PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25774903-7 2015 Pretreatment with fingolimod-phosphate restored the changes in the claudin-5 and VCAM-1 protein/mRNA levels and TEER values in BMECs after exposure to MS sera. FTY 720P 18-38 vascular cell adhesion molecule 1 Homo sapiens 81-87 25774903-8 2015 CONCLUSIONS: Pretreatment with fingolimod-phosphate prevents BBB disruption caused by both RRMS and SPMS sera via the upregulation of claudin-5 and downregulation of VCAM-1 in BMECs, suggesting that fingolimod-phosphate is capable of directly modifying the BBB. FTY 720P 31-51 vascular cell adhesion molecule 1 Homo sapiens 166-172