PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22841414-0 2012 Evolution of microglial activation in ischaemic core and peri-infarct regions after stroke: a PET study with the TSPO molecular imaging biomarker [((11))C]vinpocetine. vinpocetine 155-166 translocator protein Homo sapiens 113-117 22841414-7 2012 The present observations demonstrate that increased regional microglia activation, as a consequence of stroke, can be visualised with PET, using the TSPO molecular imaging biomarker [((11))C]vinpocetine. vinpocetine 191-202 translocator protein Homo sapiens 149-153 21320609-0 2011 Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine. vinpocetine 146-157 translocator protein Homo sapiens 39-59 21320609-0 2011 Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine. vinpocetine 146-157 translocator protein Homo sapiens 61-65 21320609-10 2011 CONCLUSIONS: The present data indicate that [(11)C]vinpocetine may serve as a molecular imaging biomarker of the activity of the TSPO system and, consequently, of the up-regulation of microglia during ageing and in neuroinflammatory diseases. vinpocetine 51-62 translocator protein Homo sapiens 129-133 21320609-13 2011 For this reason, PET studies using [(11)C]vinpocetine, as molecular imaging biomarker, can efficiently visualise the activation of microglia and the up-regulation of TSPO during ageing and in diseased brains with the help of an appropriate inhomogeneity analysis of the radioligand"s brain uptake pattern. vinpocetine 42-53 translocator protein Homo sapiens 166-170