PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30459602-10 2018 The further mechanism researches indicated that psoralen-induced hepatotoxicity was associated with inhibition of mTOR signalling pathway and mitochondrial injury; furthermore, MHY, an mTOR activator, partly alleviated the inhibition of mTOR and S-phase cycle arrest induced by psoralen in L02 cells. Ficusin 48-56 mechanistic target of rapamycin kinase Homo sapiens 114-118 35597499-13 2022 In summary, we speculated that when psoralen causes hepatotoxicity, it acts on the direct target ABL1, resulting in a decrease in Nrf2 expression, an increase in ROS levels and a reduction in mTOR expression, which may cause cell death. Ficusin 36-44 mechanistic target of rapamycin kinase Homo sapiens 192-196 30459602-10 2018 The further mechanism researches indicated that psoralen-induced hepatotoxicity was associated with inhibition of mTOR signalling pathway and mitochondrial injury; furthermore, MHY, an mTOR activator, partly alleviated the inhibition of mTOR and S-phase cycle arrest induced by psoralen in L02 cells. Ficusin 48-56 mechanistic target of rapamycin kinase Homo sapiens 185-189 30459602-10 2018 The further mechanism researches indicated that psoralen-induced hepatotoxicity was associated with inhibition of mTOR signalling pathway and mitochondrial injury; furthermore, MHY, an mTOR activator, partly alleviated the inhibition of mTOR and S-phase cycle arrest induced by psoralen in L02 cells. Ficusin 48-56 mechanistic target of rapamycin kinase Homo sapiens 185-189