PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14674691-1 2003 The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) has been shown to reversibly inhibit the activity of acetylcholinesterase. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 18-62 acetylcholinesterase (Cartwright blood group) Homo sapiens 123-143 14674691-1 2003 The neurotoxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) has been shown to reversibly inhibit the activity of acetylcholinesterase. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 64-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 123-143 14674691-7 2003 The dilution assays indicate that MPTP is a reversible inhibitor for AChE. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 34-38 acetylcholinesterase (Cartwright blood group) Homo sapiens 69-73 14674691-8 2003 These data suggest that once MPTP enters the basal ganglia of the brain, it can inactivate the acetylcholinesterase enzyme and thereby increase the acetylcholine level in the basal ganglia of brain, leading to potential cell dysfunction. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 29-33 acetylcholinesterase (Cartwright blood group) Homo sapiens 95-115 14674691-9 2003 It appears that the nigrostriatal toxicity by MPTP leading to Parkinson"s disease-like syndrome may, in part, be mediated via the acetylcholinesterase inactivation. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 46-50 acetylcholinesterase (Cartwright blood group) Homo sapiens 130-150 8302294-0 1993 Acetylcholinesterase inhibition by 1-methyl-4-phenylpyridinium ion, a bioactivated metabolite of MPTP. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 97-101 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20