline	54-76	intercellular adhesion molecule 1	Homo sapiens	98-104	
24900456-4	2012	In this letter, we describe the discovery of a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist (SAR 1118) and its development as an ophthalmic solution for treating dry eye.	1,2,3,4-tetrahydroisoquinoline	78-82	intercellular adhesion molecule 1	Homo sapiens	98-104	
20655213-1	2010	This letter describes the discovery of a novel series of tetrahydroisoquinoline (THIQ)-derived small molecules that potently inhibit both human T-cell migration and super-antigen induced T-cell activation through disruption of the binding of integrin LFA-1 to its receptor, ICAM-1.	1,2,3,4-tetrahydroisoquinoline	57-79	intercellular adhesion molecule 1	Homo sapiens	274-280	
20655213-1	2010	This letter describes the discovery of a novel series of tetrahydroisoquinoline (THIQ)-derived small molecules that potently inhibit both human T-cell migration and super-antigen induced T-cell activation through disruption of the binding of integrin LFA-1 to its receptor, ICAM-1.	1,2,3,4-tetrahydroisoquinoline	81-85	intercellular adhesion molecule 1	Homo sapiens	274-280	
21109434-0	2011	Structure-activity relationship (SAR) of the alpha-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists.	1,2,3,4-tetrahydroisoquinoline	80-102	intercellular adhesion molecule 1	Homo sapiens	124-130	
21109434-0	2011	Structure-activity relationship (SAR) of the alpha-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists.	1,2,3,4-tetrahydroisoquinoline	104-108	intercellular adhesion molecule 1	Homo sapiens	124-130	
21109434-1	2011	This letter describes the structure-activity relationship (SAR) of the "right-wing" alpha-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists.	1,2,3,4-tetrahydroisoquinoline	119-141	intercellular adhesion molecule 1	Homo sapiens	163-169	
21109434-1	2011	This letter describes the structure-activity relationship (SAR) of the "right-wing" alpha-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists.	1,2,3,4-tetrahydroisoquinoline	143-147	intercellular adhesion molecule 1	Homo sapiens	163-169