PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32386222-8	2020	The CPO-A treatment attenuated or restored (P < 0.05) these changes and inhibited (P < 0.05) the MPTP-induced activation of P38 mitogen-activated protein kinase (P38MAPK) and P53, along with the downstream expression of BCL-2 associated X protein (BAX) in the SN.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	97-101	tumor protein p53	Homo sapiens	175-178	
29769744-7	2019	Taken together, NADPH abrogated MPTP-induced p38MAPK phosphorylation, TP53 nuclear translocation, and Bax induction, and finally, MPTP/MPP+-induced apoptosis of DA neurons.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	32-36	tumor protein p53	Homo sapiens	70-74	
12358742-0	2002	A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	68-72	tumor protein p53	Homo sapiens	51-54	
29498006-7	2018	Furthermore, nimesulide with MPTP increased apoptotic protein cleaved caspase-3 and also induced expression of p53 gene.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	29-33	tumor protein p53	Homo sapiens	111-114	
18266926-4	2008	We recently reported that PQ induces neuronal apoptosis through Bak activation, in contrast to MPP(+), the toxic metabolite of MPTP, which relies on Bax and p53.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	127-131	tumor protein p53	Homo sapiens	157-160	
12358742-5	2002	p53 is a target of the nuclear enzyme Poly(ADP-ribose)polymerase (PARP), and PARP is activated following DNA damage that occurs following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	138-182	tumor protein p53	Homo sapiens	0-3	
12358742-5	2002	p53 is a target of the nuclear enzyme Poly(ADP-ribose)polymerase (PARP), and PARP is activated following DNA damage that occurs following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	184-188	tumor protein p53	Homo sapiens	0-3	
12358742-8	2002	We find that p53 is heavily poly(ADP-ribosyl)ated by PARP-1 following MPTP intoxication.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	70-74	tumor protein p53	Homo sapiens	13-16	
12358742-10	2002	These influences of PARP-1 on p53 may underlie the mechanisms of MPTP-induced parkinsonism and other models of neuronal death.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	65-69	tumor protein p53	Homo sapiens	30-33