PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32359384-16 2020 However, treatment with macelignan significantly and dose-dependently down-regulated the expressions of bax and caspase-3 in these cells, but significantly and dose-dependently upregulated the expression of bcl-2. macelignan 24-34 caspase 3 Rattus norvegicus 112-121