PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26252500-0	2015	THB1 regulates nitrate reductase activity and THB1 and THB2 transcription differentially respond to NO and the nitrate/ammonium balance in Chlamydomonas.	Nitrates	15-22	uncharacterized protein	Chlamydomonas reinhardtii	0-4	
28032976-1	2017	Nitrate metabolism in Chlamydomonas reinhardtii involves THB1, a monomeric hemoglobin thought to function as a nitric oxide dioxygenase (NOD).	Nitrates	0-7	uncharacterized protein	Chlamydomonas reinhardtii	57-61	
26057801-2	2015	THB1 expression is under the control of NIT2, the master regulator of nitrate assimilation, which also controls the expression of the only nitrate reductase in the cell, NIT1.	Nitrates	70-77	uncharacterized protein	Chlamydomonas reinhardtii	0-4	
26057801-3	2015	In vitro and physiological evidence suggests that THB1 converts the nitric oxide generated by NIT1 into nitrate.	Nitrates	104-111	uncharacterized protein	Chlamydomonas reinhardtii	50-54	
26252500-12	2015	Thus, when cells are assimilating nitrate and NO appears (i.e. as a consequence of nitrite accumulation), THB1 has a double role: 1) to scavenge NO avoiding its toxic effects and 2) to control the nitrate reduction activity.	Nitrates	197-204	uncharacterized protein	Chlamydomonas reinhardtii	106-110	
29049377-9	2017	Thus, our data support the idea that in S-deprived cells THB1 plays a dual role in NO detoxification and in coordinating sulfate limitation with nitrate assimilation.	Nitrates	145-152	uncharacterized protein	Chlamydomonas reinhardtii	57-61	
25494936-6	2015	First, we found that THB1 and THB2 expression is modulated by the nitrogen source and depends on NIT2, a transcription factor required for nitrate assimilation genes expression.	Nitrates	139-146	uncharacterized protein	Chlamydomonas reinhardtii	21-25	
25494936-7	2015	Furthermore, THB1 is highly expressed in the presence of NO and is able to convert NO into nitrate in vitro.	Nitrates	91-98	uncharacterized protein	Chlamydomonas reinhardtii	13-17	
26252500-5	2015	THB1 and THB2 are regulated by the nitrogen source and respond differentially to NO and the nitrate/ammonium balance.	Nitrates	92-99	uncharacterized protein	Chlamydomonas reinhardtii	0-4	
26252500-7	2015	THB1 has NOD activity and thus a role in nitrate assimilation.	Nitrates	41-48	uncharacterized protein	Chlamydomonas reinhardtii	0-4	
26252500-8	2015	In fact, THB1 is upregulated by nitrate and is under the control of NIT2, the major transcription factor in nitrate assimilation.	Nitrates	32-39	uncharacterized protein	Chlamydomonas reinhardtii	9-13	
26252500-8	2015	In fact, THB1 is upregulated by nitrate and is under the control of NIT2, the major transcription factor in nitrate assimilation.	Nitrates	108-115	uncharacterized protein	Chlamydomonas reinhardtii	9-13	
26252500-12	2015	Thus, when cells are assimilating nitrate and NO appears (i.e. as a consequence of nitrite accumulation), THB1 has a double role: 1) to scavenge NO avoiding its toxic effects and 2) to control the nitrate reduction activity.	Nitrates	34-41	uncharacterized protein	Chlamydomonas reinhardtii	106-110