PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20600879-2 2010 The inhibition effect of macelignan on the CYP3A4-mediated metabolism was negligible over the concentration range of 0.01-100muM in rat liver microsome while approximately 33% inhibition was observed at 100muM in human liver microsome, implying that the interaction of macelignan with CYP3A4 might be insignificant at the physiologically achievable concentrations. macelignan 25-35 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 43-49 20600879-2 2010 The inhibition effect of macelignan on the CYP3A4-mediated metabolism was negligible over the concentration range of 0.01-100muM in rat liver microsome while approximately 33% inhibition was observed at 100muM in human liver microsome, implying that the interaction of macelignan with CYP3A4 might be insignificant at the physiologically achievable concentrations. macelignan 25-35 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 285-291