PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27885332-3 2016 Our results showed that THSG dose-dependently increased the luciferase reporter activity of the klotho gene, reversed the decrease in mRNA and protein expression of klotho which was induced by angiotensin II in NRK-52E renal tubular epithelial cells, and increased klotho mRNA expression in the cerebral cortex, hippocampus, testis, and kidney medulla of spontaneously hypertensive rats. 2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside 24-28 angiotensinogen Rattus norvegicus 193-207 27885332-4 2016 THSG also reduced the number of senescent cells induced by angiotensin II and improved the antioxidant capacity and enhanced the bone strength in vivo. 2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside 0-4 angiotensinogen Rattus norvegicus 59-73