PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21109434-0 2011 Structure-activity relationship (SAR) of the alpha-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists. 1,2,3,4-tetrahydroisoquinoline 80-102 integrin subunit alpha L Homo sapiens 118-123 24900456-4 2012 In this letter, we describe the discovery of a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist (SAR 1118) and its development as an ophthalmic solution for treating dry eye. 1,2,3,4-tetrahydroisoquinoline 54-76 integrin subunit alpha L Homo sapiens 92-97 24900456-4 2012 In this letter, we describe the discovery of a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist (SAR 1118) and its development as an ophthalmic solution for treating dry eye. 1,2,3,4-tetrahydroisoquinoline 78-82 integrin subunit alpha L Homo sapiens 92-97 21109434-0 2011 Structure-activity relationship (SAR) of the alpha-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists. 1,2,3,4-tetrahydroisoquinoline 104-108 integrin subunit alpha L Homo sapiens 118-123 21109434-1 2011 This letter describes the structure-activity relationship (SAR) of the "right-wing" alpha-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists. 1,2,3,4-tetrahydroisoquinoline 119-141 integrin subunit alpha L Homo sapiens 157-162 21109434-1 2011 This letter describes the structure-activity relationship (SAR) of the "right-wing" alpha-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists. 1,2,3,4-tetrahydroisoquinoline 143-147 integrin subunit alpha L Homo sapiens 157-162