PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22821000-0	2012	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	170-214	RAN binding protein 2	Mus musculus	0-6	
22821000-0	2012	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	216-220	RAN binding protein 2	Mus musculus	0-6	
22821000-4	2012	MPTP led to stronger akinetic parkinsonism and slower recovery in Ranbp2                         (+/-) than wild-type mice without viability changes of brain TH(+)-neurons of either genotype, with the exception of transient nuclear atypia via changes in chromatin condensation of Ranbp2                         (+/-) TH(+)-neurons.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	0-4	RAN binding protein 2	Mus musculus	66-72	
22821000-4	2012	MPTP led to stronger akinetic parkinsonism and slower recovery in Ranbp2                         (+/-) than wild-type mice without viability changes of brain TH(+)-neurons of either genotype, with the exception of transient nuclear atypia via changes in chromatin condensation of Ranbp2                         (+/-) TH(+)-neurons.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	0-4	RAN binding protein 2	Mus musculus	280-286	
22821000-7	2012	Finally, MPTP-treated wild-type and Ranbp2                         (+/-) mice present distinct metabolic footprints in the brain or selective regions thereof, such as striatum, that are supportive of RanBP2-mediated regulation of interdependent metabolic pathways of lysine, cholesterol, free-fatty acids, or their beta-oxidation.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	9-13	RAN binding protein 2	Mus musculus	36-42	
22821000-7	2012	Finally, MPTP-treated wild-type and Ranbp2                         (+/-) mice present distinct metabolic footprints in the brain or selective regions thereof, such as striatum, that are supportive of RanBP2-mediated regulation of interdependent metabolic pathways of lysine, cholesterol, free-fatty acids, or their beta-oxidation.	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine	9-13	RAN binding protein 2	Mus musculus	200-206