PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33032403-5 2020 The water mobility-represented by alpha as a function of ln tau-differed dramatically between the R (oxygenated) state and the T (deoxygenated) state of Hb at physiologically relevant concentrations (30 g/dl-35 g/dl or 4.5 mM-5.5 mM). Water 4-9 microtubule associated protein tau Homo sapiens 60-63 34454984-7 2021 D(t) and tau of water diffusing along and perpendicular to vessels/tracheids main axes together with relaxation times and an were quantified. Water 16-21 microtubule associated protein tau Homo sapiens 9-12 34361612-3 2021 Analysis of the relaxation times tau and activation energy DeltaE of the dielectric relaxation process revealed the inhibitor was involved in hydrogen bonding and the disruption of the local structures of water molecules. Water 205-210 microtubule associated protein tau Homo sapiens 33-36 34680401-5 2021 In addition, different water- and lipid-soluble vitamins have also prevented amyloid beta and tau pathology. Water 23-28 microtubule associated protein tau Homo sapiens 94-97 34982299-0 2022 Deep Sea Water Alleviates Tau Phosphorylation and Cognitive Impairment via PI3K/Akt/GSK-3beta Pathway. Water 9-14 microtubule associated protein tau Homo sapiens 26-29 33897301-11 2021 Water residence time (tau) and water-level change were associated with HydrAP ranks, demonstrating the framework"s intended ability to differentiate anthropogenic stressors that can alter lake hydrology. Water 0-5 microtubule associated protein tau Homo sapiens 22-25 33983544-4 2021 The taurine-modified graphene oxide carrier (Tau-GO) was synthesized by chemical method to obtain Tau-GO that has a good dispersibility and stability in water, with a zeta potential of - 38.8 mV and a particle size of 242 nm. Water 153-158 microtubule associated protein tau Homo sapiens 45-48 33983544-4 2021 The taurine-modified graphene oxide carrier (Tau-GO) was synthesized by chemical method to obtain Tau-GO that has a good dispersibility and stability in water, with a zeta potential of - 38.8 mV and a particle size of 242 nm. Water 153-158 microtubule associated protein tau Homo sapiens 98-101 33370882-8 2020 Under climate change, water scarcity in these sub-catchments will exhibit high dependency (Kendall tau correlation coefficient = 0.84) on water-use patterns than on water availability. Water 22-27 microtubule associated protein tau Homo sapiens 99-102 33370882-8 2020 Under climate change, water scarcity in these sub-catchments will exhibit high dependency (Kendall tau correlation coefficient = 0.84) on water-use patterns than on water availability. Water 138-143 microtubule associated protein tau Homo sapiens 99-102 33370882-8 2020 Under climate change, water scarcity in these sub-catchments will exhibit high dependency (Kendall tau correlation coefficient = 0.84) on water-use patterns than on water availability. Water 138-143 microtubule associated protein tau Homo sapiens 99-102 31358628-9 2019 A variety of experiments and polarization transfer from water and mobile side chains indicate that 0N4R tau fibrils exhibit heterogeneous dynamics: Outside the rigid R2-R3 core, the R1 and R4 repeats are semirigid even though they exhibit beta-strand character and the proline-rich domains undergo large-amplitude anisotropic motions, whereas the two termini are nearly isotropically flexible. Water 56-61 microtubule associated protein tau Homo sapiens 104-107 33275022-2 2020 We build an experimental apparatus to test the predicted long-time 1/tau scaling of the irreversible entropy generation in the finite-time (tau) thermodynamic process by compressing dry air in a temperature-controlled water bath. Water 218-223 microtubule associated protein tau Homo sapiens 69-72 33275022-2 2020 We build an experimental apparatus to test the predicted long-time 1/tau scaling of the irreversible entropy generation in the finite-time (tau) thermodynamic process by compressing dry air in a temperature-controlled water bath. Water 218-223 microtubule associated protein tau Homo sapiens 140-143 32770092-4 2020 Despite being charged and soluble, the tau proteins were also highly surface active and favorably interacted with anionic lipid monolayers at the air/water interface. Water 150-155 microtubule associated protein tau Homo sapiens 39-42 32770092-5 2020 Membrane binding of tau also led to the formation of a macroscopic, gelatinous layer at the air/water interface, possibly related to tau phase separation. Water 96-101 microtubule associated protein tau Homo sapiens 20-23 32770092-5 2020 Membrane binding of tau also led to the formation of a macroscopic, gelatinous layer at the air/water interface, possibly related to tau phase separation. Water 96-101 microtubule associated protein tau Homo sapiens 133-136 30747516-6 2019 In more detail, this agent interrupts the network between water molecules and weakens the hydrophobic interactions between proteins, remarkably improving detection capabilities to target tau protein. Water 58-63 microtubule associated protein tau Homo sapiens 187-190 28859549-11 2018 A battery of behavioral tests revealed that TBI in hTau mice resulted in compromised use of spatial search strategies to complete a water maze task, despite lack of motor or visual deficits. Water 132-137 microtubule associated protein tau Homo sapiens 51-55 26687814-8 2016 In contrast, perinatal tau and tau in cold water-stressed mice were all phosphorylated with a similar extent of phosphorylation. Water 43-48 microtubule associated protein tau Homo sapiens 23-26 26687814-8 2016 In contrast, perinatal tau and tau in cold water-stressed mice were all phosphorylated with a similar extent of phosphorylation. Water 43-48 microtubule associated protein tau Homo sapiens 31-34 25918405-0 2015 Hydration water mobility is enhanced around tau amyloid fibers. Water 10-15 microtubule associated protein tau Homo sapiens 44-47 25918405-5 2015 In comparison with monomeric tau, hydration water on the surface of tau fibers is more mobile, as evidenced by an increased fraction of translationally diffusing water molecules, a higher diffusion coefficient, and increased mean-squared displacements in neutron scattering experiments. Water 44-49 microtubule associated protein tau Homo sapiens 68-71 25918405-5 2015 In comparison with monomeric tau, hydration water on the surface of tau fibers is more mobile, as evidenced by an increased fraction of translationally diffusing water molecules, a higher diffusion coefficient, and increased mean-squared displacements in neutron scattering experiments. Water 162-167 microtubule associated protein tau Homo sapiens 68-71 25918405-6 2015 Fibers formed by the hexapeptide (306)VQIVYK(311) were taken as a model for the tau fiber core and studied by molecular dynamics simulations, revealing that hydration water dynamics around the core domain is significantly reduced after fiber formation. Water 167-172 microtubule associated protein tau Homo sapiens 80-83 25918405-7 2015 Thus, an increase in water dynamics around the fuzzy coat is proposed to be at the origin of the experimentally observed increase in hydration water dynamics around the entire tau fiber. Water 21-26 microtubule associated protein tau Homo sapiens 176-179 25918405-7 2015 Thus, an increase in water dynamics around the fuzzy coat is proposed to be at the origin of the experimentally observed increase in hydration water dynamics around the entire tau fiber. Water 143-148 microtubule associated protein tau Homo sapiens 176-179 25918405-9 2015 Detection of the enhanced hydration water mobility around tau fibers is conjectured to potentially contribute to the early diagnosis of Alzheimer patients by diffusion MRI. Water 36-41 microtubule associated protein tau Homo sapiens 58-61 19096159-4 2008 Cognitive function was also normal in the tau mice evaluated in the radial arm water maze and the Y-maze tasks. Water 79-84 microtubule associated protein tau Homo sapiens 42-45 30367970-5 2019 Furthermore, using a radial arm water maze, the main effect was observed on working memory which was significantly impaired in Abeta-Tau group only 3 months post injections. Water 32-37 microtubule associated protein tau Homo sapiens 133-136 27842175-12 2017 Furthermore, significant age-by-biomarker interactions were observed between myelin water fraction and phosphorylated tau 181/beta-amyloid 42, suggesting that phosphorylated tau 181/beta-amyloid 42 levels modulate age-related changes in myelin water fraction. Water 84-89 microtubule associated protein tau Homo sapiens 174-177 27842175-12 2017 Furthermore, significant age-by-biomarker interactions were observed between myelin water fraction and phosphorylated tau 181/beta-amyloid 42, suggesting that phosphorylated tau 181/beta-amyloid 42 levels modulate age-related changes in myelin water fraction. Water 244-249 microtubule associated protein tau Homo sapiens 118-121 27842175-12 2017 Furthermore, significant age-by-biomarker interactions were observed between myelin water fraction and phosphorylated tau 181/beta-amyloid 42, suggesting that phosphorylated tau 181/beta-amyloid 42 levels modulate age-related changes in myelin water fraction. Water 244-249 microtubule associated protein tau Homo sapiens 174-177 22860163-1 2011 The synthesis of a water/plasma soluble, noncytotoxic, "clicked" sugar-derivative of curcumin with amplified bioefficacy in modulating amyloid-beta and tau peptide aggregation is presented. Water 19-24 microtubule associated protein tau Homo sapiens 152-155 16225961-0 2006 Copper binding properties of a tau peptide associated with Alzheimer"s disease studied by CD, NMR, and MALDI-TOF MS. We have previously reported the copper binding properties of R3 peptide (residues 318-335: VTSKCGSLGNIHHKPGGG, according to the longest tau protein) derived from the third repeat microtubule-binding domain of water-soluble tau protein. Water 326-331 microtubule associated protein tau Homo sapiens 31-34 14660656-4 2004 Anomalous UVRR enhancement of amide bands at 229 nm results from gel structure, as demonstrated by increased amide absorption at the red edge for tau 2-19 gel and implies the involvement of water in gel structure. Water 190-195 microtubule associated protein tau Homo sapiens 146-149 14660656-5 2004 In aged, dehydrated tau 2-19 gel, proline carbonyls lose their bonds to water and tyrosine becomes deprotonated, as demonstrated by UVRR spectroscopy. Water 72-77 microtubule associated protein tau Homo sapiens 20-23 14660656-8 2004 One implication of this assignment is that the fibrillation of hydrophilic tau is thermodynamically driven by the entropy gained as hydrogen-bonded water is freed, as for collagen I. Water 148-153 microtubule associated protein tau Homo sapiens 75-78 12427043-8 2002 Only noncooperative thermal transitions were observed for the PHF samples in acetate buffer and water, consistent with the presence of a heterogeneous population of folded structures. Water 96-101 microtubule associated protein tau Homo sapiens 62-65