PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12443879-0	2002	Arginine butyrate increases the cytotoxicity of DAB(389)IL-2 in leukemia and lymphoma cells by upregulation of IL-2Rbeta gene.	diazobenzenesulfonic acid	48-51	interleukin 2 receptor subunit beta	Homo sapiens	111-120	
12443879-2	2002	In vitro data demonstrates that DAB(389)IL-2 is cytotoxic to cells expressing the high affinity IL-2 receptor (IL-2R).	diazobenzenesulfonic acid	32-35	interleukin 2 receptor subunit beta	Homo sapiens	96-109	
12443879-2	2002	In vitro data demonstrates that DAB(389)IL-2 is cytotoxic to cells expressing the high affinity IL-2 receptor (IL-2R).	diazobenzenesulfonic acid	32-35	interleukin 2 receptor subunit beta	Homo sapiens	111-116	
12443879-7	2002	Our results suggest that the effects of physiologically achievable concentrations of butyrate on IL-2R expression could be exploited to enhance the susceptibility of intermediate and low-affinity IL-2R expressing leukemia cells to DAB(389)IL-2.	diazobenzenesulfonic acid	231-234	interleukin 2 receptor subunit beta	Homo sapiens	97-102	
12443879-7	2002	Our results suggest that the effects of physiologically achievable concentrations of butyrate on IL-2R expression could be exploited to enhance the susceptibility of intermediate and low-affinity IL-2R expressing leukemia cells to DAB(389)IL-2.	diazobenzenesulfonic acid	231-234	interleukin 2 receptor subunit beta	Homo sapiens	196-201	
11707860-5	2000	DAB(486)IL-2, in which the native receptor-binding domain of diphtheria toxin was replaced with the full-length interleukin-2 (IL-2) gene, was capable of intoxicating high-affinity IL-2 receptor-bearing cells in vitro with an IC(50) of 10(-10) M; whereas, cells lacking the full component of the high-affinity IL-2 receptor (p55, p75, p64) were relatively resistant (IC(50) of 10(-8) M).	diazobenzenesulfonic acid	0-3	interleukin 2 receptor subunit beta	Homo sapiens	181-194	
11707860-5	2000	DAB(486)IL-2, in which the native receptor-binding domain of diphtheria toxin was replaced with the full-length interleukin-2 (IL-2) gene, was capable of intoxicating high-affinity IL-2 receptor-bearing cells in vitro with an IC(50) of 10(-10) M; whereas, cells lacking the full component of the high-affinity IL-2 receptor (p55, p75, p64) were relatively resistant (IC(50) of 10(-8) M).	diazobenzenesulfonic acid	0-3	interleukin 2 receptor subunit beta	Homo sapiens	330-333	
16586495-1	2006	BACKGROUND: The safety and efficacy of the interleukin-2 diphtheria toxin fusion protein (DAB(389)IL2; denileukin diftitox) directed against the IL-2 receptor (IL-2R) was tested in patients with recurrent or refractory chronic lymphocytic leukemia (CLL).	diazobenzenesulfonic acid	90-93	interleukin 2 receptor subunit beta	Homo sapiens	145-158