PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33360346-9 2021 Transcriptomics and bioinformatics results indicated that URE could regulate glutamatergic, cholinergic, serotonergic, and GABAergic systems, especially neuroactive ligand-receptor and cAMP signaling pathways, revealing that Htr1a encoding 5-HT1A receptor was a potential target of URE. Urea 58-61 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 225-230 33360346-9 2021 Transcriptomics and bioinformatics results indicated that URE could regulate glutamatergic, cholinergic, serotonergic, and GABAergic systems, especially neuroactive ligand-receptor and cAMP signaling pathways, revealing that Htr1a encoding 5-HT1A receptor was a potential target of URE. Urea 58-61 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 240-255 33360346-9 2021 Transcriptomics and bioinformatics results indicated that URE could regulate glutamatergic, cholinergic, serotonergic, and GABAergic systems, especially neuroactive ligand-receptor and cAMP signaling pathways, revealing that Htr1a encoding 5-HT1A receptor was a potential target of URE. Urea 282-285 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 225-230 33360346-9 2021 Transcriptomics and bioinformatics results indicated that URE could regulate glutamatergic, cholinergic, serotonergic, and GABAergic systems, especially neuroactive ligand-receptor and cAMP signaling pathways, revealing that Htr1a encoding 5-HT1A receptor was a potential target of URE. Urea 282-285 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 240-255 33360346-10 2021 The expression levels of downstream proteins of 5-HT1A signaling pathway 5-HT1A, CREB, BDNF, and PKA were increased in UCMS-induced mice after URE administration, and URE also displayed an agonistic effect against 5-HT1A receptor with an EC50 value of 17.42 mug/ml. Urea 143-146 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 48-54 33360346-10 2021 The expression levels of downstream proteins of 5-HT1A signaling pathway 5-HT1A, CREB, BDNF, and PKA were increased in UCMS-induced mice after URE administration, and URE also displayed an agonistic effect against 5-HT1A receptor with an EC50 value of 17.42 mug/ml. Urea 143-146 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 73-79 33360346-10 2021 The expression levels of downstream proteins of 5-HT1A signaling pathway 5-HT1A, CREB, BDNF, and PKA were increased in UCMS-induced mice after URE administration, and URE also displayed an agonistic effect against 5-HT1A receptor with an EC50 value of 17.42 mug/ml. Urea 167-170 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 48-54 33360346-10 2021 The expression levels of downstream proteins of 5-HT1A signaling pathway 5-HT1A, CREB, BDNF, and PKA were increased in UCMS-induced mice after URE administration, and URE also displayed an agonistic effect against 5-HT1A receptor with an EC50 value of 17.42 mug/ml. Urea 167-170 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 73-79 33360346-10 2021 The expression levels of downstream proteins of 5-HT1A signaling pathway 5-HT1A, CREB, BDNF, and PKA were increased in UCMS-induced mice after URE administration, and URE also displayed an agonistic effect against 5-HT1A receptor with an EC50 value of 17.42 mug/ml. Urea 167-170 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus 214-229