PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26641274-3	2016	We propose that the electron-withdrawing properties of -CHO and -COOH in 5fC and 5caC increase N3 acidity, leading to weakened hydrogen bonding and reduced base pair stability relative to C, 5mC, and 5hmC, thereby facilitating the selective recognition of 5fC and 5caC by TDG.	Hydrogen	127-135	thymine DNA glycosylase	Homo sapiens	272-275	
23337108-2	2013	In the previously solved structure of TDG in complex with DNA containing 5caC, the side chain of asparagine 157 (N157) contacts the 5-carboxyl moiety of 5caC via a weak hydrogen bond.	Hydrogen	169-177	thymine DNA glycosylase	Homo sapiens	38-41	
22962365-8	2012	TDG allows hydrogen-bonding interactions to both T/U-based (5hmU) and C-based (5caC) modifications, thus enabling its activity on a wider range of substrates.	Hydrogen	11-19	thymine DNA glycosylase	Homo sapiens	0-3	
20852254-8	2010	Molecular modeling and molecular dynamics simulations reveal distinct hydrogen-bonding patterns in the active site of E. coli MUG that account for the specificity differences between E. coli MUG and human thymine DNA glycosylase as well as that between the wild type MUG and the Asn-140 and Ser-23 mutants.	Hydrogen	70-78	thymine DNA glycosylase	Homo sapiens	205-228	
17965616-6	2006	DNA hypermethylation of TDG in the MM cell lines leads to lower gene expression levels that results in less efficient DNA repair activity in response to hydrogen peroxideinduced DNA damage.	Hydrogen	153-161	thymine DNA glycosylase	Homo sapiens	24-27