PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6276836-2 1981 Calculations for various possible mixtures of CH4, CO2, CO, N2, H2, and H2O reveal that the prime species produced were probably HCN and NO and that the key parameter determining the rates of fixation was the ratio of C atoms to O atoms in the atmosphere. Water 72-75 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 129-132 1208098-2 1975 In the presence of water vapor, aldehydes and HCN are formed separately in regions of different temperatures along the reacting gas. Water 19-24 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 46-49 31820987-0 2020 Formation of Formamide from HCN + H2O: A Computational Study on the Roles of 2ND H2O as a Catalyst, as a Spectator and as a Reactant. Water 81-84 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 28-31 33579010-5 2021 An example is given of photochemical dissipative abiogenesis of adenine from the precursor HCN in water solvent within a fatty acid vesicle floating on a hot ocean surface and driven far from equilibrium by the incident UVC light. Water 98-103 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 91-94 32453572-9 2020 Complexation with HCN remains endothermic in water, although less so and the exothermicity of pnicogen bond formation with pyridine is enhanced by solvation. Water 45-50 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 18-21 31820987-2 2020 In this work, using quantum mechanical computations, reactions between HCN and H2O, leading to the formation of formamide, have been analysed. Water 79-82 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 71-74 30063827-2 2018 However, besides glycine, a plethora of other compounds are also generated when CH2O and HCN react in the presence of ammonia and water. Water 130-135 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 89-92 31266303-5 2019 Control and mechanistic investigations reveal that HCN formed during laser irradiation reacts rapidly to reduce the Cu(II) centers in [Cu(OAc)2]2, leading to the formation of CuCN or, in the presence of water, Cu2O nanoparticles that bind and cross-link CuCN-polyacetonitrile chains. Water 203-208 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 51-54 30185991-7 2018 In the hot inner regions, H2O, and simple organic molecules like C2H2, HCN, and CH4 are predicted to be very abundant in T Tauri disks and even more in Herbig Ae/Be disks, in contrast with infrared observations that find a much lower detection rate of water and simple organics toward disks around hotter stars. Water 252-257 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 71-74 27016454-1 2016 What chemical species might be found if water or ammonia reacts with HCN in aqueous solution under neutral conditions? Water 40-45 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 69-72 29442311-3 2018 Adding H2O decreased the possibility of reactions between the reductive groups (NH) and the oxygen radical during devolatilization, which led to a decrease in NO emissions at 1000 C. However, as the furnace temperature increased, "additional" nitrogen precursors (HCN and NH3) generated by enhanced char-H2O gasification were quickly oxidized to generate a large amount of NO during char oxidation that exceeded the amount of NO reduced by NH during devolatilization. Water 7-10 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 265-268 29561787-5 2018 In this study, the effects of H2O on pyrrole pyrolysis to form NOx precursors HCN and NH3 are investigated using the density functional theory (DFT) method. Water 30-33 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 78-81 29561787-6 2018 The calculation results indicate that the presence of H2O can lead to the formation of both NH3 and HCN during pyrrole pyrolysis, while only HCN is formed in the absence of H2O. Water 54-57 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 100-103 28718926-0 2017 ETS-NOCV Decomposition of the Reaction Force: The HCN/CNH Isomerization Reaction Assisted by Water. Water 93-98 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 50-53 28718926-2 2017 This approach, together with the analysis of reaction electronic flux (REF), has been applied in a description of the changes in the electronic structure along the IRC pathway for the HCN/CNH isomerization reaction assisted by water. Water 227-232 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 184-187 29561787-9 2018 On the contrary, HCN will be generated instead of NH3 when H2O attacks the C3 position of pyrrole with its hydroxyl group. Water 59-62 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 17-20 28218316-0 2017 Theoretical study of HCN-water interaction: five dimensional potential energy surfaces. Water 25-30 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 21-24 28218316-1 2017 A new five-dimensional potential energy surface is calculated at the coupled-cluster CCSD(T) level of theory for the HCN-water system, treating both monomers as rigid rotors. Water 121-126 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 117-120 27687077-5 2016 When the substances with the cited hazard statement codes react with water or an acid, they can release HCl, Cl2, HF, HCN, PH3, H2S, SO2 (and two other gases very unlikely to be emitted, hydrazoic acid HN3 and selenium oxide SeO2 - a solid with low vapor pressure). Water 69-74 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 118-121 26204389-2 2015 Undissociated volatile acid eluites (e.g., H2S, HCN, H2CO3, etc., represented as HA) transfer through the membrane and react as OH(-) + HA A(-) + H2O; the conversion of high-mobility OH(-) to lower mobility A(-) results in a significant negative response for these analytes. Water 148-151 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 48-51 27178416-4 2016 Interaction energy values of -19.90, -19.66, -14.01, -8.70, and -4.76 kJ mol(-1) were achieved for adsorption of SO3, H2O, NH3, HCN, and H2S on 3PT, respectively. Water 118-121 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 128-131 24832217-1 2014 The efficient formation of HCN/HNC from formamide (FM) combining the advantages of water-assistance, self-catalyzed reactions, and the mineral surfaces was investigated. Water 83-88 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 27-30 25486065-1 2015 A novel derivatization method of free cyanide (HCN + CN(-)) including cyanogen chloride in chlorinated drinking water was developed with d-cysteine and hypochlorite. Water 112-117 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 47-50 23461351-8 2013 With the presence of one water molecule, the dehydration pathway leading to HCN is favored. Water 25-30 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 76-79 23889466-7 2013 Dehydration pathways from the neutral S1 and protonated T1 forms lead to stable complexes of HCN and HNC with water but are associated with large energy barriers. Water 110-115 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 93-96 23536286-6 2013 In conclusion, an acetylene-containing atmosphere could contribute to the origin of nucleobases in the presence of a urea/water system by an HCN-independent mechanism. Water 122-127 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 141-144 22892540-4 2012 The former undergoes a charge separation reaction yielding [Ca(NH(2))](+) + HCO(+), and the latter undergoes the most favorable Coulomb explosion yielding [Ca-OH](+) + [HCNH](+) and is the origin of a multistep mechanism which accounts for the observed loss of water and HCN. Water 261-266 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 169-172 18336024-9 2008 In the presence of trace water, CN- hydrolysis yields HCN that reacts with Pd(0) to give [(CN)3PdH]2-. Water 25-30 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 54-57 22253100-3 2012 We suggest that "insoluble black HCN polymers" are formed by an unsaturated complex matrix, which retains a significant amount of H(2) O and important bioorganic compounds or their precursors. Water 130-136 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 33-36 19117474-6 2009 Insertion of small doses of HCN or ammonia does not change the acid/base strength of dangling hydroxyl groups or coordinately unsaturated surface oxygen atoms, but it changes the proportion between the concentrations of these sites as compared with pure water ice. Water 254-259 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 28-31 19810406-7 2006 Irrespective of the method used, the hydrogen bond donor radius increases in the order HF < HCl < H2O < HBr < HCN < HCCH < H2S, but mostly lie between Pauling"s covalent and van der Waals radii of H atom. Water 104-107 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 122-125 16928122-1 2006 An ab initio study of the stability, spectroscopic properties, and isomeric equilibrium of the hydrogen-bonded HCN...H2O and H2O...HCN isomers is presented. Water 117-120 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 111-114 16928122-1 2006 An ab initio study of the stability, spectroscopic properties, and isomeric equilibrium of the hydrogen-bonded HCN...H2O and H2O...HCN isomers is presented. Water 125-128 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 131-134 16928122-0 2006 Ab initio study of the isomeric equilibrium of the HCN...H2O and H2O...HCN hydrogen-bonded clusters. Water 57-60 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 51-54 16928122-3 2006 At the best theoretical level, CCSD(T), the H2O...HCN complex is more stable than the HCN...H2O complex by ca. Water 44-47 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 50-53 16928122-0 2006 Ab initio study of the isomeric equilibrium of the HCN...H2O and H2O...HCN hydrogen-bonded clusters. Water 65-68 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 71-74 16928122-3 2006 At the best theoretical level, CCSD(T), the H2O...HCN complex is more stable than the HCN...H2O complex by ca. Water 44-47 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 86-89 16928122-3 2006 At the best theoretical level, CCSD(T), the H2O...HCN complex is more stable than the HCN...H2O complex by ca. Water 92-95 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 50-53 16928122-3 2006 At the best theoretical level, CCSD(T), the H2O...HCN complex is more stable than the HCN...H2O complex by ca. Water 92-95 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 86-89 16928122-8 2006 We find that under typical conditions of supersonic expansion experiments (T < 150 K) H2O...HCN is essentially the only isomer present. Water 89-92 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 95-98 12214855-2 2002 Amygdalin in water is decomposed into benzaldehyde, HCN, and glucose by emulsin, a hydrolysis enzyme in tonin. Water 13-18 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 52-55 15329882-2 2004 Because of the proximity of the proton affinities of HCN and H2O molecules, the presence of water vapour can significantly distort HCN analysis in the presence of water vapour and a more sophisticated analytical procedure has to be developed. Water 61-64 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 131-134 15329882-2 2004 Because of the proximity of the proton affinities of HCN and H2O molecules, the presence of water vapour can significantly distort HCN analysis in the presence of water vapour and a more sophisticated analytical procedure has to be developed. Water 92-97 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 53-56 15329882-2 2004 Because of the proximity of the proton affinities of HCN and H2O molecules, the presence of water vapour can significantly distort HCN analysis in the presence of water vapour and a more sophisticated analytical procedure has to be developed. Water 92-97 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 131-134 15329882-2 2004 Because of the proximity of the proton affinities of HCN and H2O molecules, the presence of water vapour can significantly distort HCN analysis in the presence of water vapour and a more sophisticated analytical procedure has to be developed. Water 163-168 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 53-56 15329882-2 2004 Because of the proximity of the proton affinities of HCN and H2O molecules, the presence of water vapour can significantly distort HCN analysis in the presence of water vapour and a more sophisticated analytical procedure has to be developed. Water 163-168 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 131-134 15329882-3 2004 Thus, the reactions of H3O+(H2O)0,1,2,3 ions with HCN molecules have been studied in the presence of varying concentrations of water vapour, reactions on which SIFT-MS analysis of HCN relies. Water 28-31 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 50-53 15329882-3 2004 Thus, the reactions of H3O+(H2O)0,1,2,3 ions with HCN molecules have been studied in the presence of varying concentrations of water vapour, reactions on which SIFT-MS analysis of HCN relies. Water 28-31 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 180-183 16379428-3 2005 RESULTS: The optimum technology of extraction HCN from Semen Armeniacae Amarum was as follows: crushing to pieces, adding 3 times amount of 37 degrees C water and soaking overnight, extracting and collecting 1.33 times amount of extract; the optimum extraction process wasas follows: extracting 2 times, each time adding 12 times amount of water and extracting 1 h. CONCLUSION: The preparation technological process can be used for mass production. Water 153-158 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 46-49 16379428-3 2005 RESULTS: The optimum technology of extraction HCN from Semen Armeniacae Amarum was as follows: crushing to pieces, adding 3 times amount of 37 degrees C water and soaking overnight, extracting and collecting 1.33 times amount of extract; the optimum extraction process wasas follows: extracting 2 times, each time adding 12 times amount of water and extracting 1 h. CONCLUSION: The preparation technological process can be used for mass production. Water 340-345 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 46-49 15792470-0 2005 Solubility, complex formation, and redox reactions in the Tl2O3-HCN/CN(-)-H2O system. Water 74-77 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 64-67 15792470-10 2005 Along with the acidic leaching (enhanced by Tl(III)-CN- complex formation), an effective reductive dissolution of the thallium(III) oxide can also take place in the Tl2O3-HCN-H2O system yielding thallium(I), while hydrogen cyanide is oxidized to cyanogen. Water 175-178 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 171-174 11925162-14 2002 The nucleophilic attack by HCN or solvation by H(2)O is at least nine or six orders of magnitude slower, respectively than is nucleophilic attack by CN(-) for Pt(II), Pd(II), and Ni(II), respectively. Water 47-52 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 27-30 35446575-2 2022 After benchmarking density functional predictions of both geometries and reaction energies against jun-Cheap results for the relatively small model system HCN (H2O)2, the best performing DFT methods are selected. Water 162-165 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 155-158 23686875-1 2001 The potential activation by electron capture of H2+CO2 or CO+H2O reactions, leading to HCOOH (formic acid), and of CO+NH3, HCN+H2O and HNC+H2O reactions, leading to HC(O)NH2 (formamide), have been studied theoretically. Water 61-64 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 123-126 23686875-1 2001 The potential activation by electron capture of H2+CO2 or CO+H2O reactions, leading to HCOOH (formic acid), and of CO+NH3, HCN+H2O and HNC+H2O reactions, leading to HC(O)NH2 (formamide), have been studied theoretically. Water 127-130 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 123-126 23686875-1 2001 The potential activation by electron capture of H2+CO2 or CO+H2O reactions, leading to HCOOH (formic acid), and of CO+NH3, HCN+H2O and HNC+H2O reactions, leading to HC(O)NH2 (formamide), have been studied theoretically. Water 127-130 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 123-126 8188662-8 1994 His64, Gln64, and distal pocket water molecules appear to facilitate deprotonation of HCN, which is the major kinetic barrier to cyanide binding at neutral pH. Water 32-37 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 86-89 1444430-1 1992 Products observed during anaerobic cyanide transformation are consistent with a hydrolytic pathway (HCN + H2O <--> HCONH2 + H2O <--> HCOOH + NH3). Water 106-109 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 100-103 1444430-1 1992 Products observed during anaerobic cyanide transformation are consistent with a hydrolytic pathway (HCN + H2O <--> HCONH2 + H2O <--> HCOOH + NH3). Water 130-133 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 100-103 34954487-3 2022 The mechanism of the solution degradation chemistry was verified by stressing linagliptin API with trimethylsilyl cyanide (TMSCN, which can give off HCN slowly in the presence of water) treated with sonication in the sample preparation. Water 179-184 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 149-152 35537261-1 2022 In this work we present a time-resolved FTIR spectroscopic study on kinetics of atomic and molecular species, specifically CO, CN radical, N2, HCN and CO2 generated in a glow discharge of formamide-nitrogen-water mixture in a helium buffer gas. Water 207-212 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 143-146 35319060-3 2022 1 combined with 1,8-bis(dimethylamino)naphthalene (3, proton sponge) is a Frustrated Lewis pair (FLP) that forms adducts (1-EHn-1)(3-H) with the protic compounds EHn = H2O, NH3, H2S, PH3, H2Se, HCN. Water 168-171 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 194-197 35113000-10 2022 Downregulation of MALAT1 inhibited the neurological scores, brain water content, and neuronal apoptosis, reduced the levels of pro-inflammatory cytokines, and prevented oxidative stress in ICH rats. Water 66-71 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 18-24 6298684-2 1982 Subsequent reactions of HCN with the activated nitrile groups of this HCN homopolymer would then yield heteropolyamidines, readily converted to heteropolypeptides following contact with frozen water on the surface of Titan. Water 193-198 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 24-27 6298684-2 1982 Subsequent reactions of HCN with the activated nitrile groups of this HCN homopolymer would then yield heteropolyamidines, readily converted to heteropolypeptides following contact with frozen water on the surface of Titan. Water 193-198 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 70-73 6298684-4 1982 Any detection of such HCN chemistry by the Voyager missions or the pending Galileo probe would constitute evidence for the hypothesis that heteropolypeptides on the primitive Earth were synthesized directly from hydrogen cyanide and water without the intervening formation of alpha-amino acids. Water 233-238 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 22-25 6087242-2 1984 Energy yields for the synthesis of HCN and H2CO from a spark discharge were determined for various mixtures of CH4, CO, CO2, H2, H2O, N2 and NH3. Water 129-132 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 35-38