PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24568369-3 2014 Among these, the PLK1 inhibitor BI2536 and the JAK2 inhibitor TG101209 displayed strongest inhibitory potential against BRD4 (IC50=25 nM and 130 nM, respectively) and high selectivity for BET bromodomains. TG101209 62-70 bromodomain containing 4 Homo sapiens 120-124 28586718-2 2017 Interestingly, some kinase inhibitors have been demonstrated to be potent bromodomain inhibitors, especially the PLK1 inhibitor BI-2536 and the JAK2 inhibitor TG101209, which can bind to BRD4 with IC50 values of 0.025 muM and 0.13 muM, respectively. TG101209 159-167 bromodomain containing 4 Homo sapiens 187-191