PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28498365-5 2017 However, downregulation of endogenous Chk2 by siRNA as well as Chk2 selective inhibitor PV1019 implies that 4DPG-mediated inhibition of Twist1 is Chk2-dependent. 4dpg 108-112 checkpoint kinase 2 Mus musculus 38-42 28498365-4 2017 In addition, ectopic Chk2, as well as its (Chk2) induction by natural podophyllotoxin analog, 4"-demethyl-deoxypodophyllotoxin glucoside (4DPG), strongly restrain Twist1 activity along with other mesenchymal markers, for example, ZEB-1, vimentin and Snail1, whereas the epithelial markers such as E-cadherin and TIMP-1 expression augmented robustly. 4dpg 138-142 checkpoint kinase 2 Mus musculus 43-47 28498365-5 2017 However, downregulation of endogenous Chk2 by siRNA as well as Chk2 selective inhibitor PV1019 implies that 4DPG-mediated inhibition of Twist1 is Chk2-dependent. 4dpg 108-112 checkpoint kinase 2 Mus musculus 63-67 28498365-5 2017 However, downregulation of endogenous Chk2 by siRNA as well as Chk2 selective inhibitor PV1019 implies that 4DPG-mediated inhibition of Twist1 is Chk2-dependent. 4dpg 108-112 checkpoint kinase 2 Mus musculus 63-67