PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20381862-7 2010 Compared to SPIO, USPIO induced more pronounced biochemical alterations and cytotoxicity, which could be antagonized by the JNK inhibitor V. Alternatively, treatment of macrophages with Trolox or N-acetyl-L-cysteine, two functionally different scavengers of reactive oxygen species, abolished both the JNK activation and the subsequent cytotoxic effects. ferumoxtran-10 18-23 mitogen-activated protein kinase 8 Homo sapiens 124-127 20381862-7 2010 Compared to SPIO, USPIO induced more pronounced biochemical alterations and cytotoxicity, which could be antagonized by the JNK inhibitor V. Alternatively, treatment of macrophages with Trolox or N-acetyl-L-cysteine, two functionally different scavengers of reactive oxygen species, abolished both the JNK activation and the subsequent cytotoxic effects. ferumoxtran-10 18-23 mitogen-activated protein kinase 8 Homo sapiens 302-305