PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24531484-9 2014 This may suggest a clue to a possible ADP/GDP-release pathway, because the NE1 atom of the Trp in the `DWG motif" of CK2alpha forms a hydrogen bond to the O atom of Leu212, which seems to make ADP release by means of the `DFG-in flip to DFG-out" model found in most eukaryotic protein kinases impossible. Hydrogen 134-142 casein kinase 2 alpha 2 Homo sapiens 117-125 26974875-7 2016 In addition to the loss of the hydrogen bond between Gln36 of CK2alpha and Gly189 of Pc in the two mutants, the improper recognition mechanisms occurred through different pathways. Hydrogen 31-39 casein kinase 2 alpha 2 Homo sapiens 62-70 19796713-5 2010 In fully active CK2alpha the hinge region is open and does not anchor the ATP ribose, but alternatively it can adopt a closed conformation, form hydrogen bonds to the ribose moiety and thus retract the gamma-phospho group from its functional position. Hydrogen 145-153 casein kinase 2 alpha 2 Homo sapiens 16-24 19414254-2 2009 The inhibitor binds to CK2alpha with a novel binding mode, including water-mediated hydrogen bonds. Hydrogen 84-92 casein kinase 2 alpha 2 Homo sapiens 23-31