PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18435621-1 2008 A triplex-forming oligonucleotide (TFO), HPRT3, conjugated to a psoralen derivative, was designed to target a psoralen reaction site within the HPRT gene. Ficusin 64-72 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 41-45 1685031-2 1991 We previously reported that after photoaddition of psoralen derivatives the frequency of HPRT- mutants was significantly lower in FA than in normal human lymphoblasts. Ficusin 51-59 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 89-93 1685031-6 1991 In normal cells, the minority of spontaneous (31%) and psoralen-induced mutants (0% and 14% according to treatment) arise from mutations that alter the HPRT gene transcription. Ficusin 55-63 hypoxanthine phosphoribosyltransferase 1 Homo sapiens 152-156