PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24144549-1 2014 A single central injection of angiotensin II (AngII) potently increases water intake; however, a growing body of research suggests that repeated, acute intracerebroventricular injections of AngII cause a reduction in the dipsogenic response to subsequent AngII. Water 72-77 angiotensinogen Homo sapiens 30-44 25388457-3 2015 Their mechanism of action involves the adjustment of balance between vasoconstrictive, hypertrophic and salt/water-retentive angiotensin II and vasodilatory and natriuretic bradykinin by the inhibition of angiotensin II biosynthesis and bradykinin degradation. Water 109-114 angiotensinogen Homo sapiens 125-139 25374825-2 2014 Mediators that play a significant role in regulating the transport of solutes and water include angiotensin II (AngII) and nitric oxide (NO). Water 82-87 angiotensinogen Homo sapiens 96-110 25374825-2 2014 Mediators that play a significant role in regulating the transport of solutes and water include angiotensin II (AngII) and nitric oxide (NO). Water 82-87 angiotensinogen Homo sapiens 112-117 27358027-3 2016 The haemodynamic and non-haemodynamic effects of Ang II, including its ability to regulate blood pressure, maintain water-electrolyte balance and promote vasoconstriction and cellular growth are well-documented to be mediated primarily by the AT1R. Water 116-121 angiotensinogen Homo sapiens 49-55 25858030-11 2015 Pharmacological blockade of the AT1 receptor with losartan prior to RNS abolished both the functional and the molecular responses, suggesting that intrarenal Ang II acting via the AT1 receptor is a major factor for NHE3-mediated sodium and water reabsorption induced by RNS. Water 240-245 angiotensinogen Homo sapiens 158-164 25477821-3 2014 In addition, inactivation of the LPBN induces overdrinking of water in response to a range of dipsogenic treatments primarily, but not exclusively, those associated with endogenous centrally acting angiotensin II. Water 62-67 angiotensinogen Homo sapiens 198-212 25024004-5 2014 Essentially, T-lymphocytes determine an increase in angiotensin ii production which raises sodium and water retention. Water 102-107 angiotensinogen Homo sapiens 52-66 24144549-1 2014 A single central injection of angiotensin II (AngII) potently increases water intake; however, a growing body of research suggests that repeated, acute intracerebroventricular injections of AngII cause a reduction in the dipsogenic response to subsequent AngII. Water 72-77 angiotensinogen Homo sapiens 46-51 24144549-1 2014 A single central injection of angiotensin II (AngII) potently increases water intake; however, a growing body of research suggests that repeated, acute intracerebroventricular injections of AngII cause a reduction in the dipsogenic response to subsequent AngII. Water 72-77 angiotensinogen Homo sapiens 190-195 24144549-1 2014 A single central injection of angiotensin II (AngII) potently increases water intake; however, a growing body of research suggests that repeated, acute intracerebroventricular injections of AngII cause a reduction in the dipsogenic response to subsequent AngII. Water 72-77 angiotensinogen Homo sapiens 190-195 24144549-6 2014 In support of this hypothesis, we found that repeated injections of AngII into the AV3V reduced water intake stimulated by a test injection of AngII given into this region. Water 96-101 angiotensinogen Homo sapiens 68-73 24144549-6 2014 In support of this hypothesis, we found that repeated injections of AngII into the AV3V reduced water intake stimulated by a test injection of AngII given into this region. Water 96-101 angiotensinogen Homo sapiens 143-148 24144549-7 2014 Moreover, repeated AngII injections in the AV3V reduced water intake after AngII was injected into the lateral ventricle. Water 56-61 angiotensinogen Homo sapiens 19-24 24015756-7 2013 By contrast, a series of positively selected amino acid residues identified in the ACE and AGT (two key members of the renin-angiotensin-aldosterone system, RAAS) proteins of cetaceans suggests that RAAS might have been adapted to maintain the water and salt balance in response to a hyperosmotic environment. Water 244-249 angiotensinogen Homo sapiens 91-94 24015756-7 2013 By contrast, a series of positively selected amino acid residues identified in the ACE and AGT (two key members of the renin-angiotensin-aldosterone system, RAAS) proteins of cetaceans suggests that RAAS might have been adapted to maintain the water and salt balance in response to a hyperosmotic environment. Water 244-249 angiotensinogen Homo sapiens 119-155 23797335-2 2013 In eels, Ang II acts on the area postrema, a sensory circumventricular organ (CVO) and elicits water intake but other sensory CVOs have not yet been found in the eel forebrain. Water 95-100 angiotensinogen Homo sapiens 9-15 23856493-3 2013 Intracerebroventricular infusion of Ang II at 1.0, 2.5, and 12.5 ng/min for 2 weeks caused dose-related increases in water intake, Ang II concentration in the cerebrospinal fluid, and blood pressure. Water 117-122 angiotensinogen Homo sapiens 36-42 23180052-3 2013 In the kidney, Ang II stimulates renal tubular water and salt reabsorption causing antinatriuresis and antidiuresis. Water 47-52 angiotensinogen Homo sapiens 15-21 23782508-6 2013 This updating seems to be mediated by the activation of angiotensin AT1 receptors in the dorsal hippocampus and local infusion of human angiotensin II (ANGII) was shown to mimic the water deprivation effects on memory reconsolidation. Water 182-187 angiotensinogen Homo sapiens 136-150 23782508-6 2013 This updating seems to be mediated by the activation of angiotensin AT1 receptors in the dorsal hippocampus and local infusion of human angiotensin II (ANGII) was shown to mimic the water deprivation effects on memory reconsolidation. Water 182-187 angiotensinogen Homo sapiens 152-157 22773836-7 2012 Studies using the H(2)O(2) biosensor HyPer2 reveal that angiotensin-II promotes increases in intracellular H(2)O(2). Water 18-23 angiotensinogen Homo sapiens 56-70 23176210-1 2013 The octapeptide angiotensin II (Ang II) plays a homeostatic role in the regulation of blood pressure and water and electrolyte balance, and also contributes to the progression of cardiovascular remodeling. Water 105-110 angiotensinogen Homo sapiens 16-30 23176210-1 2013 The octapeptide angiotensin II (Ang II) plays a homeostatic role in the regulation of blood pressure and water and electrolyte balance, and also contributes to the progression of cardiovascular remodeling. Water 105-110 angiotensinogen Homo sapiens 32-38 20346964-4 2010 The second set of experiments focused on the role of intracellular signaling pathways in water and saline intakes that are stimulated by angiotensin II (AngII). Water 89-94 angiotensinogen Homo sapiens 137-151 21029392-6 2011 These studies have identified plasma volume and urinary bladder stores as intrinsic stimuli that activate the formation of angiotensin II (AII) to stimulate water absorption behaviour. Water 157-162 angiotensinogen Homo sapiens 123-137 21029392-6 2011 These studies have identified plasma volume and urinary bladder stores as intrinsic stimuli that activate the formation of angiotensin II (AII) to stimulate water absorption behaviour. Water 157-162 angiotensinogen Homo sapiens 139-142 21412242-1 2011 Angiotensin (Ang) II, the main effector peptide of the renin-Ang system, increases arterial blood pressure through Ang II type 1A (AT(1a)) receptor-dependent arterial vasoconstriction and by decreasing renal salt and water excretion through extrarenal and intrarenal mechanisms. Water 217-222 angiotensinogen Homo sapiens 0-20 21528478-1 2011 INTRODUCTION: Angiotensin II (AngII), a peptide that regulates the water-electrolytic balance and blood pressure, is also known to influence cell proliferation. Water 67-72 angiotensinogen Homo sapiens 14-28 21528478-1 2011 INTRODUCTION: Angiotensin II (AngII), a peptide that regulates the water-electrolytic balance and blood pressure, is also known to influence cell proliferation. Water 67-72 angiotensinogen Homo sapiens 30-35 20486869-5 2010 With such combinations, while ARB inhibits the vasoconstricting action and aldosterone-secreting effects of angiotensin II, hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption and directly increases excretion of sodium and chloride in the distal tubule, and promotes water excretion. Water 300-305 angiotensinogen Homo sapiens 108-122 20346964-4 2010 The second set of experiments focused on the role of intracellular signaling pathways in water and saline intakes that are stimulated by angiotensin II (AngII). Water 89-94 angiotensinogen Homo sapiens 153-158 19948673-2 2009 In the kidney, angiotensin II exerts its effects to conserve salt and water through a combination of the hemodynamic control of renal blood flow and glomerular filtration rate and tubular epithelial cell sodium chloride and water transport mechanisms. Water 70-75 angiotensinogen Homo sapiens 15-29 21029011-1 2010 Accumulated studies reported that the natruretic dopamine (DA) and the anti-natruretic angiotensin II (Ang II) represent an important mechanism to regulate renal Na(+) and water excretion through intracellular secondary messengers to inhibit or activate renal proximal tubule (PT) Na(+), K(+)-ATPase (NKA). Water 172-177 angiotensinogen Homo sapiens 87-101 21029011-1 2010 Accumulated studies reported that the natruretic dopamine (DA) and the anti-natruretic angiotensin II (Ang II) represent an important mechanism to regulate renal Na(+) and water excretion through intracellular secondary messengers to inhibit or activate renal proximal tubule (PT) Na(+), K(+)-ATPase (NKA). Water 172-177 angiotensinogen Homo sapiens 103-109 19948673-2 2009 In the kidney, angiotensin II exerts its effects to conserve salt and water through a combination of the hemodynamic control of renal blood flow and glomerular filtration rate and tubular epithelial cell sodium chloride and water transport mechanisms. Water 224-229 angiotensinogen Homo sapiens 15-29 19118280-0 2009 Suppression of peroxisome proliferator-activated receptor-gamma activity by angiotensin II in vascular smooth muscle involves Bcr kinase: the fire that drowns the water. Water 163-168 angiotensinogen Homo sapiens 76-90 19805637-7 2009 Our results demonstrate that both Nox2 and Nox4 are required for the full vasopressor effects of brain Ang-II but that only Nox2 is coupled to the Ang-II-induced water intake response. Water 162-167 angiotensinogen Homo sapiens 147-153 19348229-1 2009 The octapeptide angiotensin II (AngII) plays a homeostatic role in the regulation of blood pressure and water and electrolyte balance, and contributes to the progression of cardiovascular remodeling. Water 104-109 angiotensinogen Homo sapiens 16-30 19348229-1 2009 The octapeptide angiotensin II (AngII) plays a homeostatic role in the regulation of blood pressure and water and electrolyte balance, and contributes to the progression of cardiovascular remodeling. Water 104-109 angiotensinogen Homo sapiens 32-37 17596524-0 2007 The thiazide-sensitive NaCl cotransporter: a new target for acute regulation of salt and water transport by angiotensin II. Water 89-94 angiotensinogen Homo sapiens 108-122 19728302-10 2009 CD spectra showed that although both AII and TOAC1-AII presented flexible conformations in water, TOAC3-AII displayed conformational restriction because of the TOAC-imposed bend (Schreier et al., Biopolymers 2004, 74, 389). Water 91-96 angiotensinogen Homo sapiens 37-40 19728302-10 2009 CD spectra showed that although both AII and TOAC1-AII presented flexible conformations in water, TOAC3-AII displayed conformational restriction because of the TOAC-imposed bend (Schreier et al., Biopolymers 2004, 74, 389). Water 91-96 angiotensinogen Homo sapiens 51-54 19728302-10 2009 CD spectra showed that although both AII and TOAC1-AII presented flexible conformations in water, TOAC3-AII displayed conformational restriction because of the TOAC-imposed bend (Schreier et al., Biopolymers 2004, 74, 389). Water 91-96 angiotensinogen Homo sapiens 51-54 20641953-3 2004 Angiotensin II also stimulates the production of aldosterone from the adrenal glands, which promotes retention of sodium and water. Water 125-130 angiotensinogen Homo sapiens 0-14 18543871-0 2008 Solvent interactions with [Val(5)]angiotensin II in ethanol-water. Water 60-65 angiotensinogen Homo sapiens 34-48 20641324-3 2004 Angiotensin II also stimulates the production of aldosterone from the adrenal glands that promotes sodium and water retention. Water 110-115 angiotensinogen Homo sapiens 0-14 18186457-7 2008 In addition, linearity in the range 9.5-95 nM was obtained for the peptide angiotensin-II in deionized water with a correlation of estimation of 0.992 using an internal standard. Water 103-108 angiotensinogen Homo sapiens 75-89 18687780-1 2008 Circulating angiotensin II (ANGII) elicits water intake and activates the hypothalamic-pituitary-adrenal (HPA) axis by stimulating angiotensin type 1 receptors (AT1Rs) within circumventricular organs. Water 43-48 angiotensinogen Homo sapiens 12-26 18687780-1 2008 Circulating angiotensin II (ANGII) elicits water intake and activates the hypothalamic-pituitary-adrenal (HPA) axis by stimulating angiotensin type 1 receptors (AT1Rs) within circumventricular organs. Water 43-48 angiotensinogen Homo sapiens 28-33 18360029-0 2008 A water-soluble fullerene vesicle alleviates angiotensin II-induced oxidative stress in human umbilical venous endothelial cells. Water 2-7 angiotensinogen Homo sapiens 45-59 18360029-9 2008 These observations show that the PhK water-soluble fullerene vesicle is promising as a compound controlling not only exogenous ROS, but also endogenous AII-mediated pathophysiological conditions. Water 37-42 angiotensinogen Homo sapiens 152-155 17329311-3 2007 Thus, it is not surprising that angiotensin II, which is synthesized in response to hypovolaemia, acts centrally to increase both water and NaCl intake. Water 130-135 angiotensinogen Homo sapiens 32-46 17631057-0 2007 Inhibitory effects of Zoagumhwan water extract and berberine on angiotensin II-induced monocyte chemoattractant protein (MCP)-1 expression and monocyte adhesion to endothelial cells. Water 33-38 angiotensinogen Homo sapiens 64-78 17556883-1 2007 PURPOSE OF REVIEW: Angiotensin II regulates vasoconstriction, homeostasis of salt and water, and cardiovascular hypertrophy and remodeling. Water 86-91 angiotensinogen Homo sapiens 19-33 16650887-9 2006 The results described in this paper provide evidence that calcium channels play important roles in the ANGII-induced behavioral water intake. Water 128-133 angiotensinogen Homo sapiens 103-108 16256193-1 2006 We used the in vitro dually perfused human placental lobule to test the hypothesis that known vasoconstrictors of the fetal placental circulation, angiotensin II and the thromboxane mimetic U46619 could induce fetomaternal water transfer. Water 223-228 angiotensinogen Homo sapiens 147-161 16650887-2 2006 We have show previously the central involvement of angiotensin II (ANGII) in water intake. Water 77-82 angiotensinogen Homo sapiens 51-65 16650887-2 2006 We have show previously the central involvement of angiotensin II (ANGII) in water intake. Water 77-82 angiotensinogen Homo sapiens 67-72 15993982-4 2005 Under a drying condition where the water inflow from outside the body was eliminated, Ang II suppressed body weight loss, but Ang III did not. Water 35-40 angiotensinogen Homo sapiens 86-92 16601568-2 2006 RESULTS: AT1-receptor activation by angiotensin II is not only involved in the regulation of blood pressure, water and sodium homeostasis, and control of other neurohumoral systems, but also leads to excessive production of reactive oxygen species and to hypertrophy, proliferation, migration, and apoptosis of vascular cells. Water 109-114 angiotensinogen Homo sapiens 36-50 16142301-1 2005 Angiotensin II, a potent vasoconstrictor, also participates in the regulation of renal sodium and water excretion, not only via a myriad of effects on renal hemodynamics, glomerular filtration rate, and regulation of aldosterone secretion, but also via direct effects on renal tubule transport. Water 98-103 angiotensinogen Homo sapiens 0-14 16197516-0 2005 Memory strengthening by a real-life episode during reconsolidation: an outcome of water deprivation via brain angiotensin II. Water 82-87 angiotensinogen Homo sapiens 110-124 16197516-8 2005 We show that memory reconsolidation, induced by training context re-exposure, is facilitated by a concurrent episode of water deprivation, which induces a raise in endogenous brain angiotensin II. Water 120-125 angiotensinogen Homo sapiens 181-195 15976682-4 2005 Most, if not all, of the peripheral and central actions of angiotensin II, including vasoconstriction, renal salt and water retention, facilitation of sympathetic transmission, modification of vascular and cardiac structure, oxydative stress stimulation and proinflammatory action were all thought to be mediated by the angiotensin type 1 receptor, AT1. Water 118-123 angiotensinogen Homo sapiens 59-73 16080698-0 2005 Condensation reaction between angiotensin II and dicarboxylic acid in water at high temperature without any catalytic agent additive. Water 70-75 angiotensinogen Homo sapiens 30-44 16080698-1 2005 The condensation reaction of angiotensin II and tartaric acid in water at 100-140 degrees C proceeded without any added catalytic agent. Water 65-70 angiotensinogen Homo sapiens 29-43 15740899-3 2005 cIEF-MS employing 1% Pharmalyte 3-10 and a sheath liquid containing water/methanol/acetic acid (50/49/1) resolved angiotensin I and II (5 microM each, DeltapI=0.2) at an Rs value of 2.29. Water 68-73 angiotensinogen Homo sapiens 114-134 16041122-0 2005 Angiotensin III as well as angiotensin II regulates water flow through aquaporins in a clam worm. Water 52-57 angiotensinogen Homo sapiens 27-41 16041122-7 2005 Since tetrachloroaurate (III) is a representative blocker of aquaporins, these results indicate that angiotensin III as well as angiotensin II regulates water flow through aquaporins in clam worms. Water 153-158 angiotensinogen Homo sapiens 101-115 15614025-1 2004 OBJECTIVE: Angiotensin II and aldosterone, generated by the angiotensin-converting enzyme (ACE) and aldosterone synthase (CYP11B2), respectively, not only regulate sodium and water homeostasis, but also influence vascular remodeling in response to high blood pressure. Water 175-180 angiotensinogen Homo sapiens 11-25 15090867-9 2004 When inappropriately stimulated, high intrarenal angiotensin II levels contribute to excessive salt and water retention, the development of hypertension, and long-term proliferative effects leading to renal injury. Water 104-109 angiotensinogen Homo sapiens 49-63 15500134-2 2004 All classic physiological effects of AII, such as vasoconstriction, aldosterone and vasopressin release, sodium and water retention and sympathetic facilitation, are mediated by the AT1 receptor. Water 116-121 angiotensinogen Homo sapiens 37-40 15099911-0 2004 Interaction between supraoptic nucleus and septal area in the control of water, sodium intake and arterial blood pressure induced by injection of angiotensin II. Water 73-78 angiotensinogen Homo sapiens 146-160 14988040-1 2004 Our recent results showed that angiotensin II or III (AII, AIII) microinjected into the zona incerta (ZI) significantly increased water intake. Water 130-135 angiotensinogen Homo sapiens 31-52 12746271-2 2003 Indeed, some of the properties of the physiologically active component of the RAS, angiotensin II, include vasoconstriction, regulation of renal sodium and water absorption, and increasing thirst. Water 156-161 angiotensinogen Homo sapiens 83-97 12759348-2 2003 Dopamine and angiotensin II have antagonistic effects on renal Na+ and water excretion, which involves regulation of the Na+,K+-ATPase activity. Water 71-76 angiotensinogen Homo sapiens 13-27 12752436-2 2003 Conformational analysis of angiotensin I (AI) and II (AII) peptides has been performed through 2D 1H-NMR spectroscopy in dimethylsulfoxide and 2,2,2-trifluoroethanol/H2O. Water 166-169 angiotensinogen Homo sapiens 27-52 12676175-6 2003 Centrally administered AT(1) receptor antagonists or angiotensinogen antisense oligonucleotides inhibit sympathetic activity and reduce arterial blood pressure in certain physiological or pathophysiological conditions, as well as disrupting water drinking and sodium appetite, vasopressin secretion, sodium excretion, renin release and thermoregulation. Water 241-246 angiotensinogen Homo sapiens 53-68 12763668-1 2003 Angiotensin II is shown by nuclear magnetic resonance (NMR) to form a complex in water at pH 4.0 with cerium(III), the ideal paramagnetic probe for Ca(2+). Water 81-86 angiotensinogen Homo sapiens 0-14 12563518-1 2003 Angiotensin II and atrial natriuretic peptide (ANP) play important and opposite roles in the control of water and salt intake, with angiotensin II promoting the intake of both and ANP inhibiting the intake of both. Water 104-109 angiotensinogen Homo sapiens 0-14 12642017-5 2003 In the cortical collecting duct, AT(1) receptors stimulate transport through apical sodium channels, and in the inner medulla, urea transport is enhanced by Ang II, contributing to increased sodium and water reabsorption. Water 202-207 angiotensinogen Homo sapiens 157-163 11785064-9 2002 Also, activation of the renin-angiotensin system increases the levels of angiotensin II in the plasma, leading to generalized vasoconstriction, or locally in the kidneys, leading to salt and water retention. Water 191-196 angiotensinogen Homo sapiens 73-87 12573139-1 2002 Angiotensin II has been shown to participate in both physiological processes, such as sodium and water homeostasis and vascular contraction, and pathophysiological processes, including atherosclerosis and hypertension. Water 97-102 angiotensinogen Homo sapiens 0-14 11983705-5 2002 Here we use modification of reporter cysteines to measure water accessibility at specific residues in TM2 of the type 1 receptor for the octapeptide hormone angiotensin II. Water 58-63 angiotensinogen Homo sapiens 157-171 12069945-0 2002 Angiotensin II attenuates the natriuresis of water immersion in humans. Water 45-50 angiotensinogen Homo sapiens 0-14 11799146-1 2002 Angiotensin II (Ang II) regulates water and sodium transport in renal tubules and gastrointestinal tract. Water 34-39 angiotensinogen Homo sapiens 0-14 11799146-1 2002 Angiotensin II (Ang II) regulates water and sodium transport in renal tubules and gastrointestinal tract. Water 34-39 angiotensinogen Homo sapiens 16-22 12036388-1 2002 The octapeptide angiotensin II (Ang II), the potent effector molecule of the renin-angiotensin-aldosterone system (RAAS), is involved in the control of blood pressure, cardiac and vascular function as well as sodium and water homeostasis. Water 220-225 angiotensinogen Homo sapiens 16-30 12036388-1 2002 The octapeptide angiotensin II (Ang II), the potent effector molecule of the renin-angiotensin-aldosterone system (RAAS), is involved in the control of blood pressure, cardiac and vascular function as well as sodium and water homeostasis. Water 220-225 angiotensinogen Homo sapiens 32-38 11231042-0 2001 Atypical angiotensin receptors may mediate water intake induced by central injections of angiotensin II and of serotonin in pigeons. Water 43-48 angiotensinogen Homo sapiens 89-103 11828179-2 2001 In this regard, angiotensin II maintains and regulates salt and water balance, is critically involved in cardiovascular function, and governs thirst. Water 64-69 angiotensinogen Homo sapiens 16-30 11231042-9 2001 At the doses presently used both 5-HT and ANGII treatments evoked comparable water intake amounts with similar behavioral profiles. Water 77-82 angiotensinogen Homo sapiens 42-47 11231042-10 2001 While pretreatment with SAR dose-dependently reduced the water intake evoked by both 5-HT and ANGII, neither losartan nor PD 123,319 pretreatment affected the drinking induced by these treatments. Water 57-62 angiotensinogen Homo sapiens 94-99 10904236-5 2000 The renin-angiotensin system (RAS), through the important effector peptide, angiotensin II (Ang II), has potent effects on blood pressure, salt and water homeostasis, and target-organ damage. Water 148-153 angiotensinogen Homo sapiens 76-90 11403985-0 2001 Role of the alpha(1)- and alpha(2)-adrenoceptors of the paraventricular nucleus on the water and salt intake, renal excretion, and arterial pressure induced by angiotensin II injection into the medial septal area. Water 87-92 angiotensinogen Homo sapiens 160-174 11403985-2 2001 ANG II injection into the MSA induced water and sodium intake, diuresis, natriuresis, and pressor responses. Water 38-43 angiotensinogen Homo sapiens 0-6 11403985-4 2001 Previous injection of a nonselective alpha-adrenergic antagonist, regitin, into the PVN blocked the urinary excretion, and reduced the water and sodium intake, sodium intake, and pressor responses induced by ANG II injected into the MSA. Water 135-140 angiotensinogen Homo sapiens 208-214 11259763-1 2001 Angiotensin II (ANG-II) and atrial natriuretic peptide (ANP) have opposing actions on water and salt intake and excretion. Water 86-91 angiotensinogen Homo sapiens 0-14 11259763-1 2001 Angiotensin II (ANG-II) and atrial natriuretic peptide (ANP) have opposing actions on water and salt intake and excretion. Water 86-91 angiotensinogen Homo sapiens 16-22 11259763-5 2001 Injection of ANG-II (12.5 ng) into the anteroventral region of the third ventricle (AV3V) at the effective dose to increase water intake increased plasma ANP concentrations (P<0.01) within 5 min. Water 124-129 angiotensinogen Homo sapiens 13-19 11259763-6 2001 As described before, previous injection of phenylephrine (an alpha(1)-adrenergic agonist) or clonidine (an alpha(2)-adrenergic agonist) into the AV3V region significantly reduced ANG-II-induced water intake. Water 194-199 angiotensinogen Homo sapiens 179-185 11259763-8 2001 These results suggest that the inhibitory effect of both alpha-adrenergic agonists on ANG-II-induced water intake can be explained, at least in part, by the increase in ANP content and presumed release from these neural structures. Water 101-106 angiotensinogen Homo sapiens 86-92 11441521-1 2001 Angiotensin II plays an important role in blood pressure control and in water and salt homeosthasis. Water 72-77 angiotensinogen Homo sapiens 0-14 10718175-2 2000 Angiotensin II (A II) is well-known in the systemic control of water and electrolyte homeostasis and haemodynamics, but recent evidence points to an additional local renin-angiotensin system (RAS) with possible long-term trophic effects including carcinogenesis. Water 63-68 angiotensinogen Homo sapiens 0-14 10718175-2 2000 Angiotensin II (A II) is well-known in the systemic control of water and electrolyte homeostasis and haemodynamics, but recent evidence points to an additional local renin-angiotensin system (RAS) with possible long-term trophic effects including carcinogenesis. Water 63-68 angiotensinogen Homo sapiens 16-20 10691781-7 2000 In the gastrointestinal tract, physiological quantities of ANG II stimulate the AT2 receptor releasing NO and cGMP leading to increased sodium and water absorption. Water 147-152 angiotensinogen Homo sapiens 59-65 10766956-1 2000 We used 206.5-nm excited resonance Raman measurements to examine the angiotensin II (AII) secondary structure in H(2)O in the presence of dodecylphosphocholine (DPC) micelles, sodium dodecylsulfate (SDS) monomers and micelles, and in a 70% acetonitrile (ACN-d)-30% water solution. Water 113-118 angiotensinogen Homo sapiens 69-83 10766956-1 2000 We used 206.5-nm excited resonance Raman measurements to examine the angiotensin II (AII) secondary structure in H(2)O in the presence of dodecylphosphocholine (DPC) micelles, sodium dodecylsulfate (SDS) monomers and micelles, and in a 70% acetonitrile (ACN-d)-30% water solution. Water 113-118 angiotensinogen Homo sapiens 85-88 10904236-5 2000 The renin-angiotensin system (RAS), through the important effector peptide, angiotensin II (Ang II), has potent effects on blood pressure, salt and water homeostasis, and target-organ damage. Water 148-153 angiotensinogen Homo sapiens 92-98 10682705-1 2000 Increasing evidence suggests that Angiotensin II, classically known from its many effects regulating salt and water homeostasis, is also involved in brain development and cognitive functions through activation of AT1 Angiotensin II receptors. Water 110-115 angiotensinogen Homo sapiens 34-48 10682705-1 2000 Increasing evidence suggests that Angiotensin II, classically known from its many effects regulating salt and water homeostasis, is also involved in brain development and cognitive functions through activation of AT1 Angiotensin II receptors. Water 110-115 angiotensinogen Homo sapiens 217-231 10619595-2 1999 Because Ang II affects blood pressure control, sodium and water homeostasis, and cardiovascular function and structure, a great deal of research effort has been directed toward blocking the RAS. Water 58-63 angiotensinogen Homo sapiens 8-14 10619573-4 1999 Angiotensin II also alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Water 44-49 angiotensinogen Homo sapiens 0-14 9855025-2 1998 Because angiotensin II affects blood pressure control, sodium and water homeostasis, and cardiovascular function and structure, a great deal of research effort has been directed toward blocking the renin-angiotensin system. Water 66-71 angiotensinogen Homo sapiens 8-22 10437737-2 1999 Angiotensin II is the principal effector hormone in the RAS, causing vasoconstriction and increased sodium and water retention, leading to increased blood pressure. Water 111-116 angiotensinogen Homo sapiens 0-14 10750587-1 1999 Angiotensin II modulates beat-to-beat cardiac performance as a potent vasocontrictor, inotrope, and regulator of water and electrolyte balance. Water 113-118 angiotensinogen Homo sapiens 0-14 10372513-7 1999 Phenylephrine increased the dipsogenic responses produced by ANG II, whereas previous treatment with clonidine injected into the LH reduced the water intake induced by ANG II administration into the SFO. Water 144-149 angiotensinogen Homo sapiens 168-174 9809195-12 1998 Higher levels of AngII in the bloodstream activate additional neurons in the outer parts of the SFO that connect to the supraoptic, paraventricular and median preoptic nuclei and these probably mediate water drinking and vasopressin secretion induced by blood-borne AngII. Water 202-207 angiotensinogen Homo sapiens 17-22 10361429-3 1999 Angiotensin II in the brain increases water and sodium intake, raises blood pressure, attenuates baro-reflex function, and increases vasopressin secretion. Water 38-43 angiotensinogen Homo sapiens 0-14 10372513-0 1999 Effects of the alpha antagonists and agonists injected into the lateral hypothalamus on the water and sodium intake induced by angiotensin II injection into the subfornical organ. Water 92-97 angiotensinogen Homo sapiens 127-141 10372513-1 1999 The subfornical organ (SFO) and the lateral hypothalamus (LH) have been shown to be important for the central action of angiotensin II (ANG II) on water and salt regulation. Water 147-152 angiotensinogen Homo sapiens 120-134 10372513-1 1999 The subfornical organ (SFO) and the lateral hypothalamus (LH) have been shown to be important for the central action of angiotensin II (ANG II) on water and salt regulation. Water 147-152 angiotensinogen Homo sapiens 136-142 10372513-3 1999 The present experiments were conducted to investigate the role of the alpha-adrenergic antagonists and agonists injected into the LH on the water and salt intake elicited by injections of ANG II into the SFO. Water 140-145 angiotensinogen Homo sapiens 188-194 10372513-6 1999 Previous treatment with prazosin and propranolol reduced the water intake induced by ANG II. Water 61-66 angiotensinogen Homo sapiens 85-91 9679185-2 1998 The hypothesis was tested that in hydrated humans the release of arginine vasopressin and angiotensin II is suppressed by water immersion (WI) and that this is a mechanism of the immersion-induced diuresis and natriuresis. Water 122-127 angiotensinogen Homo sapiens 90-104 9692673-2 1998 Neuronal AT1 receptors mediate the stimulatory actions of Ang II on blood pressure, water and salt intake, and secretion of vasopressin. Water 84-89 angiotensinogen Homo sapiens 58-64 9326738-0 1997 Effect of rilmenidine injection into the paraventricular nucleus of the hypothalamus on the water intake induced by application of angiotensin II to the subfornical organ. Water 92-97 angiotensinogen Homo sapiens 131-145 9548645-4 1998 The water absorption response could be induced by intraperitoneal and intracerebroventricular injection of angiotensin II, demonstrating that components of the renin-angiotensin system on both sides of the blood-brain barrier have a dipsogenic function in amphibians. Water 4-9 angiotensinogen Homo sapiens 107-121 9251761-2 1997 These neurons act to inhibit water and salt intake by blocking the action of angiotensin II. Water 29-34 angiotensinogen Homo sapiens 77-91 9248673-7 1997 In addition, an interaction between TGF and angiotensin II (AngII) seems to be essential to maintaining GFR despite large variations in daily intake of salt and water. Water 161-166 angiotensinogen Homo sapiens 44-58 8738251-0 1996 Role of the alpha 1-, and alpha 2- and beta-adrenoceptors of the median preoptic area on the water intake, renal excretion, and arterial pressure induced by ANG II. Water 93-98 angiotensinogen Homo sapiens 157-163 9296068-12 1997 Angiotensiongen is the substrate of renin, and the renin-angiotensinogen reaction is the first and limiting step in the pathway that leads to production of angiotensin II, a peptide with important effects on blood pressure control and the metabolism of water and sodium. Water 253-258 angiotensinogen Homo sapiens 57-72 9296068-12 1997 Angiotensiongen is the substrate of renin, and the renin-angiotensinogen reaction is the first and limiting step in the pathway that leads to production of angiotensin II, a peptide with important effects on blood pressure control and the metabolism of water and sodium. Water 253-258 angiotensinogen Homo sapiens 156-170 8987761-1 1997 The activation of neurons in the subfornical organ (SFO) by angiotensin II (AngII) is well established and is widely regarded as the basis for the AngII-induced increase in water intake. Water 173-178 angiotensinogen Homo sapiens 147-152 8987761-7 1997 These electrophysiological results suggest an important role for NO in SFO-mediated responses and offer a plausible explanation for the in vivo-observed opposite effects of AngII and NO on water intake. Water 189-194 angiotensinogen Homo sapiens 173-178 9022280-2 1996 Angiotensin II, the end product of the reaction, is an extremely potent vasoconstrictor and a major determinant of salt and water homeostasis. Water 124-129 angiotensinogen Homo sapiens 0-14 21143283-2 1996 The effects of angiotensin II (AngII) on water and electrolyte transport are biphasic and dose-dependent, such that low concentrations (10(-12) to 10(-9) mol/L) stimulate reabsorption and high concentrations (10(-7) to 10(-6) mol/L) inhibit reabsorption. Water 41-46 angiotensinogen Homo sapiens 15-29 21143283-2 1996 The effects of angiotensin II (AngII) on water and electrolyte transport are biphasic and dose-dependent, such that low concentrations (10(-12) to 10(-9) mol/L) stimulate reabsorption and high concentrations (10(-7) to 10(-6) mol/L) inhibit reabsorption. Water 41-46 angiotensinogen Homo sapiens 31-36 8987761-1 1997 The activation of neurons in the subfornical organ (SFO) by angiotensin II (AngII) is well established and is widely regarded as the basis for the AngII-induced increase in water intake. Water 173-178 angiotensinogen Homo sapiens 60-74 8987761-1 1997 The activation of neurons in the subfornical organ (SFO) by angiotensin II (AngII) is well established and is widely regarded as the basis for the AngII-induced increase in water intake. Water 173-178 angiotensinogen Homo sapiens 76-81 8738251-2 1996 Prazosin (an alpha 1-adrenergic receptor antagonist) and yohimbine (an alpha 2-adrenergic receptor antagonist) antagonized the water ingestion, Na+, K+, and urine excretion induced by ANG II. Water 127-132 angiotensinogen Homo sapiens 184-190 8993849-2 1996 The effects of angiotensin II (AngII) on water and electrolyte transport are biphasic and dose-dependent, such that low concentrations (10(-12) to 10(-9) mol/L) stimulate reabsorption and high concentrations (10(-7) to 10(-6) mol/L) inhibit reabsorption. Water 41-46 angiotensinogen Homo sapiens 15-29 8993849-2 1996 The effects of angiotensin II (AngII) on water and electrolyte transport are biphasic and dose-dependent, such that low concentrations (10(-12) to 10(-9) mol/L) stimulate reabsorption and high concentrations (10(-7) to 10(-6) mol/L) inhibit reabsorption. Water 41-46 angiotensinogen Homo sapiens 31-36 8105791-8 1993 Angiotensin II releases vasopressin; this could explain water intoxication, which occurs later in the syndrome. Water 56-61 angiotensinogen Homo sapiens 0-14 8617893-8 1996 Previous work from this laboratory reported that osmotic water permeability in the skin of the toad Bufo arenarum was increased by angiotensin II, the effect being blocked by the peptide antagonist Leu8 angiotensin II. Water 57-62 angiotensinogen Homo sapiens 131-145 8617893-8 1996 Previous work from this laboratory reported that osmotic water permeability in the skin of the toad Bufo arenarum was increased by angiotensin II, the effect being blocked by the peptide antagonist Leu8 angiotensin II. Water 57-62 angiotensinogen Homo sapiens 203-217 7611515-2 1995 ANG II (10 ng) microinjected into the OCPLT significantly increased water consumption but did not induce intake of a hypertonic (3%) NaCl solution. Water 68-73 angiotensinogen Homo sapiens 0-6 7611515-6 1995 These findings suggest that water intake produced by microinjection of ANG II into the OCPLT is mediated by AT1 receptors uniquely and that, in contrast to other regions of the brain, these receptors do not induce salt intake when stimulated by ANG II. Water 28-33 angiotensinogen Homo sapiens 71-77 7624014-1 1995 Angiotensin II (ANGII) is known to activate neurons in the subfornical organ (SFO) of mammals and birds and this activation is regarded as the basis for the ANGII induced increase in water intake. Water 183-188 angiotensinogen Homo sapiens 0-14 7624014-1 1995 Angiotensin II (ANGII) is known to activate neurons in the subfornical organ (SFO) of mammals and birds and this activation is regarded as the basis for the ANGII induced increase in water intake. Water 183-188 angiotensinogen Homo sapiens 16-21 7624014-1 1995 Angiotensin II (ANGII) is known to activate neurons in the subfornical organ (SFO) of mammals and birds and this activation is regarded as the basis for the ANGII induced increase in water intake. Water 183-188 angiotensinogen Homo sapiens 157-162 7624014-3 1995 These data, in combination with the histochemical detection of NO synthase in the duck SFO, demonstrate the involvement of NO in SFO mediated responses and might represent the cellular basis for the observed opposite effects of ANGII and NO on water intake. Water 244-249 angiotensinogen Homo sapiens 228-233 8590217-1 1995 The peptide hormones angiotensin II and vasopressin play a major role in water and electrolyte homeostasis. Water 73-78 angiotensinogen Homo sapiens 21-35 7634256-3 1994 Angiotensin II and renin also regulate the input of water and salt through an unequivocal dipsogenic effect. Water 52-57 angiotensinogen Homo sapiens 0-14 8203370-3 1994 Mechanisms by which angiotensin II, hypokalemia, and proteinuria can affect salt and water balances, and the role of angiotensin II as a cause of heavy proteinuria are discussed. Water 85-90 angiotensinogen Homo sapiens 20-34 1516268-4 1992 The effects of AII on water and electrolyte transport are biphasic and dose-dependent, such that low concentrations (10(-12)-10(-9) mol/L) stimulate reabsorption whereas high concentrations (10(-7)-10(-6) mol/L) inhibit reabsorption. Water 22-27 angiotensinogen Homo sapiens 15-18 8396270-9 1993 As well, change in osmolality and/or angiotensin II level, associated with alterations in water and electrolyte balance, act as stimuli to ventilation and interact with chemical control. Water 90-95 angiotensinogen Homo sapiens 37-51 1336524-8 1992 Angiotensin II alone also increased fractional reabsorption of sodium delivered to the distal nephron, as evaluated by both the CLi method and by estimation of solute-free water clearance. Water 172-177 angiotensinogen Homo sapiens 0-14 1614946-0 1992 Response to angiotensin II after selective lesioning of brain regions believed to be involved in water intake regulation. Water 97-102 angiotensinogen Homo sapiens 12-26 1614946-9 1992 Feed intake was suppressed and water intake increased by ANGII injection. Water 31-36 angiotensinogen Homo sapiens 57-62 1614946-10 1992 The present study indicates that the SFO, but not the OVLT, plays a role in ANGII-induced water intake in broiler chicks. Water 90-95 angiotensinogen Homo sapiens 76-81 1516268-2 1992 Independent of its effects on renal haemodynamics and glomerular filtration, angiotensin II (AII) has direct actions on the proximal tubule involving transepithelial Na+, H+, HCO3-, and water reabsorption, ammoniagenesis, gluconeogenesis and renal growth. Water 186-191 angiotensinogen Homo sapiens 77-91 1516268-2 1992 Independent of its effects on renal haemodynamics and glomerular filtration, angiotensin II (AII) has direct actions on the proximal tubule involving transepithelial Na+, H+, HCO3-, and water reabsorption, ammoniagenesis, gluconeogenesis and renal growth. Water 186-191 angiotensinogen Homo sapiens 93-96 1654278-1 1991 The interaction of Zn2+ with angiotensin I, a decapeptide containing two histidyl residues, has been studied by 1H-NMR spectroscopy in both water and dimethylsulfoxide. Water 140-145 angiotensinogen Homo sapiens 29-42 1652115-6 1991 In conclusion, reduced water and sodium excretion after frusemide in the nephrotic syndrome is accompanied by a diminished reduction of blood volume, a delayed decrease in atrial natriuretic peptide, and a blunted increase in angiotensin II and aldosterone compared with healthy subjects. Water 23-28 angiotensinogen Homo sapiens 226-240 34575135-5 2021 In addition, ET-1 is involved in the complex regulation of BP through synergistic interactions with angiotensin II, regulates the production of catecholamines and sympathetic activity, affects renal hemodynamics and water-salt balance, and regulates baroreceptor activity and myocardial contractility. Water 216-221 angiotensinogen Homo sapiens 100-114 2185149-1 1990 Angiotensin II has recently been shown to exert potent control over sodium and water absorption in the proximal convoluted tubule. Water 79-84 angiotensinogen Homo sapiens 0-14 2188439-2 1990 This class of agents effectively inhibits the conversion of angiotensin I to the active vasoconstrictor angiotensin II, a hormone that also promotes, via aldosterone stimulation, increased sodium and water retention. Water 200-205 angiotensinogen Homo sapiens 60-73 2188439-2 1990 This class of agents effectively inhibits the conversion of angiotensin I to the active vasoconstrictor angiotensin II, a hormone that also promotes, via aldosterone stimulation, increased sodium and water retention. Water 200-205 angiotensinogen Homo sapiens 104-118 2532457-4 1989 In many physiologic situations including postural changes, volume expansion, water immersion, high altitude, and lower body negative pressure, the plasma levels of ANP and angiotensin II change inversely. Water 77-82 angiotensinogen Homo sapiens 172-186 2626449-1 1989 The subfornical organ plays a role in a number of the effects of blood-borne angiotensin II (ANG II) including the increase in water drinking and blood pressure and the release of vasopressin from the pituitary. Water 127-132 angiotensinogen Homo sapiens 77-91 2626449-5 1989 This effect was not due to a lesion-induced change in the pharmacokinetics of alcohol and was observed only in those animals whose lesions produced a functional deficit, i.e., abolishing the increase in water drinking produced by ANG II. Water 203-208 angiotensinogen Homo sapiens 230-236 2626449-1 1989 The subfornical organ plays a role in a number of the effects of blood-borne angiotensin II (ANG II) including the increase in water drinking and blood pressure and the release of vasopressin from the pituitary. Water 127-132 angiotensinogen Homo sapiens 93-99 2655608-2 1989 Angiotensin II (AII) acts as a potent pressor agent directly, by virtue of its vasoconstrictor activity and indirectly, by the volume expansion resulting from stimulation of aldosterone release from the adrenal cortex, leading to sodium and water retention. Water 241-246 angiotensinogen Homo sapiens 0-14 2736884-12 1989 ANG II also reduced fractional distal delivery [(sodium clearance plus free water clearance) divided by creatinine clearance], another measure of proximal tubular outflow. Water 76-81 angiotensinogen Homo sapiens 0-6 2727248-1 1989 Angiotensin II (AII; 300 ng) injected into the lateral cerebral ventricle produced significant drinking responses and also stimulated release of lysine vasopressin (LVP) in conscious, water replete, unrestrained minipigs. Water 184-189 angiotensinogen Homo sapiens 0-14 2727248-1 1989 Angiotensin II (AII; 300 ng) injected into the lateral cerebral ventricle produced significant drinking responses and also stimulated release of lysine vasopressin (LVP) in conscious, water replete, unrestrained minipigs. Water 184-189 angiotensinogen Homo sapiens 16-19 2727248-3 1989 At the end of the experiment the level was inversely proportional to the volume of water drunk in response to the AII, and not to changes in plasma osmolality. Water 83-88 angiotensinogen Homo sapiens 114-117 2655608-2 1989 Angiotensin II (AII) acts as a potent pressor agent directly, by virtue of its vasoconstrictor activity and indirectly, by the volume expansion resulting from stimulation of aldosterone release from the adrenal cortex, leading to sodium and water retention. Water 241-246 angiotensinogen Homo sapiens 16-19 2474096-6 1989 Angiotensin II, by its hemodynamic and tubular effects, modulates renal sodium and water excretion and has an important role in blood pressure regulation. Water 83-88 angiotensinogen Homo sapiens 0-14 2965232-3 1987 In this study we investigated a further possible interaction between ANP and angiotensin II (ANG II) in the control of renal water and electrolyte excretion. Water 125-130 angiotensinogen Homo sapiens 77-91 2965633-0 1988 Effects of angiotensin II and atrial natriuretic peptide alone and in combination on urinary water and electrolyte excretion in man. Water 93-98 angiotensinogen Homo sapiens 11-25 2965232-3 1987 In this study we investigated a further possible interaction between ANP and angiotensin II (ANG II) in the control of renal water and electrolyte excretion. Water 125-130 angiotensinogen Homo sapiens 93-99 2965232-7 1987 These results suggest that ANP and ANG II interact within the kidney in the control of water and electrolyte excretion. Water 87-92 angiotensinogen Homo sapiens 35-41 3555207-3 1987 Clinical consequences of these neurohumoral changes are: excessive increase of aortic impedance and myocardial work, salt and water retention a processus which is angiotensin II-dependent, and eventually, hyponatremia. Water 126-131 angiotensinogen Homo sapiens 163-177 3035468-7 1987 Renal effects of angiotensin II and aldosterone are responsible for sodium and water retention. Water 79-84 angiotensinogen Homo sapiens 17-31 3037891-2 1987 Angiotensin II supported systemic BP by direct systemic vasoconstriction, by facilitating the central and peripheral effects of the sympathetic nervous system, by promoting renal sodium retention by the production of aldosterone, and by increasing total body water by enhancing thirst and the synthesis of vasopressin. Water 259-264 angiotensinogen Homo sapiens 0-14 3025536-0 1986 Enhancing effects of angiotensin I on the vasopressin-stimulated water flow of toad bladder through increased cyclic AMP in mucosal cells. Water 65-70 angiotensinogen Homo sapiens 21-34 3025536-2 1986 Angiotensin I at concentrations of 10(-6) and 10(-7) M enhanced the water flow, but angiotensin II failed to do so at these concentrations. Water 68-73 angiotensinogen Homo sapiens 0-13 3025536-6 1986 These results indicate that angiotensin I enhances vasopressin-stimulated water flow by increasing cyclic AMP production in bladder cells and that angiotensin II may possibly interfere with angiotensin I in a competitive manner. Water 74-79 angiotensinogen Homo sapiens 28-41 3769519-1 1986 Because cholecystokinin octapeptide and angiotensin II are directly involved in intestinal food and water absorption, the effect of these two compounds on intestinal motor responses of hibernating and alert 13-lined ground squirrels was investigated. Water 100-105 angiotensinogen Homo sapiens 40-54 3536587-2 1986 Recent studies, however, have demonstrated that in several forms of chronic hypertension caused by aldosterone, angiotensin II (AngII), vasopressin, or norepinephrine and adrenocorticotropin, increased renal arterial pressure is essential for maintaining normal excretion of sodium and water in the face of reduced renal excretory capability. Water 286-291 angiotensinogen Homo sapiens 128-133 3514280-7 1986 Thus, the intrarenal effects of AngII provide a mechanism for stabilizing the GFR and excretion of metabolic waste products while causing sodium and water retention, thereby helping to regulate body fluid volumes and arterial pressure. Water 149-154 angiotensinogen Homo sapiens 32-37 6325596-1 1984 The interaction between human angiotensin-II and Mn(II) ions in water solution has been delineated by nmr and esr experiments. Water 64-69 angiotensinogen Homo sapiens 30-44 2943141-12 1986 Angiotensin II exerts about the same effects as norepinephrine--vasoconstriction, rerouting of blood within the kidney and preferential vasoconstriction of the efferent arterioles--all changes contributing to the retention of salt and water. Water 235-240 angiotensinogen Homo sapiens 0-14 3887946-4 1985 Micropuncture and microperfusion studies have demonstrated that proximal tubular sodium and water transport are stimulated by physiological concentrations (10(-12) to 10(-10) M) of ANG II on the peritubular side, whereas higher doses (10(-7) M) cause inhibition. Water 92-97 angiotensinogen Homo sapiens 181-187 2579567-1 1985 Receptor occupation by a variety of Ca2+-mobilizing hormones, such as alpha 1-adrenergic agents, vasopressin and angiotensin II, causes a rapid phosphodiesterase-mediated hydrolysis of phosphatidylinositol-4,5-bisphosphate in the plasma membrane with the production of the water soluble compound myo-inositol-1,4,5-trisphosphate (IP3) and the lipophilic molecule 1,2-diacylglycerol (DG). Water 273-278 angiotensinogen Homo sapiens 113-127 3519238-5 1986 Water loading-induced suppression of Ang II and AVP was inhibited by captopril therapy. Water 0-5 angiotensinogen Homo sapiens 37-43 3893156-2 1985 At low doses, ANG II stimulates sodium (Na) and water absorption from all intestinal areas. Water 48-53 angiotensinogen Homo sapiens 14-20 3893156-8 1985 ANG II also exerts a dose-dependent dual action on intestinal ion and water absorption in vitro. Water 70-75 angiotensinogen Homo sapiens 0-6 6824944-0 1983 Chronic infusion of angiotensin II into the olfactory bulb elicits an increase in water intake. Water 82-87 angiotensinogen Homo sapiens 20-34 6824944-1 1983 Chronic infusion of angiotensin II (ANG II) into the olfactory bulb (OB) elicited a moderate dipsogenesis which occurred only during the dark phase, essentially doubling the water-to-food intake ratio. Water 174-179 angiotensinogen Homo sapiens 20-34 6824944-1 1983 Chronic infusion of angiotensin II (ANG II) into the olfactory bulb (OB) elicited a moderate dipsogenesis which occurred only during the dark phase, essentially doubling the water-to-food intake ratio. Water 174-179 angiotensinogen Homo sapiens 36-42 6824944-2 1983 Removal of the food from the ANG II-OB group reduced water consumption to the level of the saline-infused/food-deprived controls. Water 53-58 angiotensinogen Homo sapiens 29-35 7248274-2 1981 The peptide amide hydrogen exchange rate of human angiotensin II in H2O have been measured at room temperature by the transfer of solvent saturation method. Water 68-71 angiotensinogen Homo sapiens 50-64 7129754-4 1982 The comparison of computed and experimental properties related to non radiative energy transfer of angiotensin II analogs, assuming that an ensemble of conformers is a satisfactory representation of the state of these molecules in water, provides further support for the model. Water 231-236 angiotensinogen Homo sapiens 99-113 6802291-5 1982 At the higher dose of the diuretic this fall in blood pressure correlated with weight loss, suggesting that when the diuretic-induced compensatory rise in angiotensin II is prevented by captopril the fall in blood pressure becomes dependent on loss of sodium and water. Water 263-268 angiotensinogen Homo sapiens 155-169 6764737-11 1982 Severe volume depletion may induce RAS hyperactivity to such an extent that generated angiotensin II stimulates the ADH release and water intake. Water 132-137 angiotensinogen Homo sapiens 86-100 7428699-0 1980 Stimulation of intestinal sodium and water transport in vivo by angiotensin II and analogs. Water 37-42 angiotensinogen Homo sapiens 64-78 7212095-3 1981 Although there are without question multiple mediators of thirst associated with extracellular thirst challenges, one of the major factors responsible for water intake has been hypothesized to be the action of angiotensin II. Water 155-160 angiotensinogen Homo sapiens 210-224 7212095-1 1981 The systemic administration of angiotensin II or its precursors will result in increased water intake. Water 89-94 angiotensinogen Homo sapiens 31-45 4375541-0 1974 Effect of ablation of the subfornical organ on water intake elicited by systemically administered angiotensin-II. Water 47-52 angiotensinogen Homo sapiens 98-112 19604991-3 1977 Even after a delay of 1.0 h, A-II-injected animals showed increased water consumption compared to controls. Water 68-73 angiotensinogen Homo sapiens 29-33 19604991-4 1977 Animals injected with A-II and tested immediately consumed significantly more water than the 1 h delay animals. Water 78-83 angiotensinogen Homo sapiens 22-26 1255068-0 1976 Proceedings: Evidence that the salt- and water-retaining actions of angiotensin II upon the kidney in vivo are not affected by the protein synthesis inhibitor cycloheximide. Water 41-46 angiotensinogen Homo sapiens 68-82 391545-4 1979 Water intake is increased after venous administration of angiotensin-II within physiological concentrations. Water 0-5 angiotensinogen Homo sapiens 57-71 30650-4 1978 Recently, it has been shown that angiotensin II, infused intravenously or through the carotid artery at rates that produce increases in plasma angiotensin II levels similar to those that occur in mild sodium depletion, causes the water-replete animal to drink. Water 230-235 angiotensinogen Homo sapiens 33-47 30650-4 1978 Recently, it has been shown that angiotensin II, infused intravenously or through the carotid artery at rates that produce increases in plasma angiotensin II levels similar to those that occur in mild sodium depletion, causes the water-replete animal to drink. Water 230-235 angiotensinogen Homo sapiens 143-157 191849-2 1976 If the cannulae in the preoptice region were angled to bypass the lateral ventricles water intake elicited by ANG II was less and pretreating the cerebral ventricles with saralasin acetate did not reduce the drinking response. Water 85-90 angiotensinogen Homo sapiens 110-116 1013169-7 1976 Results demonstrate that angiotensin II decreased lever pressing and increased schedule induced water consumption without a concomitant increase in licking. Water 96-101 angiotensinogen Homo sapiens 25-39 1013169-9 1976 Under these conditions angiotensin II increased water consumption. Water 48-53 angiotensinogen Homo sapiens 23-37 4377498-0 1974 Effect of a competitive antagonist (8-leu-angiotensin II) of angiotensin II on sodium and water transport in toad skin. Water 90-95 angiotensinogen Homo sapiens 42-56 4377498-0 1974 Effect of a competitive antagonist (8-leu-angiotensin II) of angiotensin II on sodium and water transport in toad skin. Water 90-95 angiotensinogen Homo sapiens 61-75 14284891-0 1965 [THE EFFECT OF COMBINED INFUSION OF L-NORADRENALINE AND ANGIOTENSIN II ON THE RENAL WATER-ELECTROLYTE EXCRETION IN NORMAL PERSONS. Water 84-89 angiotensinogen Homo sapiens 56-70 4332863-0 1971 Effects of centrally administered angiotensin II on salt and water excretion. Water 61-66 angiotensinogen Homo sapiens 34-48 30702925-2 2019 Previously, our lab showed in vitro heteromer formation between angiotensin II receptor type 1 subtype a (AT1aR) and secretin receptor (SCTR), which is involved in in vivo control of hyperosmolality-induced water drinking behavior. Water 207-212 angiotensinogen Homo sapiens 64-78 31237219-5 2020 RESULTS: Angiotensin II (ANG II), beside stimulating aldosterone, vasopressin and CRH-ACTH release, sodium and water retention, thirst, and sympathetic nerve activity, exerts its effects on the immune system via the Angiotensin Type 1 Receptor (AT 1R) that is located in the brain, pituitary adrenal gland, and kidney. Water 111-116 angiotensinogen Homo sapiens 9-23 31237219-5 2020 RESULTS: Angiotensin II (ANG II), beside stimulating aldosterone, vasopressin and CRH-ACTH release, sodium and water retention, thirst, and sympathetic nerve activity, exerts its effects on the immune system via the Angiotensin Type 1 Receptor (AT 1R) that is located in the brain, pituitary adrenal gland, and kidney. Water 111-116 angiotensinogen Homo sapiens 25-31 33745438-17 2021 CONCLUSION: Hormonal imbalance between ANG II, VP, and SNS may induce hypertension and impaired water-electrolyte balance in cardiovascular diseases. Water 96-101 angiotensinogen Homo sapiens 39-45 30702925-5 2019 The results from this study not only are consistent with our hypothesis that SCT and ANGII interact at the receptor level to mediate their water homeostatic activities but also provide evidence for in vivo functions of cross-class GPCR heteromers.-Mak, S. O. K., Zhang, L., Chow, B. K. C. In vivo actions of SCTR/AT1aR heteromer in controlling Vp expression and release via cFos/cAMP/CREB pathway in magnocellular neurons of PVN. Water 139-144 angiotensinogen Homo sapiens 85-90 27279485-4 2017 Some of the better-characterized regulators of water and salt homeostasis include angiotensin II, aldosterone, arginine vasopressin, and oxytocin. Water 47-52 angiotensinogen Homo sapiens 82-96 29556787-6 2018 Thirdly, the cooperative action of Ang II acting on AT1R and AVP stimulating both V1aR and V2 receptors in the kidney is necessary for the appropriate regulation of renal blood flow and the efficient resorption of sodium and water. Water 225-230 angiotensinogen Homo sapiens 35-41 29556787-8 2018 In this review, we (1) point attention to the role of the cooperative action of Ang II and AVP for the regulation of blood pressure and the water-electrolyte balance under physiological conditions, (2) present the subcellular mechanisms underlying interactions of these two peptides, and (3) provide evidence that dysregulation of the cooperative action of Ang II and AVP significantly contributes to the development of disturbances in the regulation of blood pressure and the water-electrolyte balance in cardiovascular diseases. Water 140-145 angiotensinogen Homo sapiens 80-86 29556787-8 2018 In this review, we (1) point attention to the role of the cooperative action of Ang II and AVP for the regulation of blood pressure and the water-electrolyte balance under physiological conditions, (2) present the subcellular mechanisms underlying interactions of these two peptides, and (3) provide evidence that dysregulation of the cooperative action of Ang II and AVP significantly contributes to the development of disturbances in the regulation of blood pressure and the water-electrolyte balance in cardiovascular diseases. Water 477-482 angiotensinogen Homo sapiens 80-86