PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25298341-4 2014 Vasopressin is the major hormone in vivo that rapidly increases urea permeability in the IMCD through increases in phosphorylation and apical plasma-membrane accumulation of UT-A1. Urea 64-68 arginine vasopressin Homo sapiens 0-11 21178107-1 2011 During antidiuresis with elevated vasopressin, urea accumulates in the renal medulla to very high concentrations, imposing considerable cellular stress. Urea 47-51 arginine vasopressin Homo sapiens 34-45 22962322-9 2012 The vasopressin (+) group had higher urea and creatinine levels. Urea 37-41 arginine vasopressin Homo sapiens 4-15 22673023-3 2012 METHODS: In a subset analysis of the Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan trial, 759 patients (18% of total) had elevated blood urea nitrogen (BUN) (> 20 mg/dl) and low SBP (<105 mmHg) at admission. Urea 172-176 arginine vasopressin Homo sapiens 49-60 22332827-6 2012 Urea in the dialysate increased from a baseline of 7.9 +- 1.7 to 10.9 +- 0.9 mmol/L for the highest concentration of NE (p < 0.001) and from 8.1 +- 1.4 to 10.0 +- 1.7 mmol/L for the highest concentration of VP (p = 0.037). Urea 0-4 arginine vasopressin Homo sapiens 210-212 21672011-0 2012 Inappropriate antidiuretic hormone secretion: long-term successful urea treatment. Urea 67-71 arginine vasopressin Homo sapiens 14-34 21686211-0 2011 Regulation of renal urea transport by vasopressin. Urea 20-24 arginine vasopressin Homo sapiens 38-49 21686211-5 2011 Vasopressin rapidly increases water and urea transport in the terminal inner medullary collecting duct (IMCD). Urea 40-44 arginine vasopressin Homo sapiens 0-11 21686211-6 2011 Vasopressin rapidly increases urea permeability in the IMCD through increases in phosphorylation and apical plasma-membrane accumulation of the urea transporter A1 (UT-A1). Urea 30-34 arginine vasopressin Homo sapiens 0-11 21686211-9 2011 In summary, vasopressin regulates urea transport acutely by increasing UT-A1 phosphorylation and the apical plasma-membrane accumulation of UT-A1 through two cAMP-dependent pathways. Urea 34-38 arginine vasopressin Homo sapiens 12-23 19052101-4 2009 Within 10 min, vasopressin stimulates urea flux through UT-A3 transporters already present at the plasma membrane, via a PKA-dependent process. Urea 38-42 arginine vasopressin Homo sapiens 15-26 19011892-0 2009 Essential role of vasopressin-regulated urea transport processes in the mammalian kidney. Urea 40-44 arginine vasopressin Homo sapiens 18-29 19052101-5 2009 Within 1 h, vasopressin significantly increases UT-A3 localization at the basolateral membrane, causing a further increase in urea transport. Urea 126-130 arginine vasopressin Homo sapiens 12-23 19052101-7 2009 In conclusion, this study details the effects of vasopressin on UT-A3 urea transporter function and hence its role in regulating urea permeability within the renal inner medullary collecting duct. Urea 70-74 arginine vasopressin Homo sapiens 49-60 10795928-6 2000 UT-A1 is localised in the terminal part of the inner medullary collecting ducts and accounts for the vasopressin-dependent increase in urea permeability of this segment. Urea 135-139 arginine vasopressin Homo sapiens 101-112 15143132-5 2004 The conundrum for the excretion of urea focuses on the fact that urea is not an effective osmole in the medullary-collecting duct when vasopressin acts. Urea 35-39 arginine vasopressin Homo sapiens 135-146 12194010-5 2002 Other genes include the vasopressin-regulated urea transporters that play a key role in building up high urea concentrations in the renal medulla during antidiuresis and a heat shock protein 70 that protects cells from the deadly effects of urea. Urea 46-50 arginine vasopressin Homo sapiens 24-35 12194010-5 2002 Other genes include the vasopressin-regulated urea transporters that play a key role in building up high urea concentrations in the renal medulla during antidiuresis and a heat shock protein 70 that protects cells from the deadly effects of urea. Urea 105-109 arginine vasopressin Homo sapiens 24-35 10795928-11 2000 Vasopressin, upon binding to V2 receptors in the inner medullary collecting ducts, increases urea permeability through activation of UT-A1 molecules, thus enabling urea to diffuse into the inner medullary interstitium. Urea 93-97 arginine vasopressin Homo sapiens 0-11 10795928-11 2000 Vasopressin, upon binding to V2 receptors in the inner medullary collecting ducts, increases urea permeability through activation of UT-A1 molecules, thus enabling urea to diffuse into the inner medullary interstitium. Urea 164-168 arginine vasopressin Homo sapiens 0-11 10795928-15 2000 The acute direct and delayed indirect actions of vasopressin on renal urea transporters will increase medullary urea accumulation and thus the ability of the kidney to conserve water. Urea 70-74 arginine vasopressin Homo sapiens 49-60 10795928-16 2000 Atrial natriuretic peptide inhibits the vasopressin-dependent increase in urea permeability in the inner medullary collecting ducts. Urea 74-78 arginine vasopressin Homo sapiens 40-51 9189853-1 1997 Antidiuretic hormone leads to an increase in the permeability for water and urea in the inner medullary collecting duct. Urea 76-80 arginine vasopressin Homo sapiens 0-20 9822114-1 1998 Traditionally, arginine vasopressin modulation of renal water, sodium, and urea excretion has been considered somewhat in isolation from factors that control divalent mineral ion homeostasis. Urea 75-79 arginine vasopressin Homo sapiens 24-35 9575638-4 1998 The increase in urea excretion may be associated with a reduction of urea reabsorption at the collecting duct as a consequence of ADH suppression. Urea 16-20 arginine vasopressin Homo sapiens 130-133 9374816-13 1997 The less efficient sodium excretion occurring at low V is probably due to the influence of vasopressin on water, urea, and sodium movements across the collecting ducts. Urea 113-117 arginine vasopressin Homo sapiens 91-102 9043798-18 1997 Four sequences are known for urea transporters HUT11-the urea transporter of the human red cell membrane, and HUT2, rUT2, rbUT2-the arginine vasopressin inducible urea transporters of the human, rat and rabbit kidney. Urea 29-33 arginine vasopressin Homo sapiens 141-152 8540707-7 1995 Urea transport induced by a maximal dose of ADH (24 mIU/ml) was inhibited by 0.1 to 5.0 mM foscarnet. Urea 0-4 arginine vasopressin Homo sapiens 44-47 8525143-4 1995 Vasopressin-dependent urea recycling and delivery to the thick ascending limb could similarly reduce NaCl concentration at the macula densa. Urea 22-26 arginine vasopressin Homo sapiens 0-11 7620857-1 1995 In the vasopressin-stimulated inner medullary collecting duct (IMCD), urea is transported through a pathway which is distinct from a water channel. Urea 70-74 arginine vasopressin Homo sapiens 7-18 8590215-3 1995 The stimulation by cyclic AMP of sodium chloride reabsorption in the thick ascending limb, and of urea reabsorption in the papillary collecting duct indicates that vasopressin--in addition to its well known hydroosmotic effect--also participates in the building up of the corticopapillary gradient of osmotic pressure. Urea 98-102 arginine vasopressin Homo sapiens 164-175 2075636-1 1990 Dehydrated patients usually present with an elevated serum urea level, owing in part to increased renal reabsorption of urea mediated by antidiuretic hormone (ADH). Urea 59-63 arginine vasopressin Homo sapiens 137-157 8305636-6 1993 A possible mechanism is proposed that could explain how the vasopressin-induced intrarenal recycling of urea (which contributes to improvement in urinary concentration), but not an exogenous urea administration, could indirectly depress the tubuloglomerular feedback and hence increase GFR. Urea 104-108 arginine vasopressin Homo sapiens 60-71 8465115-3 1993 Urea in the terminal IMCD is transported by a specific urea transporter that is stimulated by vasopressin and hyperosmolarity. Urea 0-4 arginine vasopressin Homo sapiens 94-105 7875032-0 1994 Urea transport in frog oocytes: effect of osmotic stress and vasopressin. Urea 0-4 arginine vasopressin Homo sapiens 61-72 7875032-2 1994 While vasopressin responsiveness correlates with increased urea/water permeability in some epithelia, oocytes provide a single cell system to determine the coupling relationship. Urea 59-63 arginine vasopressin Homo sapiens 6-17 8396343-0 1993 Kinetic model of water and urea permeability regulation by vasopressin in collecting duct. Urea 27-31 arginine vasopressin Homo sapiens 59-70 8396343-1 1993 We present a mathematical model describing the kinetics of water-channel and urea-carrier regulation by vasopressin in the apical membrane of collecting duct cells. Urea 77-81 arginine vasopressin Homo sapiens 104-115 1525481-1 1992 We previously reported that HgCl2 inhibits water and urea flux in tissues fixed with glutaraldehyde after antidiuretic hormone (ADH) stimulation and suggested that the ADH-induced water channel may share characteristics of the red blood cell and proximal tubule water transport pathway. Urea 53-57 arginine vasopressin Homo sapiens 168-171 2075636-1 1990 Dehydrated patients usually present with an elevated serum urea level, owing in part to increased renal reabsorption of urea mediated by antidiuretic hormone (ADH). Urea 59-63 arginine vasopressin Homo sapiens 159-162 2075636-1 1990 Dehydrated patients usually present with an elevated serum urea level, owing in part to increased renal reabsorption of urea mediated by antidiuretic hormone (ADH). Urea 120-124 arginine vasopressin Homo sapiens 137-157 2075636-1 1990 Dehydrated patients usually present with an elevated serum urea level, owing in part to increased renal reabsorption of urea mediated by antidiuretic hormone (ADH). Urea 120-124 arginine vasopressin Homo sapiens 159-162 2075636-8 1990 Therefore, our results suggest that serum urea values can be used to distinguish patients dehydrated because of CDI from those with hypertonic dehydration but without ADH deficiency and that during dehydration the reabsorption of urea is mainly dependent on the renal action of ADH. Urea 42-46 arginine vasopressin Homo sapiens 167-170 2162269-0 1990 Dissociation between uric acid and urea clearances in the syndrome of inappropriate secretion of antidiuretic hormone related to salt excretion. Urea 35-39 arginine vasopressin Homo sapiens 97-117 2204274-1 1990 The terminal part of the inner medullary collecting duct (terminal IMCD) is unique among collecting duct segments in part because its permeability to urea is regulated by vasopressin. Urea 150-154 arginine vasopressin Homo sapiens 171-182 2204274-2 1990 The urea permeability can rise to extremely high levels (greater than 100 x 10(-5) cm/s) in response to vasopressin. Urea 4-8 arginine vasopressin Homo sapiens 104-115 2204274-4 1990 This urea transporter has properties similar to those of the urea transporters in mammalian erythrocytes and in toad urinary bladder, namely, inhibition by phloretin, inhibition by urea analogues, saturation kinetics in equilibrium-exchange experiments, and regulation by vasopressin. Urea 5-9 arginine vasopressin Homo sapiens 272-283 2204274-6 1990 The increase in transepithelial urea transport in response to vasopressin is mediated by adenosine 3",5"-cyclic monophosphate and is associated with an increase in the urea permeability of the apical membrane. Urea 32-36 arginine vasopressin Homo sapiens 62-73 2204274-6 1990 The increase in transepithelial urea transport in response to vasopressin is mediated by adenosine 3",5"-cyclic monophosphate and is associated with an increase in the urea permeability of the apical membrane. Urea 168-172 arginine vasopressin Homo sapiens 62-73 2162269-7 1990 In the syndrome of inappropriate secretion of antidiuretic hormone, the fractional excretion of filtered urea was inversely correlated to the fractional excretion of filtered sodium (r = -0.66; P less than 0.001), whereas the fractional excretion of filtered uric acid was not dependent on sodium excretion. Urea 105-109 arginine vasopressin Homo sapiens 46-66 2162269-9 1990 Hypouraemia with high fractional excretion of filtered urea in patients with the syndrome of inappropriate secretion of antidiuretic hormone is related to low urinary sodium excretion and thus reflects low sodium intake. Urea 55-59 arginine vasopressin Homo sapiens 120-140 2964201-2 1988 When studied in vitro, ADH antagonists displace vasopressin from specific renal binding sites and antagonize, in a competitive fashion, vasopressin stimulation of adenylate cyclase and transepithelial water, salt, and urea fluxes. Urea 218-222 arginine vasopressin Homo sapiens 23-26 2488758-0 1989 Vasopressin-induced changes in permeability of peritoneal mesothelium for urea "in vitro". Urea 74-78 arginine vasopressin Homo sapiens 0-11 1970914-2 1990 In patients with oliguria there was a significant activation of RAS, an increase in plasma vasopressin ad osmolality due to the increment of the urea in presence of hyponatremia. Urea 145-149 arginine vasopressin Homo sapiens 91-102 3179869-1 1988 Dehydrated patients usually present with an elevated serum urea level, owing in part to increased renal reabsorption of urea mediated by antidiuretic hormone (ADH). Urea 59-63 arginine vasopressin Homo sapiens 137-157 3179869-1 1988 Dehydrated patients usually present with an elevated serum urea level, owing in part to increased renal reabsorption of urea mediated by antidiuretic hormone (ADH). Urea 59-63 arginine vasopressin Homo sapiens 159-162 3179869-1 1988 Dehydrated patients usually present with an elevated serum urea level, owing in part to increased renal reabsorption of urea mediated by antidiuretic hormone (ADH). Urea 120-124 arginine vasopressin Homo sapiens 137-157 3179869-1 1988 Dehydrated patients usually present with an elevated serum urea level, owing in part to increased renal reabsorption of urea mediated by antidiuretic hormone (ADH). Urea 120-124 arginine vasopressin Homo sapiens 159-162 3179869-7 1988 In the patients with CDI the serum urea level returned to the level before dehydration after the administration of vasopressin; a striking increase in the clearance of urea, which exceeded the creatinine clearance, was observed during dehydration in the three patients in whom clearance studies were done. Urea 35-39 arginine vasopressin Homo sapiens 115-126 3179869-7 1988 In the patients with CDI the serum urea level returned to the level before dehydration after the administration of vasopressin; a striking increase in the clearance of urea, which exceeded the creatinine clearance, was observed during dehydration in the three patients in whom clearance studies were done. Urea 168-172 arginine vasopressin Homo sapiens 115-126 3179869-8 1988 The results suggest that serum urea values can be used to distinguish patients dehydrated because of CDI from those with hypertonic dehydration but without ADH deficiency and that during dehydration the net reabsorption of urea is dependent on the renal action of ADH. Urea 31-35 arginine vasopressin Homo sapiens 156-159 2964201-2 1988 When studied in vitro, ADH antagonists displace vasopressin from specific renal binding sites and antagonize, in a competitive fashion, vasopressin stimulation of adenylate cyclase and transepithelial water, salt, and urea fluxes. Urea 218-222 arginine vasopressin Homo sapiens 136-147 2964201-5 1988 Other renal responses associated with administration of ADH antagonists include changes in renal hemodynamics and renal salt and urea excretion. Urea 129-133 arginine vasopressin Homo sapiens 56-59 3114713-1 1987 Gossypol, a polyphenol compound with antifertility properties in human male, has been found to interfere with the response of toad bladder to vasopressin in terms of permeability to water and to urea; on the other hand, ion movement is spared for several hours as judged from short-circuit current and conductance data. Urea 195-199 arginine vasopressin Homo sapiens 142-153 3688238-0 1987 Vasopressin effects on urea and H2O transport in inner medullary collecting duct subsegments. Urea 23-27 arginine vasopressin Homo sapiens 0-11 3688238-8 1987 The results support the premise that (from the point of view of vasopressin effects on water and urea transport) there are two functionally distinct parts of the inner medullary collecting duct: an initial part that resembles the cortical or outer medullary portions of the mammalian collecting duct and a terminal part that resembles the toad urinary bladder. Urea 97-101 arginine vasopressin Homo sapiens 64-75 3079963-8 1986 Average values (+/- SE) for induction of a half-maximal urea permeability response in toads from all seasons were 1.4 +/- 0.3 X 10(-10) M for AVT, 7.4 +/- 1.5 X 10(-9) M for 8-arginine vasopressin, and 2.9 +/- 0.6 X 10(-8) M for oxytocin. Urea 56-60 arginine vasopressin Homo sapiens 185-196 3030272-2 1986 In hepatocytes, urea synthesis from glutamine is independent of added ornithine, even when rates are high after stimulation of glutamine metabolism by dibutyryl cyclic AMP, phenylephrine or vasopressin. Urea 16-20 arginine vasopressin Homo sapiens 190-201 3006506-1 1986 Binding of tritium-labeled vasopressin [( 3H]AVP) to a broken epithelial cell preparation of the toad"s urinary bladder has been related to hormonal action on water and urea transport across the intact tissue. Urea 169-173 arginine vasopressin Homo sapiens 27-38 3006506-1 1986 Binding of tritium-labeled vasopressin [( 3H]AVP) to a broken epithelial cell preparation of the toad"s urinary bladder has been related to hormonal action on water and urea transport across the intact tissue. Urea 169-173 arginine vasopressin Homo sapiens 45-48 3006506-3 1986 Half-maximal urea and water permeability responses were observed with 3.1 and 5.6 nM AVP, respectively, although half-maximal receptor saturation required considerably higher concentrations of hormone (less than 500 nM). Urea 13-17 arginine vasopressin Homo sapiens 85-88 6407333-7 1983 With urea, the correlation between plasma osmolality and vasopressin was significantly lower. Urea 5-9 arginine vasopressin Homo sapiens 57-68 2434767-1 1986 Vasopressin increases the permeability of responsive epithelia for a variety of chemical species, such as sodium, urea, water, and lipophilic molecules. Urea 114-118 arginine vasopressin Homo sapiens 0-11 2434773-3 1986 The mechanisms whereby vasopressin could enhance interstitial tonicity include increasing urea permeability in the inner medullary collecting tubule, stimulation of solute reabsorption in the thick ascending limb of the loop of Henle, increasing the glomerular filtration rate of juxtamedullary nephrons, and decreasing vasa recta blood flow. Urea 90-94 arginine vasopressin Homo sapiens 23-34 3927055-3 1985 We have shown a significant increase in 14C urea entry into epithelial cells following vasopressin, and a significant decrease following phloretin, an agent that selectively blocks vasopressin-stimulated urea transport. Urea 44-48 arginine vasopressin Homo sapiens 87-98 3920247-0 1985 Roles of Ca2+ and Na+ on the modulation of antidiuretic hormone action on urea permeability in toad urinary bladder. Urea 74-78 arginine vasopressin Homo sapiens 43-63 3920247-1 1985 The present studies probe the role of Ca2+ and Na+ in the stimulation-permeability coupling sequences by which antidiuretic hormone (ADH) induces a cyclic AMP (cAMP)-mediated increase in urea permeability in toad urinary bladder. Urea 187-191 arginine vasopressin Homo sapiens 111-131 3920247-1 1985 The present studies probe the role of Ca2+ and Na+ in the stimulation-permeability coupling sequences by which antidiuretic hormone (ADH) induces a cyclic AMP (cAMP)-mediated increase in urea permeability in toad urinary bladder. Urea 187-191 arginine vasopressin Homo sapiens 133-136 3920247-13 1985 (b) Increases in cytosolic Ca2+ activity, which are capable of inhibiting the effect of ADH on urea permeability at pre- and/or post-cAMP steps, seem to be highly compartmentalized. Urea 95-99 arginine vasopressin Homo sapiens 88-91 6601721-6 1983 These results, together with previous observations indicating that other small molecules (like urea) are excluded from the ADH-induced channel, might indicate that single-file water movement can occur through this structure. Urea 95-99 arginine vasopressin Homo sapiens 123-126 6408646-1 1983 Toad bladders exposed to vasopressin (ADH) and then fixed on the mucosal surface with 1% glutaraldehyde were highly permeable to water and to urea compared to control bladders fixed in the absence of hormone. Urea 142-146 arginine vasopressin Homo sapiens 25-36 6165739-4 1981 In contrast to water flow, vasopressin-stimulated urea permeability was decreased by aprotinin and increased by captopril. Urea 50-54 arginine vasopressin Homo sapiens 27-38 6807102-0 1982 Importance of molecular size and hydrogen bonding in vasopressin-stimulated urea transport. Urea 76-80 arginine vasopressin Homo sapiens 53-64 6807102-1 1982 We have employed a variety of urea and thiourea analogues to elucidate further the vasopressin-stimulated urea transport mechanism. Urea 30-34 arginine vasopressin Homo sapiens 83-94 6807102-1 1982 We have employed a variety of urea and thiourea analogues to elucidate further the vasopressin-stimulated urea transport mechanism. Urea 43-47 arginine vasopressin Homo sapiens 83-94 6807102-10 1982 This model can account for the selectivity of the vasopressin-stimulated urea transport, its inhibition by urea and thiourea analogues, the facilitated transport of urea, inhibition of tracer urea flux from either the cis or the trans position, and finally the preservation of the urea transport machinery following glutaraldehyde fixation. Urea 73-77 arginine vasopressin Homo sapiens 50-61 6807102-10 1982 This model can account for the selectivity of the vasopressin-stimulated urea transport, its inhibition by urea and thiourea analogues, the facilitated transport of urea, inhibition of tracer urea flux from either the cis or the trans position, and finally the preservation of the urea transport machinery following glutaraldehyde fixation. Urea 107-111 arginine vasopressin Homo sapiens 50-61 6807102-10 1982 This model can account for the selectivity of the vasopressin-stimulated urea transport, its inhibition by urea and thiourea analogues, the facilitated transport of urea, inhibition of tracer urea flux from either the cis or the trans position, and finally the preservation of the urea transport machinery following glutaraldehyde fixation. Urea 107-111 arginine vasopressin Homo sapiens 50-61 6807102-10 1982 This model can account for the selectivity of the vasopressin-stimulated urea transport, its inhibition by urea and thiourea analogues, the facilitated transport of urea, inhibition of tracer urea flux from either the cis or the trans position, and finally the preservation of the urea transport machinery following glutaraldehyde fixation. Urea 107-111 arginine vasopressin Homo sapiens 50-61 6807102-10 1982 This model can account for the selectivity of the vasopressin-stimulated urea transport, its inhibition by urea and thiourea analogues, the facilitated transport of urea, inhibition of tracer urea flux from either the cis or the trans position, and finally the preservation of the urea transport machinery following glutaraldehyde fixation. Urea 107-111 arginine vasopressin Homo sapiens 50-61 7392157-0 1980 Urea therapy for inappropriate antidiuretic hormone secretion from tuberculous meningitis. Urea 0-4 arginine vasopressin Homo sapiens 31-51 6257881-3 1981 Amrinone enhanced the effect of vasopressin and cyclic AMP on water and urea permeabilities, as well as the effect of vasopressin on sodium transport. Urea 72-76 arginine vasopressin Homo sapiens 32-43 6779639-1 1981 Membrane fluidity, urea permeability, and osmotic water permeability in toad urinary bladder are regularly enhanced by antidiuretic hormone (ADH). Urea 19-23 arginine vasopressin Homo sapiens 119-139 6779639-1 1981 Membrane fluidity, urea permeability, and osmotic water permeability in toad urinary bladder are regularly enhanced by antidiuretic hormone (ADH). Urea 19-23 arginine vasopressin Homo sapiens 141-144 6779639-3 1981 In this investigation ADH-stimulated changes in urea and osmotic water permeability and luminal membrane aggregates at room temperature (24.8 +/- 0.4 degrees C) and in the cold 10.6 +/- 0.2 degrees) were compared with corresponding changes in membrane fluidity, as assessed by n-butyramide permeability. Urea 48-52 arginine vasopressin Homo sapiens 22-25 6779639-6 1981 For ADH-stimulated transbladder urea movement, channels seem to be involved as well, and the change induced in membrane fluidity by ADH could be an underlying factor in their formation. Urea 32-36 arginine vasopressin Homo sapiens 4-7 6252784-1 1980 Vasopressin stimulates osmotic water flow and urea permeability in the toad urinary bladder via separate cAMP-responsive mechanisms. Urea 46-50 arginine vasopressin Homo sapiens 0-11 226713-5 1979 Low concentrations of vasopressin (1 mU/ml) activate urea transport with virtually no effect on water transport. Urea 53-57 arginine vasopressin Homo sapiens 22-33 226714-6 1979 When water transport was activated (0.1 mM 8 Br-cAMP) sigma urea approached 1.0 sigma urea also approached 1.0 at high vasopressin concentrations. Urea 86-90 arginine vasopressin Homo sapiens 119-130 226714-2 1979 Urea and water transport across the toad bladder can be separately activated by low concentrations of vasopressin or 8 Br-cAMP. Urea 0-4 arginine vasopressin Homo sapiens 102-113 226714-5 1979 When urea transport was activated (low concentration of vasopressin), sigma for urea and other solutes was low, (sigma urea, 0.08--0.39; sigma acetamide, 0.55; sigma ethylene glycol, 0.60). Urea 5-9 arginine vasopressin Homo sapiens 56-67 226714-5 1979 When urea transport was activated (low concentration of vasopressin), sigma for urea and other solutes was low, (sigma urea, 0.08--0.39; sigma acetamide, 0.55; sigma ethylene glycol, 0.60). Urea 80-84 arginine vasopressin Homo sapiens 56-67 226714-5 1979 When urea transport was activated (low concentration of vasopressin), sigma for urea and other solutes was low, (sigma urea, 0.08--0.39; sigma acetamide, 0.55; sigma ethylene glycol, 0.60). Urea 80-84 arginine vasopressin Homo sapiens 56-67 222966-1 1979 Vasopressin increases the permeability of receptor cells to water and, in tissues such as toad bladder, to solutes such as urea. Urea 123-127 arginine vasopressin Homo sapiens 0-11 495156-0 1979 Urea-induced inhibition of antidiuretic hormone (ADH) secretion. Urea 0-4 arginine vasopressin Homo sapiens 27-47 495156-0 1979 Urea-induced inhibition of antidiuretic hormone (ADH) secretion. Urea 0-4 arginine vasopressin Homo sapiens 49-52 222966-3 1979 In the present study, we have shown that inhibitors of oxidative metabolism (rotenone, dinitrophenol, and methylene blue) selectively inhibit either vasopressin-stimulated water flow or vasopressin-stimulated urea transport. Urea 209-213 arginine vasopressin Homo sapiens 186-197 222966-7 1979 We would conclude that water and urea transport, as examples of hormone-stimulated processes, have different links to cell metabolism, and that in addition to cyclic AMP, a non-nucleotide pathway may be involved in the action of vasopressin. Urea 33-37 arginine vasopressin Homo sapiens 229-240 197240-0 1977 Control of urea transport across toad urinary bladder by vasopressin: effect of periodate oxidation of the mucosal cell surface. Urea 11-15 arginine vasopressin Homo sapiens 57-68 409846-0 1977 Urea uptake and translocation in toad urinary bladder: the effect of antidiuretic hormone. Urea 0-4 arginine vasopressin Homo sapiens 69-89 409846-6 1977 The kinetics of the increase in urea permeability induced by antidiuretic hormone was also studied and it was similar (T1/2:4.3 min) to the kinetics of the increase in water permeability induced by the hormone (T1/2:5.6 min). Urea 32-36 arginine vasopressin Homo sapiens 61-81 188657-2 1977 A significant decrease of urine flow and a significant increase of osmolality, urea and cAMP was observed indicating that the distal nephron of the infant kidney is responsive to exogenous ADH and that its effect is mediated by cAMP. Urea 79-83 arginine vasopressin Homo sapiens 189-192 188657-4 1977 Furthermore the results raise the possibility that increasing concentrations of urea and solutes in the medulla and papilla of the infant kidney may have--in the presence of very low ADH secretion--an additional stimulating effect on cAMP formation. Urea 80-84 arginine vasopressin Homo sapiens 183-186 184113-2 1976 We have observed that three general anesthetic agents of clinical importance, the gases methoxyflurane and halothane and the ultrashortacting barbiturate methohexital, reversibly inhibit vasopressin-stimulated water flow, but do not depress permeability to urea, or the the lipophilic solute diphenylhydantoin. Urea 257-261 arginine vasopressin Homo sapiens 187-198 184113-6 1976 We conclude that the majority of water and urea transport takes place via separate pathways across the rate-limiting luminal membrane of the bladder cell, and that separate vasopressin-responsive cellular pools of cyclic AMP appear to control permeability to water and to urea. Urea 272-276 arginine vasopressin Homo sapiens 173-184 7705-1 1976 Vasopressin is known to increase the permeability of the toad bladder, an analogue of the mammalian collecting duct, to water and hydrophilic solutes such as urea. Urea 158-162 arginine vasopressin Homo sapiens 0-11 176362-2 1975 Urea and water transport across the toad bladder epithelial cell appears to take place through independent vasopressin-stimulated pathways. Urea 0-4 arginine vasopressin Homo sapiens 108-119 1126120-0 1975 Assessment of urine-concentrating ability in man: effect of fludrocortisone and urea in enhancing response to vasopressin. Urea 80-84 arginine vasopressin Homo sapiens 110-121 1126120-5 1975 Oral urea-loading also enhanced the urine-concentrating power of vasopressin but its effect was less marked than that of fludrocortisone. Urea 5-9 arginine vasopressin Homo sapiens 65-76 4201269-0 1973 Inhibition of vasopressin-stimulated urea transport across the toad bladder by thiourea. Urea 37-41 arginine vasopressin Homo sapiens 14-25 4201269-1 1973 The mammalian antidiuretic hormone, 8-arginine-vasopressin, was found to increase net mucosal-to-serosal urea flux across the isolated toad urinary bladder 13-fold. Urea 105-109 arginine vasopressin Homo sapiens 47-58 4201269-6 1973 When bladders were exposed to vasopressin on the serosa and subsequently fixed with 1% glutaraldehyde on the mucosa, they were found to retain 74% of their prefixation permeability to urea. Urea 184-188 arginine vasopressin Homo sapiens 30-41 5479370-0 1970 The effect of vasopressin on the reabsorption of sodium, potassium and urea by the renal tubules in man. Urea 71-75 arginine vasopressin Homo sapiens 14-25 4198196-0 1973 A saturable, vasopressin-sensitive carrier for urea and acetamide in the toad bladder epithelial cell. Urea 47-51 arginine vasopressin Homo sapiens 13-24 4198196-4 1973 These experiments indicate a competition between unlabeled and isotopic species for binding sites, and show the existence of a saturable, vasopressin-sensitive carrier for urea and acetamide in the epithelial cell membrane. Urea 172-176 arginine vasopressin Homo sapiens 138-149 4703229-2 1973 The present report presents evidence for a vasopressin-sensitive pathway for the movement of urea, other amides, and certain non-amides, which is independent of water flow. Urea 93-97 arginine vasopressin Homo sapiens 43-54 5952351-0 1966 [The influence of antidiuretic hormone on the urinary elimination of urea in man]. Urea 69-73 arginine vasopressin Homo sapiens 18-38 5780194-2 1969 Aldosterone enhanced the short-circuit current response, the osmotic water flow response, and the urea permeability response to vasopressin. Urea 98-102 arginine vasopressin Homo sapiens 128-139 13789147-0 1961 The influence of vasopressin on the permeability of the mammalian collecting duct to urea. Urea 85-89 arginine vasopressin Homo sapiens 17-28 13905690-5 1962 Urea had activation energies for diffusion of 4.1 and 3.9 kcal per mole in the absence and presence of vasopressin, respectively. Urea 0-4 arginine vasopressin Homo sapiens 103-114 14411877-0 1960 [Effect of vasopressin on urea excretion in diuresis produced by isotonic NaCl solution]. Urea 26-30 arginine vasopressin Homo sapiens 11-22 25925260-8 2015 Vasopressin allows the concentration of nitrogenous end products (urea, ammonia, etc.) Urea 66-70 arginine vasopressin Homo sapiens 0-11 25925260-12 2015 Altogether, glucagon, vasopressin, and urea contribute to set up the best compromise between efficient urea excretion and water economy. Urea 103-107 arginine vasopressin Homo sapiens 22-33 24920735-6 2014 Additional water retention may be mediated through vasopressin-induced medullary urea transport and hyaluronan but needs further study. Urea 81-85 arginine vasopressin Homo sapiens 51-62 5057132-1 1972 These experiments were intended to evaluate the antidiuretic hormone (ADH)-dependent reflection coefficients of urea, sucrose, and NaCl in cortical and outer medullary collecting tubules isolated from mammalian kidney. Urea 112-116 arginine vasopressin Homo sapiens 48-68 5057132-1 1972 These experiments were intended to evaluate the antidiuretic hormone (ADH)-dependent reflection coefficients of urea, sucrose, and NaCl in cortical and outer medullary collecting tubules isolated from mammalian kidney. Urea 112-116 arginine vasopressin Homo sapiens 70-73 5057132-3 1972 Similarly, both in cortical and outer medullary collecting tubules exposed to ADH, there was zero net osmotic volume flow when a portion of the NaCl in the bathing and/or perfusing solutions was replaced by either sucrose or urea, so long as the perfusing and bathing solutions were isosmolal. Urea 225-229 arginine vasopressin Homo sapiens 78-81 5057132-4 1972 Taken together, these observations suggest that the ADH-dependent reflection coefficients of NaCl, urea, and sucrose, in these tubules, were identical. Urea 99-103 arginine vasopressin Homo sapiens 52-55 5057132-7 1972 Since the limiting sites for urea penetration were the luminal interfaces of the tubules, these data are consistent with the view that ADH increases diffusional water flow across such interfaces. Urea 29-33 arginine vasopressin Homo sapiens 135-138