PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21145457-0 2010 Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain. inositol pyrophosphates 0-23 thymoma viral proto-oncogene 1 Mus musculus 32-35 24670364-0 2014 Inositol pyrophosphates mediate the effects of aging on bone marrow mesenchymal stem cells by inhibiting Akt signaling. inositol pyrophosphates 0-23 thymoma viral proto-oncogene 1 Mus musculus 105-108 29111280-7 2019 Inositol pyrophosphates, synthesized by inositol hexakisphosphate (IP6) kinase 1 (IP6K1) and competitive with 3,4,5-bisphosphate (PIP3) to bind the PH domain of Akt/PKB, demonstrate the ability to inhibit Akt signaling. inositol pyrophosphates 0-23 thymoma viral proto-oncogene 1 Mus musculus 161-168 29111280-7 2019 Inositol pyrophosphates, synthesized by inositol hexakisphosphate (IP6) kinase 1 (IP6K1) and competitive with 3,4,5-bisphosphate (PIP3) to bind the PH domain of Akt/PKB, demonstrate the ability to inhibit Akt signaling. inositol pyrophosphates 0-23 thymoma viral proto-oncogene 1 Mus musculus 161-164