PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33810348-0 2021 In Silico Design and Selection of New Tetrahydroisoquinoline-Based CD44 Antagonist Candidates. 1,2,3,4-tetrahydroisoquinoline 38-60 CD44 molecule (Indian blood group) Homo sapiens 67-71 34952427-9 2022 CCK-8 assay was used to show MTX-resistant CRC cell viability following CD44 inhibitor (THIQ) and AGT inhibitor (O6-BG) treatments. 1,2,3,4-tetrahydroisoquinoline 88-92 CD44 molecule (Indian blood group) Homo sapiens 72-76 34952427-15 2022 This research screened out CD44 and AGT in MTX-resistant CRC cells by bioinformatics and suggested that the combination of MTX with O6-BG or THIQ could enhance the sensitivity of MTX-resistant CRC cells to MTX. 1,2,3,4-tetrahydroisoquinoline 141-145 CD44 molecule (Indian blood group) Homo sapiens 27-31 31953176-4 2020 We observed that inhibition of CD44 by using 1,2,3,4 tetrahydroisoquinoline (THIQ) modulates the expression of Wnt/ beta-catenin signaling proteins and further silencing of beta-catenin also decreases the expression of CD44. 1,2,3,4-tetrahydroisoquinoline 45-75 CD44 molecule (Indian blood group) Homo sapiens 31-35