PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11131279-5	2000	Nitrite/nitrate (NOx) production stimulated by interleukin (IL)-1beta or tumor necrosis factor (TNF)-alpha in VSMCs was markedly suppressed by inhibiting MAP kinase by pretreatment with a p42/p44 MAP kinase kinase (MAPKK)-1 inhibitor (PD98059) or by transfecting the dominant-interfering form of the nonphosphorylated MAPKK-1 expressing construct (MAPKK S222A).	Nitrates	8-15	interleukin 1 beta	Rattus norvegicus	47-69	
29432804-11	2018	RESULTS: Nitrate supplementation in diabetic rats significantly improved glucose tolerance, lipid profiles, and catalase activity as well as decreased gluconeogenesis, fasting glucose, insulin, and IL-1beta; although it had no significant effect on GSIS, islet insulin content, HbA1c, and serum TBARS.	Nitrates	9-16	interleukin 1 beta	Rattus norvegicus	198-206	
11755929-4	2002	Both IL-1beta and TNF-alpha stimulated NF-kappaB activity, iNOS mRNA and protein expression with massive nitrite/nitrate (NOx) production in rat VSMCs.	Nitrates	113-120	interleukin 1 beta	Rattus norvegicus	5-13	
8904084-2	1996	Interleukin-1beta stimulated the production of nitrite and nitrate, stable metabolites of NO, in a dose- and time-dependent manner in vascular smooth muscle cells.	Nitrates	59-66	interleukin 1 beta	Rattus norvegicus	0-17	
7523451-3	1994	Treatment with IL-1 beta resulted in a marked increase in media nitrite and nitrate accumulation, morphological alterations, and increased release of lactate dehydrogenase (LDH) into media.	Nitrates	76-83	interleukin 1 beta	Rattus norvegicus	15-24	
10218970-4	1999	Both interleukin (IL)-1beta and tumor necrosis factor (TNF)-alpha potently stimulated nitrite/nitrate (NOx) production with a concomitant expression of iNOS mRNA and protein as demonstrated by Northern and Western blot analysis, respectively.	Nitrates	94-101	interleukin 1 beta	Rattus norvegicus	5-27	
9698594-9	1998	Both types of asbestos fibers also induced iNOS protein expression and the formation of nitrotyrosine in mesothelial cells and greatly induced the formation of nitrate (NO3-), a surrogate marker of ONOO- formation, in IL-1beta-stimulated cells.	Nitrates	160-167	interleukin 1 beta	Rattus norvegicus	218-226	
8760140-2	1996	Stimulation of rat pleural mesothelial cells with combinations of interleukin-1 beta (IL-1 beta), tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), and LPS induced the synthesis of nitric oxide as measured by the oxidation products nitrite (NO2-) and nitrate (NO3-).	Nitrates	272-279	interleukin 1 beta	Rattus norvegicus	66-84